Details of Drug

Details of Drug

 Drug General Information (ID: D1058)
  Drug Name
Miconazole (topical)
  Drug Type Small molecule
  Drug Synonymous
Dactarin; MCZ; Miconazol; Miconazolo; Miconazolum; Micozole; Minostate; Monistat; Vusion; Zimycan; Daktarin IV; Miconasil Nitrate; Miconazole nitrate salt; Miconazolo [DCIT]; Monistat IV; MJR 1762; Miconazole 3; Miconazole 3 Combination Pack; Miconazole 7 Combination Pack; Monazole 7; Monistat 1 Combination Pack; Monistat 3 Vaginal Ovules; Monistat 5 Tampon; Monistat 7 Vaginal Suppositories; R 18134; Aflorix(nitrate); Albistat(nitrate); Andergin(nitrate); Conofite(nitrate); Daktarin (TN); Femizol (TN); Femizol-M; Florid(nitrate); Lotrimin AF(nitrate); Micantin (nitrate); Micatin (TN); Miconazex (TN); Miconazol [INN-Spanish]; Miconazole-7; Miconazolum [INN-Latin]; Monista (nitrate); Monistat (TN); Monistat 3 Dual-Pak; Monistat 7 Dual-Pak; Monistat Dual-PAK; Monistat iv (TN); Monistat-Derm; Novo-Miconazole Vaginal Ovules; Epi-Monistat(nitrate); Gyno-Daktar(nitrate); Monistat-Derm (TN); R-14,889; Miconazole (JP15/USP/INN); Miconazole [USAN:BAN:INN:JAN]; Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)-(9CI); Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)-(9CI); (+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole; 1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole; 1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole; 1-[2,4-Dichloro-beta-([2,4-dichloro-benzyl]oxy)phenethyl]imidazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; 1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole; 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole; 1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole; 1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
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  Disease Class 1F29-1F2F: Fungal infection
  Therapeutic Class Antifungal Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C18H14Cl4N2O
  InChI 1S/C18H14Cl4N2O/c19-13-2-1-12(16(21)7-13)10-25-18(9-24-6-5-23-11-24)15-4-3-14(20)8-17(15)22/h1-8,11,18H,9-10H2
  InChIKey BYBLEWFAAKGYCD-UHFFFAOYSA-N
  Canonical SMILES C1=CC(=C(C=C1Cl)Cl)COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl
  External Link
Pubchem ID 4189
CAS Number 22916-47-8
CHEBI ID 82892
TTD ID D00AXJ
INTEDE ID DR1084
VARIDT ID DR00477

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
BM017  CYP450 enzyme inhibition
  Relation Graph
 Full list of drugs interacting with Miconazole (topical)
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0481
 
Dicoumarol
 
C19H12O6
 
54676038 
Major    Inter Info   
[1], [2], [3]
D0087
 
Anisindione
 
C16H12O3
 
2197 
Major    Inter Info   
[1], [2], [3]
D1711
 
Warfarin
 
C19H16O4
 
54678486 
Major    Inter Info   
[1], [2], [3]
References
1 Colquhoun MC, Daly M, Stewart P, Beeley L "Interaction between warfarin and miconazole oral gel." Lancet 1 (1987): 695-6. [PMID: 2882124]
2 Shenfield GM, Page M "Potentiation of warfarin action by miconazole oral gel." Aust N Z J Med 21 (1991): 928. [PMID: 1818557]
3 Watson PG, Lochan RG, Redding VJ "Drug interaction with coumarin derivative anticoagulants." Br Med J 285 (1982): 1045-6. [PMID: 6812734]