Details of Drug

Drug General Information (ID: D0999)
Drug Name		Meningococcal polysaccharide vaccine group C
Drug Type		Vaccine
Drug Synonymous		DB13890; Meningococcal group C polysaccharide; Meningococcal group CCRM197 conjugate vaccine; Meningococcal polysaccharide antigen group C; Meningococcal polysaccharide vaccine group C; Neisseria meningitidis group C (strain C11) oligosaccharide CRM-197 adipic acid conjugate; Neisseria meningitidis group C capsular polysaccharide antigen Click to Show/Hide
Therapeutic Class		Vaccines

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM007 Pharmacodynamic antagonistic effects BM100 Antagonize the effect of vaccine/toxoid
Relation Graph

Full list of drugs interacting with Meningococcal polysaccharide vaccine group C
Pharmacodynamic antagonistic effects
	Antagonize the effect of vaccine/toxoid					Drug Num: 196
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0006		Abemaciclib	C27H32F2N8	46220502	Moderate		Inter Info	[1], [2], [3]
D0008		Acalabrutinib	C26H23N7O2	71226662	Moderate		Inter Info	[1], [2], [3]
D0023		Adalimumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0027		Aflibercept	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0030		Aldesleukin	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0032		Alefacept	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0033		Alemtuzumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0048		Altretamine	C9H18N6	2123	Moderate		Inter Info	[1], [2], [3]
D0085		Anakinra	C20H23N5O7S2	146171046	Moderate		Inter Info	[1], [2], [3]
D0091		Antilymphocyte immunoglobulin (horse)	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0094		Antithymocyte immunoglobulin (rabbit)	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0114		Asparaginase Escherichia coli	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0118		Atezolizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0134		Azacitidine	C8H12N4O5	9444	Moderate		Inter Info	[1], [2], [3]
D0136		Azathioprine	C9H7N7O2S	2265	Moderate		Inter Info	[1], [2], [3]
D0146		Baricitinib	C16H17N7O2S	44205240	Moderate		Inter Info	[1], [2], [3]
D0147		Basiliximab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0151		Belatacept	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0152		Belimumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0153		Belinostat	C15H14N2O4S	6918638	Moderate		Inter Info	[1], [2], [3]
D0157		Bendamustine	C16H21Cl2N3O2	65628	Moderate		Inter Info	[1], [2], [3]
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[1], [2], [3]
D0178		Bexarotene	C24H28O2	82146	Moderate		Inter Info	[1], [2], [3]
D0190		Bleomycin	C55H84N17O21S3+	5360373	Moderate		Inter Info	[1], [2], [3]
D0191		Blinatumomab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0193		Bortezomib	C19H25BN4O4	387447	Moderate		Inter Info	[1], [2], [3]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[1], [2], [3]
D0199		Brentuximab vedotin	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0204		Brigatinib	C29H39ClN7O2P	68165256	Moderate		Inter Info	[1], [2], [3]
D0209		Brodalumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0215		Budesonide	C25H34O6	5281004	Moderate		Inter Info	[1], [2], [3]
D0223		Busulfan	C6H14O6S2	2478	Moderate		Inter Info	[1], [2], [3]
D0227		Cabazitaxel	C45H57NO14	9854073	Moderate		Inter Info	[1], [2], [3]
D0246		Canakinumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0249		Capecitabine	C15H22FN3O6	60953	Moderate		Inter Info	[1], [2], [3]
D0260		Carboplatin	C6H12N2O4Pt	426756	Moderate		Inter Info	[1], [2], [3]
D0261		Carfilzomib	C40H57N5O7	11556711	Moderate		Inter Info	[1], [2], [3]
D0264		Carmustine	C5H9Cl2N3O2	2578	Moderate		Inter Info	[1], [2], [3]
D0304		Certolizumab pegol	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0312		Chlorambucil	C14H19Cl2NO2	2708	Moderate		Inter Info	[1], [2], [3]
D0344		Cisplatin	Cl2H6N2Pt	5702198	Moderate		Inter Info	[1], [2], [3]
