Details of Drug

Details of Drug

 Drug General Information (ID: D0871)
  Drug Name
Ivermectin (topical)
  Drug Type Small molecule
  Drug Synonymous
I 8898; Ivexterm (TN); MK-933; Mectizan (TN); Stromectol (TN)
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  Disease Class 1F6B: Strongyloidiasis
  Therapeutic Class Antiprotozoal Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C48H74O14
  InChI 1S/C48H74O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25-,26-,28-,30-,31-,33+,34-,35-,36-,37-,38-,39-,40+,41-,42-,43+,44-,45+,47+,48+/m0/s1
  InChIKey AZSNMRSAGSSBNP-XPNPUAGNSA-N
  Canonical SMILES CCC(C)C1C(CCC2(O1)CC3CC(O2)CC=C(C(C(C=CC=C4COC5C4(C(C=C(C5O)C)C(=O)O3)O)C)OC6CC(C(C(O6)C)OC7CC(C(C(O7)C)O)OC)OC)C)C
  External Link
Pubchem ID 6321424
CAS Number 71827-03-7
CHEBI ID 63941
TTD ID D09YHJ
INTEDE ID DR0899
VARIDT ID DR00147

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
BM017  CYP450 enzyme inhibition
BM022  CYP450 enzyme induction
  Relation Graph
 Full list of drugs interacting with Ivermectin (topical)
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme induction Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0545
 
Echinacea
 
NA
 
NA
Moderate    Inter Info   
[1], [2]
References
1 Cerner Multum, Inc. "Australian Product Information.".
2 Gorski JC, Huang SM, Pinto A, et al. "The effect of echinacea (Echinacea purpurea root) on cytochrome P450 activity in vivo." Clin Pharmacol Ther 75 (2004): 89-100. [PMID: 14749695]