Drug General Information (ID: D1303)
  Drug Name
Plantago seed
  Drug Type Natural product
  Drug Synonymous
DB11097; Plantago seed; Psyllium; Psyllium husk
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  Therapeutic Class Herbal Products

Drug-Drug Interaction Network
  Sunburst Graph
AM003  Affected organization distribution
AM006  Pharmacodynamic additive effects
BM014  Interference of cell/tissue uptake
BM064  Increased risk of hypoglycemia
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Plantago seed
      Affected organization distribution
   Interference of cell/tissue uptake Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0670
 
Fludeoxyglucose (18F)
 
C6H11FO5
 
170049 
Moderate    Inter Info   
[1], [2], [3]
      Pharmacodynamic additive effects
   Increased risk of hypoglycemia Drug Num:  25
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0009
 
Acarbose
 
C25H43NO18
 
41774 
Minor    Inter Info   
[4], [5], [6]
D0013
 
Acetohexamide
 
C15H20N2O4S
 
1989 
Minor    Inter Info   
[4], [5], [6]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Minor    Inter Info   
[4], [5], [6]
D0727
 
Glimepiride
 
C24H34N4O5S
 
3476 
Minor    Inter Info   
[4], [5], [6]
D0728
 
Glipizide
 
C21H27N5O4S
 
3478 
Minor    Inter Info   
[4], [5], [6]
D0730
 
Glyburide
 
C23H28ClN3O5S
 
3488 
Minor    Inter Info   
[4], [5], [6]
D0807
 
Insulin aspart (aspart protamine)
 
C256H381N65O79S6
 
118984445 
Minor    Inter Info   
[4], [5], [6]
D0808
 
Insulin aspart (aspart)
 
C256H381N65O79S6
 
118984445 
Minor    Inter Info   
[4], [5], [6]
D0809
 
Insulin degludec
 
C274H411N65O81S6
 
118984462 
Minor    Inter Info   
[4], [5], [6]
D0810
 
Insulin detemir
 
C267H402N64O76S6
 
16137271 
Minor    Inter Info   
[4], [5], [6]
D0811
 
Insulin glargine
 
C267H404N72O78S6
 
118984454 
Minor    Inter Info   
[4], [5], [6]
D0812
 
Insulin glulisine
 
C258H384N64O78S6
 
16136701 
Minor    Inter Info   
[4], [5], [6]
D0813
 
Insulin human
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0814
 
Insulin human (inhalation, rapid acting)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0815
 
Insulin human (isophane)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0816
 
Insulin human (regular)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0817
 
Insulin human (zinc extended)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0818
 
Insulin human (zinc)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0819
 
Insulin lispro
 
C257H389N65O77S6
 
16132438 
Minor    Inter Info   
[4], [5], [6]
D0820
 
Insulin lispro (protamine)
 
C257H389N65O77S6
 
16132438 
Minor    Inter Info   
[4], [5], [6]
D1064
 
Miglitol
 
C8H17NO5
 
441314 
Minor    Inter Info   
[4], [5], [6]
D1112
 
Nateglinide
 
C19H27NO3
 
5311309 
Minor    Inter Info   
[4], [5], [6]
D1392
 
Repaglinide
 
C27H36N2O4
 
65981 
Minor    Inter Info   
[4], [5], [6]
D1601
 
Tolazamide
 
C14H21N3O3S
 
5503 
Minor    Inter Info   
[4], [5], [6]
D1603
 
Tolbutamide
 
C12H18N2O3S
 
5505 
Minor    Inter Info   
[4], [5], [6]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0929
 
Linaclotide
 
C59H79N15O21S6
 
16158208 
Minor    Inter Info   
[7], [8]
References
1 Cerner Multum, Inc. "Australian Product Information.".
2 Multum Information Services, Inc. Expert Review Panel.
3 Product Information. Metamucil (psyllium). Procter and Gamble Pharmaceutic, Cincinnati, OH.
4 Anderson JW, Allgood LD, Turner J, Oeltgen PR, Daggy BP "Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia." Am J Clin Nutr 70 (1999): 466-73. [PMID: 10500014]
5 Fugh-Berman A "Herb-drug interactions." Lancet 355 (2000): 134-8. [PMID: 10675182]
6 Jenkins DJ, Wolever TM, Leeds AR, et al "Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity." Br Med J 1 (1978): 1392-4. [PMID: 647304]
7 EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".
8 Product Information. Linzess (linaclotide). Forest Pharmaceuticals, St. Louis, MO.