Details of Drug

Details of Drug

 Drug General Information (ID: D1152)
  Drug Name
Norelgestromin
  Drug Type Small molecule
  Drug Synonymous
Norelgestromin; 53016-31-2; UNII-UM2XKY25DH; UM2XKY25DH; Evra; Ortho Evra; RWJ-10553; Norgestimate metabolite Norelgestromin; 17-Desacetyl Norgestimate; DEACETYLNORGESTIMATE (25 MG) ((E)- AND (Z)-17-DEACETYL NORGESTIMATE MIXTURE); C21H29NO2; Deacetylnorgestimate; anti-Norelgestromin; NCGC00168787-01; ((E)-Norelgestromin); Norelgestromin, (E)-; Norelgestromin (USP/INN); DSSTox_CID_26788; DSSTox_RID_81906; DSSTox_GSID_46788; (E)-17-Deacetylnorgestimate; Norgestimate impurity C [EP]; SCHEMBL3163347; 17-Deacetylnorgestimate, (E)-; CHEMBL1200807; DTXSID9046788; CHEBI:135398; HY-G0018; Tox21_112647; 3046AH; BDBM50103633; AKOS015917579; NCGC00485891-01; CAS-53016-31-2; D05205; UNII-R0TAY3X631 component ISHXLNHNDMZNMC-VTKCIJPMSA-N; (3E)-13beta-Ethyl-3-(hydroxyimino)-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol; 18,19-Dinorpregn-4-en-20-yn-3-one, 13-ethyl-17-hydroxy-, oxime, (3E,17alpha)-; (3E,8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-3-hydroxyimino-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol; (8R,9S,10R,13S,14S,17R,E)-13-ethyl-17-ethynyl-17-hydroxy-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3(2H)-one oxime; 74183-55-4
    Click to Show/Hide
  Therapeutic Class Hormones/Antineoplastics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C21H29NO2
  InChI InChI=1S/C21H29NO2/c1-3-20-11-9-17-16-8-6-15(22-24)13-14(16)5-7-18(17)19(20)10-12-21(20,23)4-2/h2,13,16-19,23-24H,3,5-12H2,1H3/b22-15+/t16-,17+,18+,19-,20-,21-/m0/s1
  InChIKey ISHXLNHNDMZNMC-VTKCIJPMSA-N
  Canonical SMILES CC[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C#C)O)CCC4=C/C(=N/O)/CC[C@H]34
  External Link
Pubchem ID 9568628

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
AM007  Pharmacodynamic antagonistic effects
BM017  CYP450 enzyme inhibition
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Norelgestromin
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0426
 
Darunavir
 
C27H37N3O7S
 
213039 
Moderate    Inter Info   
[4], [2]
D0906
 
Letermovir
 
C29H28F4N4O4
 
45138674 
Moderate    Inter Info   
[5], [1], [6]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1894
 
Sugammadex
 
C72H112O48S8
 
6918585 
Major    Inter Info   
[1], [2], [3]
D1664
 
Ulipristal
 
C28H35NO3
 
13559281 
Moderate    Inter Info   
[1], [7], [2]
References
1 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2 Schubert W, Eriksson U, Edgar B, Cullberg G, Hedner T "Flavonoids in grapefruit juice inhibit the in vitro hepatic metabolism of 17B-estradiol." Eur J Drug Metab Pharmacokinet 20 (1995): 219-24. [PMID: 8751044]
3 Product Information. Bridion (sugammadex). Merck &amp Company Inc, Whitehouse Station, NJ.
4 Product Information. Prezista (darunavir). Ortho Biotech Inc, Bridgewater, NJ.
5 Cerner Multum, Inc. "Australian Product Information.".
6 Product Information. Prevymis (letermovir). Merck &amp Company Inc, Whitehouse Station, NJ.
7 Product Information. ella (ulipristal). Afaxys Inc., Charleston, SC.