Details of Drug

Drug General Information (ID: D1113)
Drug Name	Naxitamab
Drug Type	Monoclonal antibody
Disease Class	2B51: Osteosarcoma; 2D11: Adrenal cancer
Therapeutic Class	Antineoplastics
External Link
External Link	TTD ID	D0HI5D

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM006 Pharmacodynamic additive effects AM007 Pharmacodynamic antagonistic effects BM043 Additive immunosuppressive effects BM044 Additive myelosuppressive effects BM074 Increased risk of peripheral neuropathy BM100 Antagonize the effect of vaccine/toxoid BM105 Antagonize the effect of probiotics BM106 Diminish the response to diagnostic skin test antigens BM107 Attenuated pharmacological effects (Unspecific) BM110 Antagonize the effects of immunosuppressants
Relation Graph

Full list of drugs interacting with Naxitamab
Pharmacodynamic additive effects
	Additive immunosuppressive effects					Drug Num: 77
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0023		Adalimumab	NA	NA	Major		Inter Info	[1], [2], [3], [4], [5], [6]
D0146		Baricitinib	C16H17N7O2S	44205240	Major		Inter Info	[7], [8], [9]
D0304		Certolizumab pegol	NA	NA	Major		Inter Info	[1], [5], [6]
D0348		Cladribine	C10H12ClN5O3	20279	Major		Inter Info	[8], [10]
D0614		Etanercept	NA	NA	Major		Inter Info	[1], [2], [3], [4], [5], [6]
D0661		Fingolimod	C19H33NO2	107970	Major		Inter Info	[15]
D0736		Golimumab	NA	NA	Major		Inter Info	[1], [2], [3], [4], [5], [6]
D0802		Infliximab	NA	NA	Major		Inter Info	[1], [2], [3], [4], [5], [6]
D0900		Leflunomide	C12H9F3N2O2	3899	Major		Inter Info	[16], [17]
D1111		Natalizumab	NA	NA	Major		Inter Info	[21]
D1211		Ozanimod	C23H24N4O3	52938427	Major		Inter Info	[8], [22]
D1474		Siponimod	C29H35F3N2O3	44599207	Major		Inter Info	[7], [24]
D1556		Teriflunomide	C12H9F3N2O2	54684141	Major		Inter Info	[16], [17]
D1600		Tofacitinib	C16H20N6O	9926791	Major		Inter Info	[28]
D1666		Upadacitinib	C17H19F3N6O	58557659	Major		Inter Info	[29]
D0030		Aldesleukin	NA	NA	Moderate		Inter Info	[8], [30], [31]
D0032		Alefacept	NA	NA	Moderate		Inter Info	[25], [32], [33]
D0033		Alemtuzumab	NA	NA	Moderate		Inter Info	[34]
D0085		Anakinra	C20H23N5O7S2	146171046	Moderate		Inter Info	[37], [38], [39]
D0136		Azathioprine	C9H7N7O2S	2265	Moderate		Inter Info	[7], [8]
D0157		Bendamustine	C16H21Cl2N3O2	65628	Moderate		Inter Info	[8], [30], [31]
D0190		Bleomycin	C55H84N17O21S3+	5360373	Moderate		Inter Info	[8], [30], [31]
D0223		Busulfan	C6H14O6S2	2478	Moderate		Inter Info	[8], [30], [31]
D0246		Canakinumab	NA	NA	Moderate		Inter Info	[37], [38], [39]
D0249		Capecitabine	C15H22FN3O6	60953	Moderate		Inter Info	[8], [30], [31]
D0264		Carmustine	C5H9Cl2N3O2	2578	Moderate		Inter Info	[8], [30], [31]
D0312		Chlorambucil	C14H19Cl2NO2	2708	Moderate		Inter Info	[8], [30], [31]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Moderate		Inter Info	[7], [8], [47]
D0314		Chloramphenicol (ophthalmic)	C11H12Cl2N2O5	5959	Moderate		Inter Info	[7], [8], [47]
