Drug General Information (ID: D0784)
  Drug Name
Ibritumomab tiuxetan
  Drug Type Monoclonal antibody
  Drug Synonymous
2-[[2-[bis(carboxymethyl)amino]-3-[4-(methylcarbamoylamino)phenyl]propyl]-[2-[bis(carboxymethyl)amino]propyl]amino]acetic acid; 206181-63-7; Ibritumomab; Ibritumomab tiuxetan; Zevalin
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  Therapeutic Class Antineoplastics

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM043  Additive immunosuppressive effects
BM044  Additive myelosuppressive effects
BM050  Increased risk of bleeding
BM100  Antagonize the effect of vaccine/toxoid
BM105  Antagonize the effect of probiotics
BM106  Diminish the response to diagnostic skin test antigens
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Ibritumomab tiuxetan
      Pharmacodynamic additive effects
   Additive immunosuppressive effects Drug Num:  39
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0023
 
Adalimumab
 
NA
 
NA
Major    Inter Info   
[2], [3], [4]
D0614
 
Etanercept
 
NA
 
NA
Major    Inter Info   
[2], [3], [4]
D0146
 
Baricitinib
 
C16H17N7O2S
 
44205240 
Major    Inter Info   
[12], [7], [13]
D0304
 
Certolizumab pegol
 
NA
 
NA
Major    Inter Info   
[2], [3], [4]
D0348
 
Cladribine
 
C10H12ClN5O3
 
20279 
Major    Inter Info   
[7], [16]
D0661
 
Fingolimod
 
C19H33NO2
 
107970 
Major    Inter Info   
[22]
D0736
 
Golimumab
 
NA
 
NA
Major    Inter Info   
[2], [3], [4]
D0900
 
Leflunomide
 
C12H9F3N2O2
 
3899 
Major    Inter Info   
[26], [27]
D1111
 
Natalizumab
 
NA
 
NA
Major    Inter Info   
[28]
D1211
 
Ozanimod
 
C23H24N4O3
 
52938427 
Major    Inter Info   
[7], [30]
D1474
 
Siponimod
 
C29H35F3N2O3
 
44599207 
Major    Inter Info   
[12], [36]
D1556
 
Teriflunomide
 
C12H9F3N2O2
 
54684141 
Major    Inter Info   
[26], [27]
D1600
 
Tofacitinib
 
C16H20N6O
 
9926791 
Major    Inter Info   
[42]
D1666
 
Upadacitinib
 
C17H19F3N6O
 
58557659 
Major    Inter Info   
[45]
D0802
 
Infliximab
 
NA
 
NA
Major    Inter Info   
[2], [3], [4]
D0085
 
Anakinra
 
C20H23N5O7S2
 
146171046 
Moderate    Inter Info   
[46], [47], [48]
D0032
 
Alefacept
 
NA
 
NA
Moderate    Inter Info   
[37], [49], [50]
D0033
 
Alemtuzumab
 
NA
 
NA
Moderate    Inter Info   
[51], [50]
D0136
 
Azathioprine
 
C9H7N7O2S
 
2265 
Moderate    Inter Info   
[12], [7], [50]
D0246
 
Canakinumab
 
NA
 
NA
Moderate    Inter Info   
[46], [47], [48]
D0313
 
Chloramphenicol
 
C11H12Cl2N2O5
 
5959 
Moderate    Inter Info   
[12], [7], [63]
D0314
 
Chloramphenicol (ophthalmic)
 
C11H12Cl2N2O5
 
5959 
Moderate    Inter Info   
[12], [7], [63]
D0443
 
Denosumab
 
NA
 
NA
Moderate    Inter Info   
[50], [67]
D0499
 
Dimethyl fumarate
 
C6H8O4
 
637568 
Moderate    Inter Info   
[69]
D0507
 
Diroximel fumarate
 
C11H13NO6
 
73330464 
Moderate    Inter Info   
[69]
D0553
 
Efalizumab
 
NA
 
NA
Moderate    Inter Info   
[70]
D1085
 
Monomethyl fumarate
 
C5H6O4
 
5369209 
Moderate    Inter Info   
[69]
D1140
 
Niraparib
 
C19H20N4O
 
24958200 
Moderate    Inter Info   
[74]
D1162
 
Ocrelizumab
 
NA
 
NA
Moderate    Inter Info   
[75]
D1167
 
Olaparib
 
C24H23FN4O3
 
23725625 
Moderate    Inter Info   
[7], [76]
D1375
 
Radium Ra 223 dichloride
 
NA
 
NA
Moderate    Inter Info   
[78]
D1403
 
Rilonacept
 
NA
 
NA
Moderate    Inter Info   
[46], [47], [48]
D1422
 
Roflumilast
 
C17H14Cl2F2N2O3
 
449193 
Moderate    Inter Info   
[7], [79]
D1487
 
Sodium phosphate, monobasic (p32)
 
