Details of Drug

Drug General Information (ID: D1142)
Drug Name	Nitazoxanide
Drug Type	Small molecule
Drug Synonymous	Alinia; Colufase; Cryptaz; Daxon; Heliton; Nitazoxanid; Nitazoxanida; Nitazoxanidum; Taenitaz; Tizoxanide glucuronide; AZT + Nitazoxanide; Alinia (TN); Annita (TN); Azt+ nitazoxanide; Daxon (TN); Dexidex (TN); Kidonax (TN); Nitax (TN); Nitazox (TN); Nitazoxanida [INN-Spanish]; Nitazoxanide [USAN:INN]; Nitazoxanidum [INN-Latin]; Pacovanton (TN); Paramix (TN); Phavic-1; Zox (TN); Nitazoxanide (USAN/INN); Daxon, Dexidex, Kidonax, Pacovanton, Paramix, Nitax, Zox, Nitazoxanide Click to Show/Hide
Disease Class	ME05: Bowel habit change
Therapeutic Class	Antiparasitic Agents
Structure
Structure	3D Structure		2D Structure
Formula	C12H9N3O5S
InChI	1S/C12H9N3O5S/c1-7(16)20-9-5-3-2-4-8(9)11(17)14-12-13-6-10(21-12)15(18)19/h2-6H,1H3,(H,13,14,17)
InChIKey	YQNQNVDNTFHQSW-UHFFFAOYSA-N
Canonical SMILES	CC(=O)OC1=CC=CC=C1C(=O)NC2=NC=C(S2)[N+](=O)[O-]
External Link
	Pubchem ID	41684
	CAS Number	55981-09-4
	CHEBI ID	94807
	TTD ID	D08EBN

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM003 Affected organization distribution BM013 Competitive binding of plasma proteins
Relation Graph

Full list of drugs interacting with Nitazoxanide
Affected organization distribution
	Competitive binding of plasma proteins					Drug Num: 22
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0013		Acetohexamide	C15H20N2O4S	1989	Moderate		Inter Info	[1]
D0481		Dicoumarol	C19H12O6	54676038	Moderate		Inter Info	[2], [1]
D0727		Glimepiride	C24H34N4O5S	3476	Moderate		Inter Info	[1]
D0927		Lidocaine	C14H22N2O	3676	Moderate		Inter Info	[1]
D0951		Lorazepam	C15H10Cl2N2O2	3958	Moderate		Inter Info	[1]
D0325		Chlorpropamide	C10H13ClN2O3S	2727	Moderate		Inter Info	[1]
D0365		Clorazepic acid	C16H11ClN2O3	2809	Moderate		Inter Info	[2], [1]
D0473		Diazepam	C16H13ClN2O	3016	Moderate		Inter Info	[1]
D0604		Estazolam	C16H11ClN4	3261	Moderate		Inter Info	[1]
D0679		Flurazepam	C21H23ClFN3O	3393	Moderate		Inter Info	[1]
D0728		Glipizide	C21H27N5O4S	3478	Moderate		Inter Info	[1]
D0730		Glyburide	C23H28ClN3O5S	3488	Moderate		Inter Info	[1]
D1025		Methotrexate	C20H22N8O5	126941	Moderate		Inter Info	[1]
D1060		Midazolam	C18H13ClFN3	4192	Moderate		Inter Info	[1]
D1197		Oxazepam	C15H11ClN2O2	4616	Moderate		Inter Info	[1]
D1367		Quazepam	C17H11ClF4N2S	4999	Moderate		Inter Info	[1]
D1601		Tolazamide	C14H21N3O3S	5503	Moderate		Inter Info	[1]
D1603		Tolbutamide	C12H18N2O3S	5505	Moderate		Inter Info	[1]
D1711		Warfarin	C19H16O4	54678486	Moderate		Inter Info	[1]
D1283		Phenytoin	C15H12N2O2	1775	Moderate		Inter Info	[1]
D1547		Temazepam	C16H13ClN2O2	5391	Moderate		Inter Info	[1]
D1677		Valproic acid	C8H16O2	3121	Moderate		Inter Info	[1]

References
1	Product Information. Alinia (nitazoxanide). Romark Laboratories L.C., Tampa, FL.
2	Guo LQ, Yamazoe Y "Inhibition of cytochrome P450 by furanocoumarins in grapefruit juice and herbal medicines." Acta Pharmacol Sin 25 (2004): 129-36. [PMID: 14769198]