D0357		Clofarabine	C10H11ClFN5O3	119182	Moderate		Inter Info	[8], [30], [31]
D0400		Cyclophosphamide	C7H15Cl2N2O2P	2907	Moderate		Inter Info	[8], [30], [31]
D0404		Cytarabine	C9H13N3O5	6253	Moderate		Inter Info	[8], [30], [31]
D0405		Cytarabine (liposomal)	C9H13N3O5	6253	Moderate		Inter Info	[8], [30], [31]
D0407		Dacarbazine	C6H10N6O	135398738	Moderate		Inter Info	[8], [30], [31]
D0410		Dactinomycin	C62H86N12O16	457193	Moderate		Inter Info	[8], [30], [31]
D0429		Daunorubicin	C27H29NO10	30323	Moderate		Inter Info	[8], [30], [31]
D0430		Daunorubicin (liposomal)	C27H29NO10	30323	Moderate		Inter Info	[8], [30], [31]
D0431		Decitabine	C8H12N4O4	451668	Moderate		Inter Info	[8], [30], [31]
D0443		Denosumab	NA	NA	Moderate		Inter Info	[48]
D0499		Dimethyl fumarate	C6H8O4	637568	Moderate		Inter Info	[49]
D0507		Diroximel fumarate	C11H13NO6	73330464	Moderate		Inter Info	[49]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[8], [30], [31]
D0584		Epirubicin	C27H29NO11	41867	Moderate		Inter Info	[8], [30], [31]
D0666		Floxuridine	C9H11FN2O5	5790	Moderate		Inter Info	[8], [30], [31]
D0675		Fluorouracil	C4H3FN2O2	3385	Moderate		Inter Info	[8], [30], [31]
D0714		Gemcitabine	C9H11F2N3O4	60750	Moderate		Inter Info	[8], [30], [31]
D0780		Hydroxyurea	CH4N2O2	3657	Moderate		Inter Info	[8], [30], [31]
D0788		Idarubicin	C26H27NO9	42890	Moderate		Inter Info	[8], [30], [31]
D0790		Ifosfamide	C7H15Cl2N2O2P	3690	Moderate		Inter Info	[8], [30], [31]
D0793		Imatinib	C29H31N7O	5291	Moderate		Inter Info	[8], [30], [31]
D0851		Isatuximab	NA	NA	Moderate		Inter Info	[8], [30], [31]
D0945		Lomustine	C9H16ClN3O2	3950	Moderate		Inter Info	[8], [30], [31]
D0962		Lurbinectedin	C41H44N4O10S	57327016	Moderate		Inter Info	[8], [30], [31]
D0986		Mechlorethamine	C5H11Cl2N	4033	Moderate		Inter Info	[8], [30], [31]
D0996		Melphalan	C13H18Cl2N2O2	460612	Moderate		Inter Info	[8], [30], [31]
D1007		Mercaptopurine	C5H4N4S	667490	Moderate		Inter Info	[8], [30], [31]
D1025		Methotrexate	C20H22N8O5	126941	Moderate		Inter Info	[8], [30], [31]
D1077		Mitomycin	C15H18N4O5	5746	Moderate		Inter Info	[8], [30], [31]
D1079		Mitoxantrone	C22H28N4O6	4212	Moderate		Inter Info	[8], [30], [31]
D1085		Monomethyl fumarate	C5H6O4	5369209	Moderate		Inter Info	[49]
D1140		Niraparib	C19H20N4O	24958200	Moderate		Inter Info	[58]
D1162		Ocrelizumab	NA	NA	Moderate		Inter Info	[59]
D1167		Olaparib	C24H23FN4O3	23725625	Moderate		Inter Info	[8], [60]
D1855		Palifermin	NA	NA	Moderate		Inter Info	[61]
D1241		Pemetrexed	C20H21N5O6	135410875	Moderate		Inter Info	[8], [30], [31]
D1403		Rilonacept	NA	NA	Moderate		Inter Info	[37], [38], [39]
D1422		Roflumilast	C17H14Cl2F2N2O3	449193	Moderate		Inter Info	[8], [64]
D1434		Ruxolitinib	C17H18N6	25126798	Moderate		Inter Info	[8], [30], [31]
D1508		Streptozocin	C8H15N3O7	29327	Moderate		Inter Info	[8], [30], [31]
D1509		Strontium chloride Sr-89	Cl2Sr	5388879	Moderate		Inter Info	[7], [8], [65]
D1548		Temozolomide	C6H6N6O2	5394	Moderate		Inter Info	[8], [30], [31]
