Details of Drug

Details of Drug

 Drug General Information (ID: D0939)
  Drug Name
Lisocabtagene maraleucel
  Drug Type Autologous cell transplant
  Drug Synonymous
JCAR017
    Click to Show/Hide
  Disease Class 2B33: Malignant haematopoietic neoplasm; 2A70: Precursor B-lymphoblastic neoplasm; 2A80: Follicular lymphoma; 2A81: Diffuse large B-cell lymphoma
  Therapeutic Class Antineoplastics
  External Link
TTD ID D0M4WU

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM043  Additive immunosuppressive effects
BM044  Additive myelosuppressive effects
BM100  Antagonize the effect of vaccine/toxoid
BM105  Antagonize the effect of probiotics
BM106  Diminish the response to diagnostic skin test antigens
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Lisocabtagene maraleucel
      Pharmacodynamic additive effects
   Additive immunosuppressive effects Drug Num:  21
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0614
 
Etanercept
 
NA
 
NA
Major    Inter Info   
[1], [2], [3], [4], [5], [6]
D0661
 
Fingolimod
 
C19H33NO2
 
107970 
Major    Inter Info   
[7]
D0736
 
Golimumab
 
NA
 
NA
Major    Inter Info   
[1], [2], [3], [4], [5], [6]
D0802
 
Infliximab
 
NA
 
NA
Major    Inter Info   
[1], [2], [3], [4], [5], [6]
D0900
 
Leflunomide
 
C12H9F3N2O2
 
3899 
Major    Inter Info   
[8], [9]
D1111
 
Natalizumab
 
NA
 
NA
Major    Inter Info   
[13]
D1211
 
Ozanimod
 
C23H24N4O3
 
52938427 
Major    Inter Info   
[14], [15]
D1474
 
Siponimod
 
C29H35F3N2O3
 
44599207 
Major    Inter Info   
[17], [18]
D1556
 
Teriflunomide
 
C12H9F3N2O2
 
54684141 
Major    Inter Info   
[8], [9]
D1600
 
Tofacitinib
 
C16H20N6O
 
9926791 
Major    Inter Info   
[22]
D1666
 
Upadacitinib
 
C17H19F3N6O
 
58557659 
Major    Inter Info   
[23]
D1140
 
Niraparib
 
C19H20N4O
 
24958200 
Moderate    Inter Info   
[34]
D1162
 
Ocrelizumab
 
NA
 
NA
Moderate    Inter Info   
[35]
D1167
 
Olaparib
 
C24H23FN4O3
 
23725625 
Moderate    Inter Info   
[14], [36]
D1174
 
Omacetaxine mepesuccinate
 
C29H39NO9
 
285033 
Moderate    Inter Info   
[37]
D1403
 
Rilonacept
 
NA
 
NA
Moderate    Inter Info   
[40], [41], [42]
D1422
 
Roflumilast
 
C17H14Cl2F2N2O3
 
449193 
Moderate    Inter Info   
[14], [43]
D1509
 
Strontium chloride Sr-89
 
Cl2Sr
 
5388879 
Moderate    Inter Info   
[17], [14], [44]
D1610
 
Topotecan
 
C23H23N3O5
 
60700 
Moderate    Inter Info   
[45]
D1671
 
Ustekinumab
 
NA
 
NA
Moderate    Inter Info   
[49]
D1720
 
Zidovudine
 
C10H13N5O4
 
35370 
Moderate    Inter Info   
[17], [14], [50]
   Additive myelosuppressive effects Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1443
 
Samarium (153Sm) lexidronam
 
Sm
 
23951 
Major    Inter Info   
[16]
D0710
 
Ganciclovir
 
C9H13N5O4
 
135398740 
Moderate    Inter Info   
[17], [14], [29], [30]
D1676
 
Valganciclovir
 
C14H22N6O5
 
135413535 
Moderate    Inter Info   
[17], [14], [29], [30]
      Pharmacodynamic antagonistic effects
   Antagonize the effect of vaccine/toxoid Drug Num:  15
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1839
 
Measles virus vaccine live attenuated
 
NA
 
NA
Major    Inter Info   
[10], [11], [12]
D1881
 
Rotavirus vaccine
 
NA
 
NA
Major    Inter Info   
[10], [11], [12]
D1890
 
Smallpox (Vaccinia) Vaccine, Live
 
NA
 
NA
Major    Inter Info   
[19], [17], [20]
D1897
 
Talimogene laherparepvec
 
NA
 
NA
Major    Inter Info   
[21]
D1914
 
Typhoid vaccine (live)
 
NA
 
NA
Major    Inter Info   
[10], [11], [12]
D1920
 
Varicella Zoster Vaccine (Recombinant)
 
NA
 
NA
Major    Inter Info   
[10], [11], [12]
D1922
 
Yellow Fever Vaccine
 
NA
 
NA
Major    Inter Info   
[10], [11], [12]
D0366
 
Clostridium tetani toxoid antigen (formaldehyde inactivated)
 
NA
 
NA
Moderate    Inter Info   
[19], [24], [25]
D0755
 
Hepatitis A Vaccine
 
NA
 
NA
Moderate    Inter Info   
[19], [24], [25]
D0756
 
Hepatitis B Vaccine (Recombinant)
 
NA
 
NA
Moderate    Inter Info   
[19], [24], [25]
D0767
 
Human papillomavirus type 11 L1 capsid protein antigen
 
NA
 
NA
Moderate    Inter Info   
[19], [24], [25]
D0803
 
Influenza A virus A/California/7/2009 (H1N1)-like antigen (propiolactone inactivated)
 
NA
 
NA
Moderate    Inter Info   
[19], [24], [25]
D0804
 
Influenza A virus A/Vietnam/1194/2004 (H5N1) antigen (formaldehyde inactivated)
 
NA
 
NA
Moderate    Inter Info   
[19], [24], [25]
D0999
 
Meningococcal polysaccharide vaccine group C
 
NA
 
NA
Moderate    Inter Info   
[19], [24], [25]
D1307
 
Poliovirus type 1 antigen (formaldehyde inactivated)
 
NA
 
NA
Moderate    Inter Info   
[19], [24], [25]
   Antagonize the effect of probiotics Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1827
 
Lactobacillus acidophilus
 
NA
 
NA
Moderate    Inter Info   
[31], [32], [33]
   Diminish the response to diagnostic skin test antigens Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1912
 
Trichophyton mentagrophytes
 
NA
 
NA
Moderate    Inter Info   
[46], [47], [48]
D1913
 
Tuberculin purified protein derivative
 
NA
 
NA
Moderate    Inter Info   
[46], [47], [48]
   Attenuated pharmacological effects (Unspecific) Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0659
 
Filgrastim
 
NA
 
NA
Moderate    Inter Info   
[26], [27], [28]
D1235
 
Pegfilgrastim
 
C27H46N4O19
 
70683024 
Moderate    Inter Info   
[38], [39]
D1446
 
Sargramostim
 
NA
 
NA
Moderate    Inter Info   
[26], [27], [28]
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16 Product Information. Quadramet (samarium sm 153 lexidronam) Berlex Laboratories, Richmond, CA.
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50 Product Information. Retrovir (zidovudine). Glaxo Wellcome, Research Triangle Park, NC.