Details of Drug

Details of Drug

 Drug General Information (ID: D1177)
  Drug Name
Ombitasvir
  Drug Type Small molecule
  Drug Synonymous
HCV therapeutic, Abbott
    Click to Show/Hide
  Disease Class 1E50-1E51: Hepatitis virus infection
  Therapeutic Class Antiviral Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C50H67N7O8
  InChI 1S/C50H67N7O8/c1-30(2)42(53-48(62)64-8)46(60)55-28-10-12-40(55)44(58)51-35-20-14-32(15-21-35)38-26-27-39(57(38)37-24-18-34(19-25-37)50(5,6)7)33-16-22-36(23-17-33)52-45(59)41-13-11-29-56(41)47(61)43(31(3)4)54-49(63)65-9/h14-25,30-31,38-43H,10-13,26-29H2,1-9H3,(H,51,58)(H,52,59)(H,53,62)(H,54,63)/t38-,39-,40-,41-,42-,43-/m0/s1
  InChIKey PIDFDZJZLOTZTM-KHVQSSSXSA-N
  Canonical SMILES CC(C)C(C(=O)N1CCCC1C(=O)NC2=CC=C(C=C2)C3CCC(N3C4=CC=C(C=C4)C(C)(C)C)C5=CC=C(C=C5)NC(=O)C6CCCN6C(=O)C(C(C)C)NC(=O)OC)NC(=O)OC
  External Link
Pubchem ID 54767916
CAS Number 1258226-87-7
CHEBI ID 85183
TTD ID D0LF5Q
INTEDE ID DR1193
VARIDT ID DR01311

Drug-Drug Interaction Network
  Sunburst Graph
AM002  Affected cellular transport
AM004  Affected intra/extra-hepatic metabolism
BM010  Transporter inhibition
BM022  CYP450 enzyme induction
  Relation Graph
 Full list of drugs interacting with Ombitasvir
      Affected cellular transport
   Transporter inhibition Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1539
 
Tedizolid
 
C17H15FN6O3
 
11234049 
Moderate    Inter Info   
[1], [4], [5]
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme induction Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0255
 
Carbamazepine
 
C15H12N2O
 
2554 
Major    Inter Info   
[1], [2], [3]
D0697
 
Fosphenytoin
 
C16H15N2O6P
 
56339 
Major    Inter Info   
[1], [2], [3]
D1283
 
Phenytoin
 
C15H12N2O2
 
1775 
Major    Inter Info   
[1], [2], [3]
References
1 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2 Product Information. Viekira Pak (dasabuvir/ombitasvir/paritaprevir/ritonavir). AbbVie US LLC, North Chicago, IL.
3 Product Information. Xtandi (enzalutamide). Astellas Pharma US, Inc, Deerfield, IL.
4 Product Information. Sivextro (tedizolid). Cubist Pharmaceuticals Inc, Lexington, MA.
5 Product Information. Venclexta (venetoclax). AbbVie US LLC, North Chicago, IL.