Details of Drug

Drug General Information (ID: D1022)
Drug Name	Methionine
Drug Type	Small molecule
Drug Synonymous	Acimethin; Cymethion Click to Show/Hide
Therapeutic Class	Nutritional Supplements
Structure
Structure	3D Structure		2D Structure
Formula	C5H11NO2S
InChI	1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
InChIKey	FFEARJCKVFRZRR-BYPYZUCNSA-N
Canonical SMILES	CSCCC(C(=O)O)N
External Link
	Pubchem ID	6137
	CAS Number	63-68-3
	CHEBI ID	16643
	TTD ID	D0PO8E
	INTEDE ID	DR1043

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM001 Affected gastrointestinal absorption AM005 Affected excretion pathways BM004 Adsorption BM029 Altered urine pH
Relation Graph

Full list of drugs interacting with Methionine
Affected gastrointestinal absorption
	Adsorption					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0021		Activated charcoal	C	5462310	Moderate		Inter Info	[1]
Affected excretion pathways
	Altered urine pH					Drug Num: 4
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0579		Ephedrine	C10H15NO	9294	Minor		Inter Info	[2], [3], [4]
D0664		Flecainide	C17H20F6N2O3	3356	Minor		Inter Info	[5]
D1054		Mexiletine	C11H17NO	4178	Minor		Inter Info	[6]
D1363		Pseudoephedrine	C10H15NO	7028	Minor		Inter Info	[2], [3], [4]

References
1	Cerner Multum, Inc. "UK Summary of Product Characteristics.".
2	Brater DC, Kaojarern S, Benet LZ, et al "Renal excretion of pseudoephedrine." Clin Pharmacol Ther 28 (1980): 690-4. [PMID: 7438686]
3	Kuntzman RG, Tsai I, Brand L, Mark LC "The influence of urinary pH on the plasma half-life of pseudoephedrine in man and dog and a sensitive assay for its determination in human plasma." Clin Pharmacol Ther 12 (1971): 62-7. [PMID: 5541135]
4	Wilkinson GR, Beckett AH "Absorption metabolism and excretion of the ephedrines in man. I. The influence of urinary pH and urine volume output." J Pharmacol Exp Ther 162 (1968): 139-47. [PMID: 5656593]
5	Hertrampf R, Gundert-Remy U, Beckmann J, et al "Elimination of flecainide as a function of urinary flow rate and pH." Eur J Clin Pharmacol 41 (1991): 61-3. [PMID: 1782979]
6	Mitchell BG, Clements JA, Pottage A, Prescott LF "Mexiletine disposition: individual variation in response to urine acidification and alkalinisation." Br J Clin Pharmacol 16 (1983): 281-4. [PMID: 6626420]