D1575		Thiotepa	C6H12N3PS	5453	Moderate		Inter Info	[8], [30], [31]
D1578		Tiagabine	C20H25NO2S2	60648	Moderate		Inter Info	[8], [30], [31]
D1589		Tioguanine	C5H5N5S	2723601	Moderate		Inter Info	[8], [30], [31]
D1610		Topotecan	C23H23N3O5	60700	Moderate		Inter Info	[67]
D1671		Ustekinumab	NA	NA	Moderate		Inter Info	[71]
D1720		Zidovudine	C10H13N5O4	35370	Moderate		Inter Info	[7], [8], [72]
	Additive myelosuppressive effects					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0370		Clozapine	C18H19ClN4	135398737	Major		Inter Info	[8], [11], [12]
D0433		Deferiprone	C7H9NO2	2972	Major		Inter Info	[7], [13], [14]
D1443		Samarium (153Sm) lexidronam	Sm	23951	Major		Inter Info	[23]
D0710		Ganciclovir	C9H13N5O4	135398740	Moderate		Inter Info	[7], [8], [53], [54]
D1676		Valganciclovir	C14H22N6O5	135413535	Moderate		Inter Info	[7], [8], [53], [54]
	Increased risk of peripheral neuropathy					Drug Num: 68
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[35], [30], [36]
D0120		Atorvastatin	C33H35FN2O5	60823	Moderate		Inter Info	[35], [30], [36]
D0126		Auranofin	C20H34AuO9PS	24199313	Moderate		Inter Info	[35], [30], [36]
D0162		Benznidazole	C12H12N4O3	31593	Moderate		Inter Info	[35], [30], [36]
D0193		Bortezomib	C19H25BN4O4	387447	Moderate		Inter Info	[42], [43], [44]
D0199		Brentuximab vedotin	NA	NA	Moderate		Inter Info	[35], [45], [46]
D0227		Cabazitaxel	C45H57NO14	9854073	Moderate		Inter Info	[35], [30], [36]
D0260		Carboplatin	C6H12N2O4Pt	426756	Moderate		Inter Info	[35], [30], [36]
D0261		Carfilzomib	C40H57N5O7	11556711	Moderate		Inter Info	[35], [30], [36]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[35], [30], [36]
D0344		Cisplatin	Cl2H6N2Pt	5702198	Moderate		Inter Info	[35], [30], [36]
D0380		Colchicine	C22H25NO6	6167	Moderate		Inter Info	[35], [30], [36]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Moderate		Inter Info	[35], [30], [36]
D0419		Dapsone	C12H12N2O2S	2955	Moderate		Inter Info	[35], [30], [36]
D0483		Didanosine	C10H12N4O3	135398739	Moderate		Inter Info	[35], [30], [36]
D0496		Diiodohydroxyquinoline	C9H5I2NO	3728	Moderate		Inter Info	[35], [30], [36]
D0501		Dinutuximab	NA	NA	Moderate		Inter Info	[35], [30], [36]
D0509		Disulfiram	C10H20N2S4	3117	Moderate		Inter Info	[35], [30], [36]
D0511		Docetaxel	C43H53NO14	148124	Moderate		Inter Info	[35], [30], [36]
D0560		Elotuzumab	NA	NA	Moderate		Inter Info	[35], [30], [36]
D0571		Enfortumab vedotin	NA	NA	Moderate		Inter Info	[35], [30], [36]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[35], [30], [36]
D0616		Ethambutol	C10H24N2O2	14052	Moderate		Inter Info	[35], [30], [36]
D1731		Ethionamide	C8H10N2S	2761171	Moderate		Inter Info	[35], [30], [36]
D0627		Etoposide	C29H32O13	36462	Moderate		Inter Info	[35], [30], [36]
D0628		Etravirine	C20H15BrN6O	193962	Moderate		Inter Info	[35], [30], [36]
D0669		Fludarabine	C10H12FN5O4	657237	Moderate		Inter Info	[35], [30], [36]