D0348		Cladribine	C10H12ClN5O3	20279	Moderate		Inter Info	[1], [2], [3]
D0357		Clofarabine	C10H11ClFN5O3	119182	Moderate		Inter Info	[1], [2], [3]
D0376		Cobimetinib	C21H21F3IN3O2	16222096	Moderate		Inter Info	[1], [2], [3]
D0389		Copanlisib	C23H28N8O4	135565596	Moderate		Inter Info	[1], [2], [3]
D0392		Corticotropin	C207H308N56O58S	16132265	Moderate		Inter Info	[1], [2], [3]
D0400		Cyclophosphamide	C7H15Cl2N2O2P	2907	Moderate		Inter Info	[1], [2], [3]
D0402		Cyclosporine	C62H111N11O12	5284373	Moderate		Inter Info	[1], [2], [3]
D0404		Cytarabine	C9H13N3O5	6253	Moderate		Inter Info	[1], [2], [3]
D0407		Dacarbazine	C6H10N6O	135398738	Moderate		Inter Info	[1], [2], [3]
D0410		Dactinomycin	C62H86N12O16	457193	Moderate		Inter Info	[1], [2], [3]
D0422		Daratumumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[1], [2], [3]
D0429		Daunorubicin	C27H29NO10	30323	Moderate		Inter Info	[1], [2], [3]
D0430		Daunorubicin (liposomal)	C27H29NO10	30323	Moderate		Inter Info	[1], [2], [3]
D0431		Decitabine	C8H12N4O4	451668	Moderate		Inter Info	[1], [2], [3]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[1], [2], [3]
D0442		Denileukin diftitox	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[1], [2], [3]
D0499		Dimethyl fumarate	C6H8O4	637568	Moderate		Inter Info	[1], [2], [3]
D0501		Dinutuximab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0511		Docetaxel	C43H53NO14	148124	Moderate		Inter Info	[1], [2], [3]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[1], [2], [3]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Moderate		Inter Info	[1], [2], [3]
D0541		Durvalumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0543		Duvelisib	C22H17ClN6O	50905713	Moderate		Inter Info	[1], [2], [3]
D0553		Efalizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0560		Elotuzumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0571		Enfortumab vedotin	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0584		Epirubicin	C27H29NO11	41867	Moderate		Inter Info	[1], [2], [3]
D0594		Eribulin	C40H59NO11	11354606	Moderate		Inter Info	[1], [2], [3]
D0614		Etanercept	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0627		Etoposide	C29H32O13	36462	Moderate		Inter Info	[1], [2], [3]
D0629		Everolimus	C53H83NO14	6442177	Moderate		Inter Info	[1], [2], [3]
D0666		Floxuridine	C9H11FN2O5	5790	Moderate		Inter Info	[1], [2], [3]
D0669		Fludarabine	C10H12FN5O4	657237	Moderate		Inter Info	[1], [2], [3]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[1], [2], [3]
D0675		Fluorouracil	C4H3FN2O2	3385	Moderate		Inter Info	[1], [2], [3]
D0714		Gemcitabine	C9H11F2N3O4	60750	Moderate		Inter Info	[1], [2], [3]
D0717		Gemtuzumab ozogamicin	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0736		Golimumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0747		Guselkumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[1], [2], [3]
D0784		Ibritumomab tiuxetan	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0785		Ibrutinib	C25H24N6O2	24821094	Moderate		Inter Info	[1], [2], [3]
D0788		Idarubicin	C26H27NO9	42890	Moderate		Inter Info	[1], [2], [3]
D0789		Idelalisib	C22H18FN7O	11625818	Moderate		Inter Info	[1], [2], [3]
D0790		Ifosfamide	C7H15Cl2N2O2P	3690	Moderate		Inter Info	[1], [2], [3]
D0793		Imatinib	C29H31N7O	5291	Moderate		Inter Info	[1], [2], [3]
D0801		Inebilizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0802		Infliximab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0806		Inotuzumab ozogamicin	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0829		Iobenguane (I-131)	C8H10IN3	60860	Moderate		Inter Info	[1], [2], [3]
D0845		Irinotecan	C33H38N4O6	60838	Moderate		Inter Info	[1], [2], [3]
D0846		Irinotecan (liposomal)	C33H38N4O6	60838	Moderate		Inter Info	[1], [2], [3]
D0873		Ixabepilone	C27H42N2O5S	6445540	Moderate		Inter Info	[1], [2], [3]
D0874		Ixazomib	C14H19BCl2N2O4	25183872	Moderate		Inter Info	[1], [2], [3]
