Details of Drug

Details of Drug

 Drug General Information (ID: D0702)
  Drug Name
Frovatriptan
  Drug Type Small molecule
  Drug Synonymous
Allegro; Auradol; Frova; Frovelan; Migard; Miguard; Rilamig; Allergo filmtabletten; SB 209509; Allergo filmtabletten(TN); Frova (TN); Frovatriptan (INN); SB-209509; (3R)-3-(methylamino)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide; (6R)-6-(methylamino)-6,7,8,9-tetrahydro-5H-carbazole-3-carboxamide; (R)-5,6,7,8-Tetrahydro-6-(methylamino)carbazole-3-carboxamide
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  Disease Class 8A80: Migraine
  Therapeutic Class Antimigraine Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C14H17N3O
  InChI 1S/C14H17N3O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18)/t9-/m1/s1
  InChIKey XPSQPHWEGNHMSK-SECBINFHSA-N
  Canonical SMILES CNC1CCC2=C(C1)C3=C(N2)C=CC(=C3)C(=O)N
  External Link
Pubchem ID 77992
CAS Number 158747-02-5
CHEBI ID 134991
TTD ID D06FPQ
INTEDE ID DR0755

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
AM006  Pharmacodynamic additive effects
BM017  CYP450 enzyme inhibition
BM022  CYP450 enzyme induction
BM038  Additive CNS depression effects
BM041  Additive hypertensive effects
BM046  Additive serotonergic effects
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Frovatriptan
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  5
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0002
 
Abametapir (topical)
 
C12H12N2
 
15664 
Moderate    Inter Info   
[146]
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Moderate    Inter Info   
[147]
D0545
 
Echinacea
 
NA
 
NA
Moderate    Inter Info   
[149]
D1432
 
Rucaparib
 
C19H18FN3O
 
9931954 
Moderate    Inter Info   
[150]
D1687
 
Vemurafenib
 
C23H18ClF2N3O3S
 
42611257 
Moderate    Inter Info   
[190]
   CYP450 enzyme induction Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1167
 
Olaparib
 
C24H23FN4O3
 
23725625 
Moderate    Inter Info   
[104], [105], [150]
      Pharmacodynamic additive effects
   Additive CNS depression effects Drug Num:  18
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0219
 
Buprenorphine
 
C29H41NO4
 
644073 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D0226
 
Butorphanol
 
C21H29NO2
 
5361092 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D0379
 
Codeine
 
C18H21NO3
 
5284371 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D0161
 
Benzhydrocodone
 
C25H25NO4
 
49836084 
Moderate    Inter Info   
[122], [123], [124]
D0470
 
Dezocine
 
C16H23NO
 
3033053 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D0493
 
Dihydrocodeine
 
C18H23NO3
 
5284543 
Moderate    Inter Info   
[122], [123], [124]
D0909
 
Levacetylmethadol
 
C23H31NO2
 
15130 
Moderate    Inter Info   
[122], [123], [124]
D1169
 
Oliceridine
 
C22H30N2O2S
 
66553195 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D1208
 
Oxymorphone
 
C17H19NO4
 
5284604 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D0772
 
Hydrocodone
 
C18H21NO3
 
5284569 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D0776
 
Hydromorphone
 
C17H19NO3
 
5284570 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D0923
 
Levorphanol
 
C17H23NO
 
5359272 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D1017
 
Methadone
 
C21H27NO
 
4095 
Moderate    Inter Info   
[122], [126], [131], [124], [88], [123], [49], [140], [17], [31], [141], [48], [59], [85], [133], [127], [33], [142], [53], [135], [130], [129], [19], [143], [99], [132], [136], [87], [144], [134], [145], [139], [125], [128], [35], [5], [11], [137], [138], [94]
D1089
 
Morphine
 
C17H19NO3
 
5288826 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D1090
 
Morphine (liposomal)
 
C17H19NO3
 
5288826 
Moderate    Inter Info   
[122], [123], [124]
D1100
 
Nalbuphine
 
C21H27NO4
 
5311304 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D1203
 
Oxycodone
 
C18H21NO4
 
5284603 
Moderate    Inter Info   
[122], [123], [124], [125], [126], [48], [49], [17], [127], [128], [129], [35], [130], [31], [19], [5], [59], [131], [85], [132], [99], [133], [53], [134], [135], [11], [88], [136], [137], [138], [94], [87], [139], [140], [141], [142], [33], [143], [144], [145]
D1596
 
Tizanidine
 
C9H8ClN5S
 
5487 
Moderate    Inter Info   
[191]
   Additive hypertensive effects Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0538
 
