Details of Drug

Drug General Information (ID: D1317)
Drug Name	Potassium bicarbonate
Drug Type	Small molecule
Drug Synonymous	Potassium bicarbonate; 298-14-6; Potassium hydrogen carbonate; Potassium hydrogencarbonate; Potassium acid carbonate; CARBONIC ACID, MONOPOTASSIUM SALT; Monopotassium carbonate; POTASSIUMBICARBONATE; potassium;hydrogen carbonate; KHCO3; UNII-HM5Z15LEBN; HM5Z15LEBN; Potassium bicarbonate [USP]; CHEBI:81862; MFCD00011402; Carbonic acid, potassium salt (1:1); Potassium bicarbonate (USP); CCRIS 3510; EINECS 206-059-0; EPA Pesticide Chemical Code 073508; Armicarb; Kafylox; Kaligreen; Milstop; Purple k; potasium bicarbonate; potassium bicabonate; potassium bicarbonat; PBC; EINECS 241-378-9; K-vescent (TN); potassiumhydrogencarbonate; potassium hydogencarbonate; potassium;hydron;carbonate; CHO3.K; EC 206-059-0; potassium carbonate solution; potassium hydrogen-carbonate; SCHEMBL2420; CHEMBL2106975; DTXSID0021177; INS-501(II); Potassium bicarbonate, ACS grade; 8301AF; E-501(II); AKOS009159056; DB11098; E501; FT-0645098; C18606; D02077; Potassium bicarbonate, Trace metals grade 99.98%; Q410529; J-017655 Click to Show/Hide
Therapeutic Class	Minerals And Electrolytes
Structure
Structure	3D Structure		2D Structure
Formula	CHKO3
InChI	InChI=1S/CH2O3.K/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1
InChIKey	TYJJADVDDVDEDZ-UHFFFAOYSA-M
Canonical SMILES	C(=O)(O)[O-].[K+]
External Link
External Link	Pubchem ID	516893

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects BM058 Increased risk of hyperkalemia BM064 Increased risk of hypoglycemia
Relation Graph

