Details of Drug

Details of Drug

 Drug General Information (ID: D1071)
  Drug Name
Minocycline (topical)
  Drug Type Small molecule
  Drug Synonymous
Borymycin; MINO; MIY; Minociclina; Minociclinum; Minocin; Minocline; Minocyclin; Minocyclinum; Minocycline Monohydrochloride; CL 59806; Lactoferrin B & Minocycline; Lactoferrin H & Minocycline; Minociclina [INN-Spanish]; Minocin (Hydrochloride); Minocin (TN); Minocyclinum [INN-Latin]; Vectrin (Hydrochloride); CRL-1605 & Minocycline; Minocycline (USAN/INN); Minocycline [USAN:BAN:INN]; (2Z,4S,4aS,5aR,12aS)-2-[amino(hydroxy)methylidene]-4,7-bis(dimethylamino)-10,11,12a-trihydroxy-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione; (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2-CARBOXAMIDE; 4,7-Bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-2-naphthacenecarboxamide; 7-Dimethylamino-6-demethyl-6-deoxytetracycline
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  Disease Class 1A00-1C4Z: Bacterial infection; ED90: Rosacea
  Therapeutic Class Antibiotics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C23H27N3O7
  InChI 1S/C23H27N3O7/c1-25(2)12-5-6-13(27)15-10(12)7-9-8-11-17(26(3)4)19(29)16(22(24)32)21(31)23(11,33)20(30)14(9)18(15)28/h5-6,9,11,17,27-28,31,33H,7-8H2,1-4H3,(H2,24,32)/t9-,11-,17-,23-/m0/s1
  InChIKey FFTVPQUHLQBXQZ-KVUCHLLUSA-N
  Canonical SMILES CN(C)C1C2CC3CC4=C(C=CC(=C4C(=C3C(=O)C2(C(=C(C1=O)C(=O)N)O)O)O)O)N(C)C
  External Link
Pubchem ID 54675783
CAS Number 10118-90-8
CHEBI ID 50694
TTD ID D08LTU

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM075  Increased risk of photosensitivity reactions
  Relation Graph
 Full list of drugs interacting with Minocycline (topical)
      Pharmacodynamic additive effects
   Increased risk of photosensitivity reactions Drug Num:  6
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0062
 
Aminolevulinic acid
 
C5H9NO3
 
137 
Major    Inter Info   
[1], [2]
D0063
 
Aminolevulinic acid (topical)
 
C5H9NO3
 
137 
Moderate    Inter Info   
[3], [4], [5]
D1028
 
Methoxsalen
 
C12H8O4
 
4114 
Moderate    Inter Info   
[3], [6], [7]
D1033
 
Methyl aminolevulinate (topical)
 
C6H11NO3
 
157922 
Moderate    Inter Info   
[3], [4], [5]
D1314
 
Porfimer sodium
 
C68H74N8O11
 
135577896 
Moderate    Inter Info   
[8], [4], [9]
D1691
 
Verteporfin
 
C82H84N8O16
 
11980904 
Moderate    Inter Info   
[4], [6], [10]
References
1 Product Information. Nulibry (fosdenopterin). Origin Biosciences Inc, Boston, MA.
2 Product Information. Gleolan (aminolevulinic acid). NX Development Corp, Lexington, KY.
3 Cerner Multum, Inc. "Australian Product Information.".
4 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
5 Product Information. Metvixia (methyl aminolevulinate topical). Galderma Laboratories Inc, Cranbury, NJ.
6 Multum Information Services, Inc. Expert Review Panel.
7 Product Information. Uvadex (methoxsalen). Therakos Inc, Exton, PA.
8 Blakely KM, Drucker AM, Rosen CF "Drug-induced photosensitivity-an update: Culprit drugs, prevention and management." Drug Saf 42 (2019): 827-47. [PMID: 30888626]
9 Product Information. Photofrin (porfimer). Sanofi Winthrop Pharmaceuticals, New York, NY.
10 Product Information. Visudyne (verteporfin) Valeant Pharmaceuticals, Costa Mesa, CA.