NA
 
NA
Moderate    Inter Info   
[80]
D1509
 
Strontium chloride Sr-89
 
Cl2Sr
 
5388879 
Moderate    Inter Info   
[12], [7], [81]
D1610
 
Topotecan
 
C23H23N3O5
 
60700 
Moderate    Inter Info   
[83]
D1671
 
Ustekinumab
 
NA
 
NA
Moderate    Inter Info   
[84]
D1720
 
Zidovudine
 
C10H13N5O4
 
35370 
Moderate    Inter Info   
[12], [7], [85]
D1855
 
Palifermin
 
NA
 
NA
Moderate    Inter Info   
[87]
   Additive myelosuppressive effects Drug Num:  5
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0370
 
Clozapine
 
C18H19ClN4
 
135398737 
Major    Inter Info   
[7], [17], [18]
D0433
 
Deferiprone
 
C7H9NO2
 
2972 
Major    Inter Info   
[12], [20], [21]
D1443
 
Samarium (153Sm) lexidronam
 
Sm
 
23951 
Major    Inter Info   
[35]
D0710
 
Ganciclovir
 
C9H13N5O4
 
135398740 
Moderate    Inter Info   
[12], [7], [71]
D1676
 
Valganciclovir
 
C14H22N6O5
 
135413535 
Moderate    Inter Info   
[12], [7], [71]
   Increased risk of bleeding Drug Num:  114
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0005
 
Abciximab
 
NA
 
NA
Major    Inter Info   
[1]
D0047
 
Alteplase
 
NA
 
NA
Major    Inter Info   
[1]
D0088
 
Anistreplase
 
NA
 
NA
Major    Inter Info   
[1]
D0189
 
Bivalirudin
 
C98H138N24O33
 
16129704 
Major    Inter Info   
[1]
D0537
 
Drotrecogin alfa
 
NA
 
NA
Major    Inter Info   
[1]
D0588
 
Eptifibatide
 
C35H49N11O9S2
 
448812 
Major    Inter Info   
[1]
D0008
 
Acalabrutinib
 
C26H23N7O2
 
71226662 
Major    Inter Info   
[5], [6]
D0017
 
Acetylsalicylic acid
 
C9H8O4
 
2244 
Major    Inter Info   
[1]
D0084
 
Anagrelide
 
C10H7Cl2N3O
 
135409400 
Major    Inter Info   
[1]
D0087
 
Anisindione
 
C16H12O3
 
2197 
Major    Inter Info   
[1]
D0092
 
Antithrombin Alfa
 
NA
 
NA
Major    Inter Info   
[1]
D0093
 
Antithrombin III human
 
NA
 
NA
Major    Inter Info   
[1]
D0096
 
Apixaban
 
C25H25N5O4
 
10182969 
Major    Inter Info   
[1]
D0102
 
Ardeparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[1]
D0104
 
Argatroban
 
C23H36N6O5S
 
92722 
Major    Inter Info   
[1]
D0129
 
Avapritinib
 
C26H27FN10
 
118023034 
Major    Inter Info   
[7], [8]
D0176
 
Betrixaban
 
C23H22ClN5O3
 
10275777 
Major    Inter Info   
[1]
D0182
 
Binimetinib
 
C17H15BrF2N4O3
 
10288191 
Major    Inter Info   
[1]
D0210
 
Bromfenac
 
C15H12BrNO3
 
60726 
Major    Inter Info   
[1]
D0230
 
Cabozantinib
 
C28H24FN3O5
 
25102847 
Major    Inter Info   
[14], [15]
D0247
 
Cangrelor
 
C17H25Cl2F3N5O12P3S2
 
9854012 
Major    Inter Info   
[1]
D0250
 
Caplacizumab
 
NA
 
NA
Major    Inter Info   
[1]
D0336
 
Cilostazol
 
C20H27N5O2
 
2754 
Major    Inter Info   
[1]
D0364
 
Clopidogrel
 
C16H16ClNO2S
 
60606 
Major    Inter Info   
[1]
D0414
 
Dalteparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[1]
D0415
 
Danaparoid
 
NA
 
NA
Major    Inter Info   
[1]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Major    Inter Info   
[1]
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Major    Inter Info   
[5], [19]
D0435
 