D0686		Fluvastatin	C24H26FNO4	446155	Moderate		Inter Info	[35], [30], [36]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[35], [30], [36]
D0822		Interferon alfa-2b	C16H17Cl3I2N3NaO5S	71306834	Moderate		Inter Info	[35], [30], [36]
D0823		Interferon alfacon-1	NA	NA	Moderate		Inter Info	[35], [30], [36]
D0841		Ipilimumab	NA	NA	Moderate		Inter Info	[35], [30], [36]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[35], [30], [36]
D0873		Ixabepilone	C27H42N2O5S	6445540	Moderate		Inter Info	[35], [30], [36]
D0874		Ixazomib	C14H19BCl2N2O4	25183872	Moderate		Inter Info	[35], [30], [36]
D0918		Levodopa	C9H11NO4	6047	Moderate		Inter Info	[35], [30], [36]
D0933		Linezolid	C16H20FN3O4	441401	Moderate		Inter Info	[35], [30], [36]
D0956		Lovastatin	C24H36O5	53232	Moderate		Inter Info	[35], [30], [36]
D1051		Metronidazole	C6H9N3O3	4173	Moderate		Inter Info	[35], [30], [36]
D1118		Nelarabine	C11H15N5O5	3011155	Moderate		Inter Info	[35], [30], [36]
D1145		Nitrofurantoin	C8H6N4O5	6604200	Moderate		Inter Info	[35], [30], [36]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[35], [30], [36]
D1212		Paclitaxel	C47H51NO14	36314	Moderate		Inter Info	[35], [30], [36]
D1213		Paclitaxel (protein-bound)	C47H51NO14	36314	Moderate		Inter Info	[35], [30], [36]
D1237		Peginterferon alfa-2a	NA	NA	Moderate		Inter Info	[35], [30], [36]
D1238		Peginterferon alfa-2b	NA	NA	Moderate		Inter Info	[35], [30], [36]
D1301		Pitavastatin	C25H24FNO4	5282452	Moderate		Inter Info	[35], [30], [36]
D1306		Polatuzumab vedotin	NA	NA	Moderate		Inter Info	[35], [30], [36]
D1312		Pomalidomide	C13H11N3O4	134780	Moderate		Inter Info	[35], [30], [36]
D1313		Ponatinib	C29H27F3N6O	24826799	Moderate		Inter Info	[35], [30], [36]
D1329		Pravastatin	C23H36O7	54687	Moderate		Inter Info	[35], [30], [36]
D1430		Rosuvastatin	C22H28FN3O6S	446157	Moderate		Inter Info	[35], [30], [36]
D1452		Secnidazole	C7H11N3O3	71815	Moderate		Inter Info	[35], [30], [36]
D1473		Simvastatin	C25H38O5	54454	Moderate		Inter Info	[35], [30], [36]
D1479		Sodium aurothiomalate	C4H3AuNa2O4S	22318	Moderate		Inter Info	[35], [30], [36]
D1504		Stavudine	C10H12N2O4	18283	Moderate		Inter Info	[35], [30], [36]
D1543		Telbivudine	C10H14N2O5	159269	Moderate		Inter Info	[35], [30], [36]
D1551		Teniposide	C32H32O13S	452548	Moderate		Inter Info	[35], [30], [36]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[42], [7], [8], [66]
D1587		Tinidazole	C8H13N3O4S	5479	Moderate		Inter Info	[35], [30], [36]
D1599		Tocilizumab	NA	NA	Moderate		Inter Info	[35], [30], [36]
D1615		Trabectedin	C39H43N3O11S	108150	Moderate		Inter Info	[35], [30], [36]
D1623		Trastuzumab emtansine	NA	NA	Moderate		Inter Info	[35], [30], [36]
D1697		Vinblastine	C46H58N4O9	13342	Moderate		Inter Info	[35], [30], [36]
D1698		Vincristine	C46H56N4O10	5978	Moderate		Inter Info	[35], [30], [36]
D1699		Vincristine (liposome)	C46H56N4O10	5978	Moderate		Inter Info	[35], [30], [36]
D1700		Vinorelbine	C45H54N4O8	5311497	Moderate		Inter Info	[35], [30], [36]
