Details of Drug

Details of Drug

 Drug General Information (ID: D1034)
  Drug Name
Methylcellulose
  Drug Type Small molecule
  Drug Synonymous
E461; methylated cellulose; CHEBI:53448; 4-O-[4-O-(2-O,3-O,4-O,6-O-Tetramethyl-beta-D-glucopyranosyl)-2-O,3-O,6-O-trimethyl-beta-D-glucopyranosyl]-1-O,2-O,3-O,6-O-tetramethyl-beta-D-glucopyranose
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  Therapeutic Class Laxatives
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C29H54O16
  InChI InChI=1S/C29H54O16/c1-30-12-15-18(33-4)21(34-5)25(38-9)28(42-15)45-20-17(14-32-3)43-29(26(39-10)23(20)36-7)44-19-16(13-31-2)41-27(40-11)24(37-8)22(19)35-6/h15-29H,12-14H2,1-11H3/t15-,16-,17-,18-,19-,20-,21+,22+,23+,24-,25-,26-,27-,28+,29+/m1/s1
  InChIKey LNAZSHAWQACDHT-XIYTZBAFSA-N
  Canonical SMILES COC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OC)OC)O[C@@H]3[C@H](O[C@H]([C@@H]([C@H]3OC)OC)OC)COC)COC)OC)OC)OC
  External Link
Pubchem ID 44263857

Drug-Drug Interaction Network
  Sunburst Graph
AM003  Affected organization distribution
AM006  Pharmacodynamic additive effects
BM014  Interference of cell/tissue uptake
BM064  Increased risk of hypoglycemia
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Methylcellulose
      Affected organization distribution
   Interference of cell/tissue uptake Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0670
 
Fludeoxyglucose (18F)
 
C6H11FO5
 
170049 
Moderate    Inter Info   
[1], [2], [3]
      Pharmacodynamic additive effects
   Increased risk of hypoglycemia Drug Num:  21
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0009
 
Acarbose
 
C25H43NO18
 
41774 
Minor    Inter Info   
[4], [5], [6]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Minor    Inter Info   
[4], [5], [6]
D0727
 
Glimepiride
 
C24H34N4O5S
 
3476 
Minor    Inter Info   
[4], [5], [6]
D0728
 
Glipizide
 
C21H27N5O4S
 
3478 
Minor    Inter Info   
[4], [5], [6]
D0730
 
Glyburide
 
C23H28ClN3O5S
 
3488 
Minor    Inter Info   
[4], [5], [6]
D0808
 
Insulin aspart (aspart)
 
C256H381N65O79S6
 
118984445 
Minor    Inter Info   
[4], [5], [6]
D0809
 
Insulin degludec
 
C274H411N65O81S6
 
118984462 
Minor    Inter Info   
[4], [5], [6]
D0810
 
Insulin detemir
 
C267H402N64O76S6
 
16137271 
Minor    Inter Info   
[4], [5], [6]
D0811
 
Insulin glargine
 
C267H404N72O78S6
 
118984454 
Minor    Inter Info   
[4], [5], [6]
D0812
 
Insulin glulisine
 
C258H384N64O78S6
 
16136701 
Minor    Inter Info   
[4], [5], [6]
D0814
 
Insulin human (inhalation, rapid acting)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0815
 
Insulin human (isophane)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0816
 
Insulin human (regular)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0817
 
Insulin human (zinc extended)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0818
 
Insulin human (zinc)
 
C257H383N65O77S6
 
118984375 
Minor    Inter Info   
[4], [5], [6]
D0819
 
Insulin lispro
 
C257H389N65O77S6
 
16132438 
Minor    Inter Info   
[4], [5], [6]
D1064
 
Miglitol
 
C8H17NO5
 
441314 
Minor    Inter Info   
[4], [5], [6]
D1112
 
Nateglinide
 
C19H27NO3
 
5311309 
Minor    Inter Info   
[4], [5], [6]
D1392
 
Repaglinide
 
C27H36N2O4
 
65981 
Minor    Inter Info   
[4], [5], [6]
D1601
 
Tolazamide
 
C14H21N3O3S
 
5503 
Minor    Inter Info   
[4], [5], [6]
D1603
 
Tolbutamide
 
C12H18N2O3S
 
5505 
Minor    Inter Info   
[4], [5], [6]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0929
 
Linaclotide
 
C59H79N15O21S6
 
16158208 
Minor    Inter Info   
[7], [8]
References
1 Cerner Multum, Inc. "Australian Product Information.".
2 Multum Information Services, Inc. Expert Review Panel.
3 Product Information. Metamucil (psyllium). Procter and Gamble Pharmaceutic, Cincinnati, OH.
4 Anderson JW, Allgood LD, Turner J, Oeltgen PR, Daggy BP "Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia." Am J Clin Nutr 70 (1999): 466-73. [PMID: 10500014]
5 Fugh-Berman A "Herb-drug interactions." Lancet 355 (2000): 134-8. [PMID: 10675182]
6 Jenkins DJ, Wolever TM, Leeds AR, et al "Dietary fibres, fibre analogues, and glucose tolerance: importance of viscosity." Br Med J 1 (1978): 1392-4. [PMID: 647304]
7 EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".
8 Product Information. Linzess (linaclotide). Forest Pharmaceuticals, St. Louis, MO.