Defibrotide
 
C20H21N4O6P
 
135565962 
Major    Inter Info   
[1]
D0476
 
Diclofenac
 
C14H11Cl2NO2
 
3033 
Major    Inter Info   
[1]
D0481
 
Dicoumarol
 
C19H12O6
 
54676038 
Major    Inter Info   
[1]
D0489
 
Diflunisal
 
C13H8F2O3
 
3059 
Major    Inter Info   
[1]
D0506
 
Dipyridamole
 
C24H40N8O4
 
3108 
Major    Inter Info   
[1]
D0551
 
Edoxaban
 
C24H30ClN7O4S
 
10280735 
Major    Inter Info   
[1]
D0569
 
Encorafenib
 
C22H27ClFN7O4S
 
50922675 
Major    Inter Info   
[1]
D0574
 
Enoxaparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[1]
D0586
 
Epoprostenol
 
C20H32O5
 
5282411 
Major    Inter Info   
[1]
D0624
 
Etodolac
 
C17H21NO3
 
3308 
Major    Inter Info   
[1]
D0638
 
Fedratinib
 
C27H36N6O3S
 
16722836 
Major    Inter Info   
[1]
D0645
 
Fenoprofen
 
C15H14O3
 
3342 
Major    Inter Info   
[1]
D0680
 
Flurbiprofen
 
C15H13FO2
 
3394 
Major    Inter Info   
[1]
D0690
 
Fondaparinux
 
C31H53N3O49S8
 
5282448 
Major    Inter Info   
[1]
D0753
 
Heparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[1]
D0785
 
Ibrutinib
 
C25H24N6O2
 
24821094 
Major    Inter Info   
[23], [24], [7]
D0786
 
Ibuprofen
 
C13H18O2
 
3672 
Major    Inter Info   
[1]
D0792
 
Iloprost
 
C22H32O4
 
5311181 
Major    Inter Info   
[1]
D0800
 
Indomethacin
 
C19H16ClNO4
 
3715 
Major    Inter Info   
[1]
D0805
 
Inotersen
 
C230H318N69O121P19S19
 
121492004 
Major    Inter Info   
[7], [5], [25]
D0881
 
Ketoprofen
 
C16H14O3
 
3825 
Major    Inter Info   
[1]
D0882
 
Ketorolac
 
C15H13NO3
 
3826 
Major    Inter Info   
[1]
D0988
 
Meclofenamic acid
 
C14H11Cl2NO2
 
4037 
Major    Inter Info   
[1]
D0991
 
Mefenamic acid
 
C15H15NO2
 
4044 
Major    Inter Info   
[1]
D0995
 
Meloxicam
 
C14H13N3O4S2
 
54677470 
Major    Inter Info   
[1]
D1097
 
Nabumetone
 
C15H16O2
 
4409 
Major    Inter Info   
[1]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Major    Inter Info   
[1]
D1174
 
Omacetaxine mepesuccinate
 
C29H39NO9
 
285033 
Major    Inter Info   
[5], [29]
D1196
 
Oxaprozin
 
C18H15NO3
 
4614 
Major    Inter Info   
[1]
D1274
 
Phenylbutazone
 
C19H20N2O2
 
4781 
Major    Inter Info   
[1]
D1300
 
Piroxicam
 
C15H13N3O4S
 
54676228 
Major    Inter Info   
[1]
D1305
 
Plicamycin
 
C52H76O24
 
163659 
Major    Inter Info   
[1]
D1313
 
Ponatinib
 
C29H27F3N6O
 
24826799 
Major    Inter Info   
[5], [31]
D1328
 
Prasugrel
 
C20H20FNO3S
 
6918456 
Major    Inter Info   
[1]
D1380
 
Ramucirumab
 
NA
 
NA
Major    Inter Info   
[5], [32]
D1387
 
Regorafenib
 
C21H15ClF4N4O3
 
11167602 
Major    Inter Info   
[7], [33], [34]
D1417
 
Rivaroxaban
 
C19H18ClN3O5S
 
9875401 
Major    Inter Info   
[1]
D1434
 
Ruxolitinib
 
C17H18N6
 
25126798 
Major    Inter Info   
[1]
D1506
 
Streptokinase
 
C11H19NO2
 
9815560 
Major    Inter Info   
[1]
D1518
 
Sulfinpyrazone
 
C23H20N2O3S
 
5342 
Major    Inter Info   
[1]
D1520
 
Sulindac
 
C20H17FO3S
 
1548887 
Major    Inter Info   
[1]
D1581
 
Ticlopidine
 
C14H14ClNS
 
5472 
Major    Inter Info   
[1]
D1588
 
Tinzaparin
 
C26H42N2O37S5
 