Droxidopa
 
C9H11NO5
 
92974 
Moderate    Inter Info   
[148]
   Additive serotonergic effects Drug Num:  39
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0514
 
Dolasetron
 
C19H20N2O3
 
3033818 
Major    Inter Info   
[103], [104], [105], [106], [107], [108], [109]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0641
 
Fenfluramine
 
C12H16F3N
 
3337 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0646
 
Fentanyl
 
C22H28N2O
 
3345 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0446
 
Desipramine
 
C18H22N2
 
2995 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0451
 
Desvenlafaxine
 
C16H25NO2
 
125017 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0457
 
Dexfenfluramine
 
C12H16F3N
 
66265 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0853
 
Isocarboxazid
 
C12H13N3O2
 
3759 
Major    Inter Info   
[11], [110], [111], [22], [48], [53], [57], [112], [94]
D0897
 
Lasmiditan
 
C19H18F3N3O2
 
11610526 
Major    Inter Info   
[113], [114], [115]
D0920
 
Levomilnacipran
 
C15H22N2O
 
6917779 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0952
 
Lorcaserin
 
C11H14ClN
 
11658860 
Major    Inter Info   
[116]
D1036
 
Methylene blue
 
C16H18ClN3S
 
6099 
Major    Inter Info   
[11], [110], [111], [22], [48], [53], [57], [112], [94]
D1066
 
Milnacipran
 
C15H22N2O
 
65833 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [104], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1200
 
Oxitriptan
 
C11H12N2O3
 
439280 
Major    Inter Info   
[13], [61], [63]
D1345
 
Procarbazine
 
C12H19N3O
 
4915 
Major    Inter Info   
[11], [110], [111], [22], [48], [53], [57], [112], [94]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1464
 
Sibutramine
 
C17H26ClN
 
5210 
Major    Inter Info   
[11], [24], [26], [34], [48], [53], [57], [74], [94]
D1535
 
Tapentadol
 
C14H23NO
 
9838022 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1696
 
Vilazodone
 
C26H27N5O2
 
6918314 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1708
 
Vortioxetine
 
C18H22N2S
 
9966051 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D0738
 
Granisetron
 
C18H24N4O
 
5284566 
Major    Inter Info   
[103], [104], [105], [106], [107], [108], [109]
D0933
 
Linezolid
 
C16H20FN3O4
 
441401 
Major    Inter Info   
[7], [8], [10], [105], [117], [16], [25], [118], [29], [30], [38], [43], [119], [48], [53], [54], [55], [120], [57], [60], [84], [90], [93], [94], [95], [96], [98], [102], [121]
D1075
 
Mirtazapine
 
C17H19N3
 
4205 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1181
 
Ondansetron
 
C18H19N3O
 
4595 
Major    Inter Info   
[103], [104], [105], [106], [107], [108], [109]
D1216
 
Palonosetron
 
C19H24N2O
 
6337614 
Major    Inter Info   
[103], [104], [105], [106], [107], [108], [109]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1263
 
Phenelzine
 
C8H12N2
 
3675 
Major    Inter Info   
[11], [110], [111], [22], [48], [53], [57], [112], [94]
D1616
 
Tramadol
 
C16H25NO2
 
33741 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1620
 
Tranylcypromine
 
C9H11N
 
19493 
Major    Inter Info   
[11], [110], [111], [22], [48], [53], [57], [112], [94]
D1624
 
Trazodone
 
C19H22ClN5O
 
5533 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Major    Inter Info   
[4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99], [100], [101], [102]
D1211
 
Ozanimod
 
C23H24N4O3
 
52938427 
Moderate    Inter Info   
[151], [152], [153], [154], [155], [156], [157], [158], [11], [12], [13], [14], [159], [110], [160], [161], [162], [20], [111], [22], [135], [163], [164], [165], [166], [167], [168], [169], [170], [171], [48], [50], [52], [53], [57], [61], [112], [172], [173], [63], [64], [65], [66], [67], [68], [70], [71], [72], [174], [73], [77], [78], [79], [80], [81], [175], [82], [83], [176], [89], [177], [178], [179], [180], [181], [94], [182], [183], [184], [185], [186], [187]
D1455
 
Selegiline
 
C13H17N
 
26757 
Moderate    Inter Info   
[53], [83], [94]
D1502
 
St. John's Wort
 
NA
 
NA
Moderate    Inter Info   
[188], [189]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  13
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0041
 