D1714		Zafirlukast	C31H33N3O6S	5717	Moderate		Inter Info	[35], [30], [36]
Pharmacodynamic antagonistic effects
	Antagonize the effect of vaccine/toxoid					Drug Num: 17
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1839		Measles virus vaccine live attenuated	NA	NA	Major		Inter Info	[18], [19], [20]
D1881		Rotavirus vaccine	NA	NA	Major		Inter Info	[18], [19], [20]
D1882		Rubella virus vaccine	NA	NA	Major		Inter Info	[18], [19], [20]
D1890		Smallpox (Vaccinia) Vaccine, Live	NA	NA	Major		Inter Info	[25], [7], [26]
D1897		Talimogene laherparepvec	NA	NA	Major		Inter Info	[27]
D1914		Typhoid vaccine (live)	NA	NA	Major		Inter Info	[18], [19], [20]
D1920		Varicella Zoster Vaccine (Recombinant)	NA	NA	Major		Inter Info	[18], [19], [20]
D1922		Yellow Fever Vaccine	NA	NA	Major		Inter Info	[18], [19], [20]
D0089		Anthrax vaccine	NA	NA	Moderate		Inter Info	[25], [40], [41]
D0366		Clostridium tetani toxoid antigen (formaldehyde inactivated)	NA	NA	Moderate		Inter Info	[25], [40], [41]
D0755		Hepatitis A Vaccine	NA	NA	Moderate		Inter Info	[25], [40], [41]
D0756		Hepatitis B Vaccine (Recombinant)	NA	NA	Moderate		Inter Info	[25], [40], [41]
D0767		Human papillomavirus type 11 L1 capsid protein antigen	NA	NA	Moderate		Inter Info	[25], [40], [41]
D0803		Influenza A virus A/California/7/2009 (H1N1)-like antigen (propiolactone inactivated)	NA	NA	Moderate		Inter Info	[25], [40], [41]
D0999		Meningococcal polysaccharide vaccine group C	NA	NA	Moderate		Inter Info	[25], [40], [41]
D0804		Influenza A virus A/Vietnam/1194/2004 (H5N1) antigen (formaldehyde inactivated)	NA	NA	Moderate		Inter Info	[25], [40], [41]
D1307		Poliovirus type 1 antigen (formaldehyde inactivated)	NA	NA	Moderate		Inter Info	[25], [40], [41]
	Antagonize the effect of probiotics					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1827		Lactobacillus acidophilus	NA	NA	Moderate		Inter Info	[55], [56], [57]
	Diminish the response to diagnostic skin test antigens					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1912		Trichophyton mentagrophytes	NA	NA	Moderate		Inter Info	[68], [69], [70]
D1913		Tuberculin purified protein derivative	NA	NA	Moderate		Inter Info	[68], [69], [70]
	Attenuated pharmacological effects (Unspecific)					Drug Num: 3
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0659		Filgrastim	NA	NA	Moderate		Inter Info	[50], [51], [52]
D1235		Pegfilgrastim	C27H46N4O19	70683024	Moderate		Inter Info	[62], [63]
D1446		Sargramostim	NA	NA	Moderate		Inter Info	[50], [51], [52]
	Antagonize the effects of immunosuppressants					Drug Num: 5
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0545		Echinacea	NA	NA	Minor		Inter Info	[73], [74], [75]
D1722		Zinc acetate	C4H6O4Zn	11192	Minor		Inter Info	[73], [74], [75]
D1723		Zinc chloride	Cl2Zn	5727	Minor		Inter Info	[73], [74], [75]
D1724		Zinc gluconate	C12H22O14Zn	443445	Minor		Inter Info	[73], [74], [75]
D1725		Zinc sulfate	O4SZn	24424	Minor		Inter Info	[73], [74], [75]