D0875		Ixekizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0900		Leflunomide	C12H9F3N2O2	3899	Moderate		Inter Info	[1], [2], [3]
D0902		Lenalidomide	C13H13N3O3	216326	Moderate		Inter Info	[1], [2], [3]
D0910		Levamisole	C11H12N2S	26879	Moderate		Inter Info	[1], [2], [3]
D0945		Lomustine	C9H16ClN3O2	3950	Moderate		Inter Info	[1], [2], [3]
D0962		Lurbinectedin	C41H44N4O10S	57327016	Moderate		Inter Info	[1], [2], [3]
D0986		Mechlorethamine	C5H11Cl2N	4033	Moderate		Inter Info	[1], [2], [3]
D0996		Melphalan	C13H18Cl2N2O2	460612	Moderate		Inter Info	[1], [2], [3]
D0129		Avapritinib	C26H27FN10	118023034	Moderate		Inter Info	[1], [2], [3]
D0132		Axicabtagene ciloleucel	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0150		Belantamab mafodotin	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0203		Brexucabtagene autoleucel	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0507		Diroximel fumarate	C11H13NO6	73330464	Moderate		Inter Info	[1], [2], [3]
D0851		Isatuximab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0939		Lisocabtagene maraleucel	NA	NA	Moderate		Inter Info	[1], [2], [3]
D0964		Lutetium Lu 177 dotatate	C65H87LuN14O19S2	76966897	Moderate		Inter Info	[1], [2], [3]
D1085		Monomethyl fumarate	C5H6O4	5369209	Moderate		Inter Info	[1], [2], [3]
D1113		Naxitamab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1410		Risankizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1448		Satralizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1529		Tafasitamab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1583		Tildrakizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1622		Trastuzumab deruxtecan	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1666		Upadacitinib	C17H19F3N6O	58557659	Moderate		Inter Info	[1], [2], [3]
D1718		Zanubrutinib	C27H29N5O3	135565884	Moderate		Inter Info	[1], [2], [3]
D1007		Mercaptopurine	C5H4N4S	667490	Moderate		Inter Info	[1], [2], [3]
D1025		Methotrexate	C20H22N8O5	126941	Moderate		Inter Info	[1], [2], [3]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[1], [2], [3]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[1], [2], [3]
D1077		Mitomycin	C15H18N4O5	5746	Moderate		Inter Info	[1], [2], [3]
D1079		Mitoxantrone	C22H28N4O6	4212	Moderate		Inter Info	[1], [2], [3]
D1093		Muromonab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1094		Mycophenolate mofetil	C23H31NO7	5281078	Moderate		Inter Info	[1], [2], [3]
D1095		Mycophenolic acid	C17H20O6	446541	Moderate		Inter Info	[1], [2], [3]
D1111		Natalizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1118		Nelarabine	C11H15N5O5	3011155	Moderate		Inter Info	[1], [2], [3]
D1136		Nilotinib	C28H22F3N7O	644241	Moderate		Inter Info	[1], [2], [3]
D1140		Niraparib	C19H20N4O	24958200	Moderate		Inter Info	[1], [2], [3]
D1161		Obinutuzumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1164		Ofatumumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1167		Olaparib	C24H23FN4O3	23725625	Moderate		Inter Info	[1], [2], [3]
D1168		Olaratumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1174		Omacetaxine mepesuccinate	C29H39NO9	285033	Moderate		Inter Info	[1], [2], [3]
D1190		Osimertinib	C28H33N7O2	71496458	Moderate		Inter Info	[1], [2], [3]
D1193		Oxaliplatin	C8H14N2O4Pt	9887053	Moderate		Inter Info	[1], [2], [3]
D1212		Paclitaxel	C47H51NO14	36314	Moderate		Inter Info	[1], [2], [3]
D1213		Paclitaxel (protein-bound)	C47H51NO14	36314	Moderate		Inter Info	[1], [2], [3]
D1214		Palbociclib	C24H29N7O2	5330286	Moderate		Inter Info	[1], [2], [3]
D1221		Panobinostat	C21H23N3O2	6918837	Moderate		Inter Info	[1], [2], [3]
D1232		Pazopanib	C21H23N7O2S	10113978	Moderate		Inter Info	[1], [2], [3]
D1241		Pemetrexed	C20H21N5O6	135410875	Moderate		Inter Info	[1], [2], [3]
D1250		Pentostatin	C11H16N4O4	439693	Moderate		Inter Info	[1], [2], [3]