Full list of drugs interacting with Potassium bicarbonate
Pharmacodynamic additive effects
	Increased risk of hyperkalemia					Drug Num: 45
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0058		Amiloride	C6H8ClN7O	16231	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22]
D0138		Azilsartan medoxomil	C30H24N4O8	135409642	Major		Inter Info	[17], [23], [2], [15], [24], [25], [21], [19], [10], [9], [26]
D0156		Benazepril	C24H28N2O5	5362124	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D0254		Captopril	C9H15NO3S	44093	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D0567		Enalapril	C20H28N2O5	5388962	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D0585		Eplerenone	C24H30O6	443872	Major		Inter Info	[3], [40]
D0587		Eprosartan	C23H24N2O4S	5281037	Major		Inter Info	[17], [23], [2], [15], [24], [25], [21], [19], [10], [9], [26]
D0695		Fosinopril	C30H46NO7P	55891	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D0844		Irbesartan	C25H28N6O	3749	Major		Inter Info	[17], [23], [2], [15], [24], [25], [21], [19], [10], [9], [26]
D0938		Lisinopril	C21H31N3O5	5362119	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D0954		Losartan	C22H23ClN6O	3961	Major		Inter Info	[17], [23], [2], [15], [24], [25], [21], [19], [10], [9], [26]
D1082		Moexipril	C27H34N2O7	91270	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D1170		Olmesartan	C24H26N6O3	158781	Major		Inter Info	[17], [23], [2], [15], [24], [25], [21], [19], [10], [9], [26]
D1256		Perindopril	C19H32N2O5	107807	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D1369		Quinapril	C25H30N2O5	54892	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D1379		Ramipril	C23H32N2O5	5362129	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D1501		Spironolactone	C24H32O4S	5833	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22]
D1545		Telmisartan	C33H30N4O2	65999	Major		Inter Info	[17], [23], [2], [15], [24], [25], [21], [19], [10], [9], [26]
D1618		Trandolapril	C24H34N2O5	5484727	Major		Inter Info	[13], [27], [25], [21], [28], [29], [9], [30], [19], [10], [31], [16], [32], [17], [33], [15], [34], [2], [35], [26], [36], [37], [38], [39]
D1631		Triamterene	C12H11N7	5546	Major		Inter Info	[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22]
D1645		Trimethoprim	C14H18N4O3	5578	Major		Inter Info	[41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [9], [10], [55], [56], [57], [58], [59], [60], [61], [21], [22], [62], [19], [3], [63], [64], [65], [66], [67], [68], [69]
D1679		Valsartan	C24H29N5O3	60846	Major		Inter Info	[17], [23], [2], [15], [24], [25], [21], [19], [10], [9], [26]
D0038		Aliskiren	C30H53N3O6	5493444	Moderate		Inter Info	[70]
D0210		Bromfenac	C15H12BrNO3	60726	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0489		Diflunisal	C13H8F2O3	3059	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0536		Drospirenone	C24H30O3	68873	Moderate		Inter Info	[77], [16]
D0624		Etodolac	C17H21NO3	3308	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0645		Fenoprofen	C15H14O3	3342	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0680		Flurbiprofen	C15H13FO2	3394	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0786		Ibuprofen	C13H18O2	3672	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0800		Indomethacin	C19H16ClNO4	3715	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0881		Ketoprofen	C16H14O3	3825	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0882		Ketorolac	C15H13NO3	3826	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0988		Meclofenamic acid	C14H11Cl2NO2	4037	Moderate		Inter Info	[73], [71], [72]
D0991		Mefenamic acid	C15H15NO2	4044	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D1196		Oxaprozin	C18H15NO3	4614	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D1274		Phenylbutazone	C19H20N2O2	4781	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D1300		Piroxicam	C15H13N3O4S	54676228	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D1606		Tolmetin	C15H15NO3	5509	Moderate		Inter Info	[71], [72], [73], [74], [75], [76]
D1608		Tolvaptan	C26H25ClN2O3	216237	Moderate		Inter Info	[78]
	Increased risk of hypoglycemia					Drug Num: 14
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0807		Insulin aspart (aspart protamine)	C256H381N65O79S6	118984445	Minor		Inter Info	[79], [80], [81]
D0808		Insulin aspart (aspart)	C256H381N65O79S6	118984445	Minor		Inter Info	[79], [80], [81]
D0809		Insulin degludec	C274H411N65O81S6	118984462	Minor		Inter Info	[79], [80], [81]
D0810		Insulin detemir	C267H402N64O76S6	16137271	Minor		Inter Info	[79], [80], [81]
D0811		Insulin glargine	C267H404N72O78S6	118984454	Minor		Inter Info	[79], [80], [81]
D0812		Insulin glulisine	C258H384N64O78S6	16136701	Minor		Inter Info	[79], [80], [81]
D0813		Insulin human	C257H383N65O77S6	118984375	Minor		Inter Info	[79], [80], [81]
D0814		Insulin human (inhalation, rapid acting)	C257H383N65O77S6	118984375	Minor		Inter Info	[79], [80], [81]
D0815		Insulin human (isophane)	C257H383N65O77S6	118984375	Minor		Inter Info	[79], [80], [81]
D0816		Insulin human (regular)	C257H383N65O77S6	118984375	Minor		Inter Info	[79], [80], [81]
D0817		Insulin human (zinc extended)	C257H383N65O77S6	118984375	Minor		Inter Info	[79], [80], [81]
D0818		Insulin human (zinc)	C257H383N65O77S6	118984375	Minor		Inter Info	[79], [80], [81]
D0819		Insulin lispro	C257H389N65O77S6	16132438	Minor		Inter Info	[79], [80], [81]
D0820		Insulin lispro (protamine)	C257H389N65O77S6	16132438	Minor		Inter Info	[79], [80], [81]

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40	Product Information. Inspra (eplerenone). Searle, Chicago, IL.
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59	Product Information. Bactrim (trimethoprim-sulfamethoxazole). Roche Laboratories, Nutley, NJ.
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70	Product Information. Tekturna (aliskiren). Novartis Pharmaceuticals, East Hanover, NJ.
71	Product Information. Potassium Chloride ER (potassium chloride). Zydus Pharmaceuticals (USA) Inc, Princeton, NJ.
72	Cerner Multum, Inc. "Australian Product Information.".
73	Product Information. K-Phos Original (potassium acid phosphate). Beach Pharmaceuticals, Tampa, FL.
74	Product Information. Potassium Chloride (potassium chloride). Pharmaceutical Assoc Inc Div Beach Products, Greenville, SC.
75	Product Information. Phospho-Trin 250 Neutral (potassium phosphate-sodium phosphate). Patrin Pharma, Skokie, IL.
76	Product Information. SSKI (potassium iodide). Upsher-Smith Laboratories Inc, Minneapolis, MN.
77	Product Information. Yasmin (drospirenone-ethinyl estradiol) Berlex Laboratories, Richmond, CA.
78	Product Information. Samsca (tolvaptan). Otsuka American Pharmaceuticals Inc, Rockville, MD.
79	DeFronzo RA, Cooke CR, Andres R, Faloona GR, Davis PJ "The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man." J Clin Invest 55 (1975): 845-55
80	Hiatt N, Davidson MB, Bonorris G "The effect of potassium chloride infusion on insulin secretion in vivo." Horm Metab Res 4 (1972): 64-8
81	Conn HO "Cirrhosis and diabetes. IV. Effect of potassium chloride administration on glucose and insulin metabolism." Am J Med Sci 259 (1970): 394-404

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