Almotriptan
 
C17H25N3O2S
 
123606 
Major    Inter Info   
[1], [2], [3]
D0228
 
Cabergoline
 
C26H37N5O2
 
54746 
Major    Inter Info   
[1], [2], [3]
D0494
 
Dihydroergotamine
 
C33H37N5O5
 
10531 
Major    Inter Info   
[1], [2], [3]
D0557
 
Eletriptan
 
C22H26N2O2S
 
77993 
Major    Inter Info   
[1], [2], [3]
D0593
 
Ergotamine
 
C33H35N5O5
 
8223 
Major    Inter Info   
[1], [2], [3]
D0212
 
Bromocriptine
 
C32H40BrN5O5
 
31101 
Major    Inter Info   
[1], [2], [3]
D0592
 
Ergometrine
 
C19H23N3O2
 
443884 
Major    Inter Info   
[1], [2], [3]
D1037
 
Methylergometrine
 
C20H25N3O2
 
8226 
Major    Inter Info   
[1], [2], [3]
D1043
 
Methysergide
 
C21H27N3O2
 
9681 
Major    Inter Info   
[1], [2], [3]
D1110
 
Naratriptan
 
C17H25N3O2S
 
4440 
Major    Inter Info   
[1], [2], [3]
D1419
 
Rizatriptan
 
C15H19N5
 
5078 
Major    Inter Info   
[1], [2], [3]
D1521
 
Sumatriptan
 
C14H21N3O2S
 
5358 
Major    Inter Info   
[1], [2], [3]
D1728
 
Zolmitriptan
 
C16H21N3O2
 
60857 
Major    Inter Info   
[1], [2], [3]
References
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2 Product Information. Parlodel (bromocriptine). Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
3 Product Information. Maxalt (rizatriptan). Merck &amp Co, Inc, West Point, PA.
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63 Product Information. Brintellix (vortioxetine). Takeda Pharmaceuticals America, Lincolnshire, IL.
64 Product Information. Celexa (citalopram). Forest Pharmaceuticals, St. Louis, MO.
65 Product Information. Cymbalta (duloxetine). Lilly, Eli and Company, Indianapolis, IN.
66 Product Information. D.H.E. 45 (dihydroergotamine). Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
67 Product Information. Effexor (venlafaxine). Wyeth-Ayerst Laboratories, Philadelphia, PA.
68 Product Information. Fetzima (levomilnacipran). Forest Pharmaceuticals, St. Louis, MO.
69 Product Information. Flexeril (cyclobenzaprine). Merck & Co, Inc, West Point, PA.
70 Product Information. Imitrex (sumatriptan). Glaxo Wellcome, Research Triangle Park, NC.
71 Product Information. Lexapro (escitalopram). Forest Pharmaceuticals, St. Louis, MO.
72 Product Information. Luvox (fluvoxamine). Solvay Pharmaceuticals Inc, Marietta, GA.
73 Product Information. Maxalt (rizatriptan). Merck & Co, Inc, West Point, PA.
74 Product Information. Meridia (sibutramine). Knoll Pharmaceutical Company, Whippany, NJ.
75 Product Information. Nucynta (tapentadol). PriCara Pharmaceuticals, Raritan, NJ.
76 Product Information. Oleptro (traZODone). Labopharm Inc, Laval, AL.
77 Product Information. Paxil (paroxetine). GlaxoSmithKline, Research Triangle Park, NC.
78 Product Information. Pristiq (desvenlafaxine). Wyeth Laboratories, Philadelphia, PA.
79 Product Information. Prozac (fluoxetine). Dista Products Company, Indianapolis, IN.
80 Product Information. Savella (milnacipran). Forest Pharmaceuticals, St. Louis, MO.
81 Product Information. Viibryd (vilazodone). Trovis Pharmaceuticals LLC, New Haven, CT.
82 Product Information. Zoloft (sertraline). Roerig Division, New York, NY.
83 Product Information. Zomig (zolmitriptan). Zeneca Pharmaceuticals, Wilmington, DE.
84 Product Information. Zyvox (linezolid) Pharmacia and Upjohn, Kalamazoo, MI.
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107 Product Information. Aloxi (palonosetron). MGI Pharma Inc, Minnetonka, MN.
108 Product Information. Anzemet (dolasetron). Hoechst Marion-Roussel Inc, Kansas City, MO.
109 Product Information. Sancuso (granisetron). ProStrakan Group, Bedminster, NJ.
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175 Product Information. Zeposia (ozanimod). Celgene Corporation, Summit, NJ.
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189 Product Information. Amerge (naratriptan). Glaxo Wellcome, Research Triangle Park, NC.
190 Product Information. Zelboraf (vemurafenib). Genentech, South San Francisco, CA.
191 Product Information. Zanaflex (tizanidine). Acorda Therapeutics, Hawthorne, NY.