D1305		Plicamycin	C52H76O24	163659	Moderate		Inter Info	[1], [2], [3]
D1306		Polatuzumab vedotin	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1312		Pomalidomide	C13H11N3O4	134780	Moderate		Inter Info	[1], [2], [3]
D1313		Ponatinib	C29H27F3N6O	24826799	Moderate		Inter Info	[1], [2], [3]
D1323		Pralatrexate	C23H23N7O5	148121	Moderate		Inter Info	[1], [2], [3]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[1], [2], [3]
D1345		Procarbazine	C12H19N3O	4915	Moderate		Inter Info	[1], [2], [3]
D1398		Ribociclib	C23H30N8O	44631912	Moderate		Inter Info	[1], [2], [3]
D1403		Rilonacept	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1416		Rituximab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1424		Romidepsin	C24H36N4O6S2	5352062	Moderate		Inter Info	[1], [2], [3]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[1], [2], [3]
D1434		Ruxolitinib	C17H18N6	25126798	Moderate		Inter Info	[1], [2], [3]
D1447		Sarilumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1454		Secukinumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1458		Selinexor	C17H11F6N7O	71481097	Moderate		Inter Info	[1], [2], [3]
D1467		Siltuximab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1476		Sirolimus	C51H79NO13	5284616	Moderate		Inter Info	[1], [2], [3]
D1508		Streptozocin	C8H15N3O7	29327	Moderate		Inter Info	[1], [2], [3]
D1526		Tacrolimus	C44H69NO12	445643	Moderate		Inter Info	[1], [2], [3]
D1532		Talazoparib	C19H14F2N6O	135565082	Moderate		Inter Info	[1], [2], [3]
D1548		Temozolomide	C6H6N6O2	5394	Moderate		Inter Info	[1], [2], [3]
D1549		Temsirolimus	C56H87NO16	6918289	Moderate		Inter Info	[1], [2], [3]
D1551		Teniposide	C32H32O13S	452548	Moderate		Inter Info	[1], [2], [3]
D1563		Tetracosactide	C136H210N40O31S	16133802	Moderate		Inter Info	[1], [2], [3]
D1569		Thalidomide	C13H10N2O4	5426	Moderate		Inter Info	[1], [2], [3]
D1575		Thiotepa	C6H12N3PS	5453	Moderate		Inter Info	[1], [2], [3]
D1589		Tioguanine	C5H5N5S	2723601	Moderate		Inter Info	[1], [2], [3]
D1594		Tisagenlecleucel	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1599		Tocilizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1600		Tofacitinib	C16H20N6O	9926791	Moderate		Inter Info	[1], [2], [3]
D1610		Topotecan	C23H23N3O5	60700	Moderate		Inter Info	[1], [2], [3]
D1613		Tositumomab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1614		Tositumomab (I-131)	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1615		Trabectedin	C39H43N3O11S	108150	Moderate		Inter Info	[1], [2], [3]
D1621		Trastuzumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[1], [2], [3]
D1630		Triamcinolone (ophthalmic)	C21H27FO6	31307	Moderate		Inter Info	[1], [2], [3]
D1639		Trifluridine	C10H11F3N2O5	6256	Moderate		Inter Info	[1], [2], [3]
D1667		Uracil mustard	C8H11Cl2N3O2	6194	Moderate		Inter Info	[1], [2], [3]
D1671		Ustekinumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1685		Vedolizumab	NA	NA	Moderate		Inter Info	[1], [2], [3]
D1688		Venetoclax	C45H50ClN7O7S	49846579	Moderate		Inter Info	[1], [2], [3]
D1697		Vinblastine	C46H58N4O9	13342	Moderate		Inter Info	[1], [2], [3]
D1698		Vincristine	C46H56N4O10	5978	Moderate		Inter Info	[1], [2], [3]
D1699		Vincristine (liposome)	C46H56N4O10	5978	Moderate		Inter Info	[1], [2], [3]
D1700		Vinorelbine	C45H54N4O8	5311497	Moderate		Inter Info	[1], [2], [3]

References
1	CDC. Centers for Disease Control and Prevention/ "Recommendations of the advisory committtee on immunization practices (ACIP): use of vaccines and immune globulins in persons with altered immunocompetence." MMWR Morb Mortal Wkly Rep 42(RR-04) (1993): 1-18. [PMID: 20300058]
2	Product Information. Imovax Rabies (rabies vaccine). sanofi pasteur, Swiftwater, PA.
3	Department of Health. National Health Service "Immunisation Against Infectious Disease - "The Green Book". Chapter 6: Contraindications and special considerations.".

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