References
1	Product Information. Cimzia (certolizumab). UCB Pharma Inc, Smyrna, GA.
2	Product Information. Enbrel (etanercept). Wyeth-Ayerst Laboratories, Philadelphia, PA.
3	Product Information. Humira (adalimumab). Abbott Pharmaceutical, Abbott Park, IL.
4	Product Information. Remicade (infliximab). Centocor Inc, Malvern, PA.
5	Product Information. Simponi (golimumab). Centocor Inc, Malvern, PA.
6	FDA. U.S. Food and Drug Administration "FDA Drug Safety Communication: Drug labels for the Tumor Necrosis Factor-alpha (TNFa) blockers now include warnings about infection with Legionella and Listeria bacteria. ".
7	Cerner Multum, Inc. "Australian Product Information.".
8	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
9	Product Information. Olumiant (baricitinib). Lilly, Eli and Company, Indianapolis, IN.
10	Product Information. Leustatin (cladribine). Ortho Biotech Inc, Raritan, NJ.
11	Product Information. Clozaril (clozapine). Novartis Pharmaceuticals, East Hanover, NJ.
12	Canadian Pharmacists Association "e-CPS."
13	Product Information. Ferriprox (deferiprone). ApoPharma USA Inc, Rockville, MD.
14	EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports."
15	Product Information. Gilenya (fingolimod). Novartis Pharmaceuticals, East Hanover, NJ.
16	Product Information. Arava (leflunomide). Hoechst Marion-Roussel Inc, Kansas City, MO.
17	Product Information. Aubagio (teriflunomide). Genzyme Corporation, Cambridge, MA.
18	Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds. "Harrison's Principles of Internal Medicine. 14th ed." New York, NY: McGraw-Hill Health Professionals Division (1998).
19	Product Information. Attenuvax (measles virus vaccine, live, attenuated). Merck &amp Co, Inc, West Point, PA.
20	Product Information. YF-Vax (yellow fever vaccine). sanofi pasteur, Swiftwater, PA.
21	Product Information. Tysabri (natalizumab). Elan Pharmaceutical/Athena Neurosciences Inc, South San Francisco, CA.
22	Product Information. Zeposia (ozanimod). Celgene Corporation, Summit, NJ.
23	Product Information. Quadramet (samarium sm 153 lexidronam) Berlex Laboratories, Richmond, CA.
24	Product Information. Mayzent (siponimod). Novartis Pharmaceuticals, East Hanover, NJ.
25	CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]
26	Product Information. Dryvax (smallpox vaccine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
27	Product Information. Imlygic (talimogene laherparepvec). Amgen USA, Thousand Oaks, CA.
28	Product Information. Xeljanz (tofacitinib). Pfizer U.S. Pharmaceuticals Group, New York, NY.
29	Product Information. Rinvoq (upadacitinib). AbbVie US LLC, North Chicago, IL.
30	EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".
31	Product Information. Fluorouracil injection (fluorouracil). Roche Laboratories, Nutley, NJ.
32	Product Information. Amevive (alefacept). Biogen, Cambridge, MA.
33	Product Information. Lonsurf (tipiracil-trifluridine). Taiho Oncology, Inc., Princeton, NJ.
34	Product Information. Campath (alemtuzumab) Berlex, Richmond, CA.
35	Carrion C, Espinosa E, Herrero A, Garcia B "Possible vincristine-isoniazid interaction." Ann Pharmacother 29 (1995): 201. [PMID: 7756727]
36	Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online."
37	Product Information. Arcalyst (rilonacept). Regeneron Pharmaceuticals Inc, Tarrytown, NY.
38	Product Information. Ilaris (canakinumab). Novartis Pharmaceuticals, East Hanover, NJ.
39	Product Information. Kineret (anakinra). Amgen, Thousand Oaks, CA.
40	Product Information. Imovax Rabies (rabies vaccine). sanofi pasteur, Swiftwater, PA.
41	Department of Health. National Health Service "Immunisation Against Infectious Disease - "The Green Book". Chapter 6: Contraindications and special considerations.".