772 
Major    Inter Info   
[1]
D1592
 
Tipranavir
 
C31H33F3N2O5S
 
54682461 
Major    Inter Info   
[40], [41], [5]
D1593
 
Tirofiban
 
C22H36N2O5S
 
60947 
Major    Inter Info   
[1]
D1606
 
Tolmetin
 
C15H15NO3
 
5509 
Major    Inter Info   
[1]
D1613
 
Tositumomab
 
NA
 
NA
Major    Inter Info   
[43], [44]
D1614
 
Tositumomab (I-131)
 
NA
 
NA
Major    Inter Info   
[43], [44]
D1625
 
Treprostinil
 
C23H34O5
 
6918140 
Major    Inter Info   
[1]
D1705
 
Vorapaxar
 
C29H33FN2O4
 
10077130 
Major    Inter Info   
[1]
D1711
 
Warfarin
 
C19H16O4
 
54678486 
Major    Inter Info   
[1]
D1718
 
Zanubrutinib
 
C27H29N5O3
 
135565884 
Major    Inter Info   
[5]
D0904
 
Lepirudin
 
C287H440N80O111S6
 
118856773 
Major    Inter Info   
[1]
D1395
 
Reteplase
 
NA
 
NA
Major    Inter Info   
[1]
D1550
 
Tenecteplase
 
NA
 
NA
Major    Inter Info   
[1]
D1669
 
Urokinase
 
NA
 
NA
Major    Inter Info   
[1]
D0211
 
Bromfenac (ophthalmic)
 
C15H12BrNO3
 
60726 
Moderate    Inter Info   
[57], [58], [59]
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Moderate    Inter Info   
[64], [65], [66]
D0361
 
Clomipramine
 
C19H23ClN2
 
2801 
Moderate    Inter Info   
[64], [65], [66]
D1769
 
Deoxycholic acid
 
C24H40O4
 
222528 
Moderate    Inter Info   
[5], [68]
D0451
 
Desvenlafaxine
 
C16H25NO2
 
125017 
Moderate    Inter Info   
[64], [65], [66]
D0457
 
Dexfenfluramine
 
C12H16F3N
 
66265 
Moderate    Inter Info   
[64], [65], [66]
D0477
 
Diclofenac (ophthalmic)
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[57], [58], [59]
D0478
 
Diclofenac (topical)
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[57], [58], [59]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Moderate    Inter Info   
[64], [65], [66]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Moderate    Inter Info   
[64], [65], [66]
D0641
 
Fenfluramine
 
C12H16F3N
 
3337 
Moderate    Inter Info   
[64], [65], [66]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Moderate    Inter Info   
[64], [65], [66]
D0681
 
Flurbiprofen (ophthalmic)
 
C15H13FO2
 
3394 
Moderate    Inter Info   
[57], [58], [59]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Moderate    Inter Info   
[64], [65], [66]
D0752
 
Hemin
 
C34H32FeN4O4
 
26945 
Moderate    Inter Info   
[72]
D0883
 
Ketorolac (ophthalmic)
 
C15H13NO3
 
3826 
Moderate    Inter Info   
[57], [58], [59]
D0920
 
Levomilnacipran
 
C15H22N2O
 
6917779 
Moderate    Inter Info   
[64], [65], [66]
D1066
 
Milnacipran
 
C15H22N2O
 
65833 
Moderate    Inter Info   
[64], [65], [66]
D1123
 
Nepafenac (ophthalmic)
 
C15H14N2O2
 
151075 
Moderate    Inter Info   
[57], [58], [59]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Moderate    Inter Info   
[64], [65], [66]
D1249
 
Pentosan polysulfate
 
C10H18O21S4
 
37720 
Moderate    Inter Info   
[5], [77]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Moderate    Inter Info   
[64], [65], [66]
D1464
 
Sibutramine
 
C17H26ClN
 
5210 
Moderate    Inter Info   
[64], [65], [66]
D1523
 
Suprofen (ophthalmic)
 
C14H12O3S
 
5359 
Moderate    Inter Info   
[57], [58], [59]
D1579
 
Ticagrelor
 
C23H28F2N6O4S
 
9871419 
Moderate    Inter Info   
[7], [82]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Moderate    Inter Info   
[64], [65], [66]
D1696
 
Vilazodone
 
C26H27N5O2
 
6918314 
Moderate    Inter Info   
[64], [65], [66]
D1708
 
Vortioxetine
 
C18H22N2S
 
9966051 
Moderate    Inter Info   
[64], [65], [66]
D0253
 
Capsicum
 
NA
 
NA
Minor    Inter Info   
[88]
D0309
 
Chamomile
 
C15H10O5
 
5280443 
Minor    Inter Info   
[88], [89], [90]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0789
 
Idelalisib
 
C22H18FN7O
 
11625818 
Moderate    Inter Info   
[73]
      Pharmacodynamic antagonistic effects
   Antagonize the effect of vaccine/toxoid Drug Num:  23
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1744
 
Bacillus calmette-guerin substrain tice live antigen
 
NA
 
NA
Major    Inter Info   
[9], [10], [11]
D1839
 
Measles virus vaccine live attenuated
 
NA
 
NA
Major    Inter Info   
[9], [10], [11]
D1849
 
Mumps virus strain B level jeryl lynn live antigen
 
NA
 
NA
Major    Inter Info   
[9], [10], [11]
D1881
 
Rotavirus vaccine
 
NA
 
NA
Major    Inter Info   
[9], [10], [11]
D1882
 
Rubella virus vaccine
 
NA
 
NA
Major    Inter Info   
[9], [10], [11]
D1890
 
Smallpox (Vaccinia) Vaccine, Live
 
NA
 
NA
Major    Inter Info   
[37], [12], [38]
D1897
 
Talimogene laherparepvec
 
NA
 
NA
Major    Inter Info   
[39]
D1914
 
Typhoid vaccine (live)
 
NA
 
NA
Major    Inter Info   
[9], [10], [11]
D1920
 
Varicella Zoster Vaccine (Recombinant)
 
NA
 
NA
Major    Inter Info   
[9], [10], [11]
D1922
 
Yellow Fever Vaccine
 
NA
 
NA
Major    Inter Info   
[9], [10], [11]
D0089
 
Anthrax vaccine
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D0366
 
Clostridium tetani toxoid antigen (formaldehyde inactivated)
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D0755
 
Hepatitis A Vaccine
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D0756
 
Hepatitis B Vaccine (Recombinant)
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D0767
 
Human papillomavirus type 11 L1 capsid protein antigen
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D0803
 
Influenza A virus A/California/7/2009 (H1N1)-like antigen (propiolactone inactivated)
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D0804
 
Influenza A virus A/Vietnam/1194/2004 (H5N1) antigen (formaldehyde inactivated)
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D0999
 
Meningococcal polysaccharide vaccine group C
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D1259
 
Pfizer-BioNTech Covid-19 Vaccine
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D1307
 
Poliovirus type 1 antigen (formaldehyde inactivated)
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D1662
 
Typhoid vaccine (inactivated)
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D1692
 
Vibrio cholerae CVD 103-HgR strain live antigen
 
NA
 
NA
Moderate    Inter Info   
[37], [52], [53]
D1838
 
Lyme disease vaccine (recombinant OspA)
 
NA
 
NA
Moderate    Inter Info   
[86]
   Antagonize the effect of probiotics Drug Num:  2
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1749
 
Bifidobacterium longum infantis
 
NA
 
NA
Moderate    Inter Info   
[54], [55], [56]
D1827
 
Lactobacillus acidophilus
 
NA
 
NA
Moderate    Inter Info   
[54], [55], [56]
   Diminish the response to diagnostic skin test antigens Drug Num:  4
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1755
 
Candida albicans
 
C29H27N2O12P
 
118855431 
Moderate    Inter Info   
[60], [61], [62]
D1765
 
Coccidioides immitis spherule
 
NA
 
NA
Moderate    Inter Info   
[60], [61], [62]
D1912
 
Trichophyton mentagrophytes
 
NA
 
NA
Moderate    Inter Info   
[60], [61], [62]
D1913
 
Tuberculin purified protein derivative
 
NA
 
NA
Moderate    Inter Info   
[60], [61], [62]
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