42	Argov Z, Mastaglia FL "Drug-induced peripheral neuropathies." Br Med J 1 (1979): 663-6. [PMID: 219931]
43	Cavaletti G, Jakubowiak AJ "Peripheral neuropathy during bortezomib treatment of multiple myeloma: a review of recent studies." Leuk Lymphoma 51 (2010): 1178-87. [PMID: 20497001]
44	Product Information. Velcade (bortezomib). Millennium Pharmaceuticals Inc, Cambridge, MA.
45	Product Information. Adcetris (brentuximab vedotin). Seattle Genetics Inc, Bothell, WA.
46	Product Information. Danyelza (naxitamab). Y-mAbs Therapeutics, New York, NY.
47	Sim SM, Back DJ, Breckenridge AM "The effect of various drugs on the glucuronidation of zidovudine (azidothymidine AZT) by human liver microsomes." Br J Clin Pharmacol 32 (1991): 17-21. [PMID: 1909542]
48	Product Information. Prolia (denosumab). Amgen USA, Thousand Oaks, CA.
49	Product Information. Vumerity (diroximel fumarate). Alkermes, Inc, Cambridge, MA.
50	Product Information. Granix (tbo-filgrastim). Teva Pharmaceuticals USA, North Wales, PA.
51	Product Information. Leukine (sargramostim). Immunex Corporation, Seattle, WA.
52	Product Information. Stemgen (ancestim) Amgen, Thousand Oaks, CA.
53	Product Information. Cytovene (ganciclovir). Genentech, South San Francisco, CA.
54	Product Information. Valcyte (valganciclovir) Roche Laboratories, Nutley, NJ.
55	Borriello SP, Hammes WP, Holzapfel W, et.al "Safety of probiotics that contain lactobacilli or bifidobacteria." Clin Infect Dis 36 (2003): 775-80. [PMID: 12627362]
56	Schlegel L, Lemerle S, Geslin P "Lactobacillus species as opportunistic pathogens in immunocompromised patients." Eur J Clin Microbiol Infect Dis 17 (1998): 887-8. [PMID: 10052559]
57	Salminen MK, Tynkkynen S, Rautelin H, et al. "Lactobacillus bacteremia during a rapid increase in probiotic use of Lactobacillus rhamnosus GG in Finland." Clin Infect Dis 35 (2002): 1155-60. [PMID: 12410474]
58	Product Information. Zejula (niraparib). Tesaro Inc., Waltham, MA.
59	Product Information. Ocrevus (ocrelizumab). Genentech, South San Francisco, CA.
60	Product Information. Lynparza (olaparib). Astra-Zeneca Pharmaceuticals, Wilmington, DE.
61	Product Information. Kepivance (palifermin). Shire US Inc, Florence, KY.
62	Product Information. Brukinsa (zanubrutinib). BeiGene USA, Inc, San Mateo, CA.
63	Product Information. Neulasta (pegfilgrastim). Amgen, Thousand Oaks, CA.
64	Product Information. Daxas (roflumilast). Nycomed Inc, Princeton, NJ.
65	Multum Information Services, Inc. Expert Review Panel.
66	Product Information. Thalomid (thalidomide). Celgene Corporation, Warren, NJ.
67	Product Information. Hycamtin (topotecan). SmithKline Beecham, Philadelphia, PA.
68	Product Information. Tuberculin PPD (Mantoux) (tuberculin purified protein derivative). Connaught Laboratories Ltd, Toronto, ON.
69	Product Information. Candin (candida albicans extract). Nielsen Biosciences Inc, San Diego, CA.
70	Product Information. Spherulin (coccidioidin skin test). ALK Laboratories Inc, Wallingford, CT.
71	Product Information. Stelara (ustekinumab). Centocor Inc, Malvern, PA.
72	Product Information. Retrovir (zidovudine). Glaxo Wellcome, Research Triangle Park, NC.
73	Izzo AA, Ernst E "Interactions between herbal medicines and prescribed drugs: a systematic review." Drugs 61 (2001): 2163-75. [PMID: 11772128]
74	Miller LG "Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions." Arch Intern Med 158 (1998): 2200-11. [PMID: 9818800]
75	Pepping J "Echinacea." Am J Health Syst Pharm 56 (1999): 121-2

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