Details of Drug

Details of Drug

 Drug General Information (ID: D0660)
  Drug Name
Finasteride
  Drug Type Small molecule
  Drug Synonymous
Andozac; Eucoprost; FIT; Finasterida; Finasteridum; Finastid; Finpecia; Propecia; Propeshia; Proscar; Prostide; Cahill May Roberts Brand of Finasteride; Chibro Proscar; Frosst Iberica Brand of Finasteride; Lipha Brand of Finasteride; MSD Brand of Finasteride; MSD Chibropharm Brand of Finasteride; MK 0906; MK 906; MK906; Merck Brand 1 of Finasteride; Merck Brand 2 of Finasteride; Merck Frosst Brand 1 of Finasteride; Merck Frosst Brand 2 of Finasteride; Alternova (TN); Appecia (TN); Chibro-Proscar; Finalo (TN); Finara (TN); Finast (TN); Finasterid (TN); Finasterid IVAX (TN); Finasterida [INN-Spanish]; Finasteridum [INN-Latin]; Finax (TN); Fincar (TN); Finpecia (TN); Gefina (TN); KS-1058; MK-0906; MK-906; Merck Sharp & Dhome Brand 2 of Finasteride; Merck Sharp & Dohme Brand 1 of Finasteride; Propecia (TN); Proscar (TN); Prosteride (TN); YM-152; Finasteride (USP/INN); Finasteride [USAN:INN:BAN]; L-652,931; Proscar, Propecia, Finasteride; N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-en-17beta-carboxamide; N-tert-Butyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide; N-(2-methyl-2-propyl)-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide; N-(2-Methyl-2-propyl)-3-oxo-4-aza-5-alpha-androst-1-ene-17-beta-carboxamide; (1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-tert-butyl-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(1,1-dimethylethyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(tert-butyl)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide; (5alpha,17beta)-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide; 17beta-(N-tert-butylcarbamoyl)-4-aza-5 alpha-androst-1-en-3-one
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  Disease Class GA90: Prostate hyperplasia
  Therapeutic Class Antihyperplasia Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C23H36N2O2
  InChI 1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
  InChIKey DBEPLOCGEIEOCV-WSBQPABSSA-N
  Canonical SMILES CC12CCC3C(C1CCC2C(=O)NC(C)(C)C)CCC4C3(C=CC(=O)N4)C
  External Link
Pubchem ID 57363
CAS Number 98319-26-7
CHEBI ID 5062
TTD ID D08IWD
INTEDE ID DR0695

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
AM006  Pharmacodynamic additive effects
BM017  CYP450 enzyme inhibition
BM022  CYP450 enzyme induction
BM024  Competitive inhibition of metabolic enzyme
BM064  Increased risk of hypoglycemia
  Relation Graph
 Full list of drugs interacting with Finasteride
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  14
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0497
 
Diltiazem
 
C22H26N2O4S
 
39186 
Moderate    Inter Info   
[1], [2], [3], [4], [5]
D0002
 
Abametapir (topical)
 
C12H12N2
 
15664 
Moderate    Inter Info   
[6]
D0543
 
Duvelisib
 
C22H17ClN6O
 
50905713 
Moderate    Inter Info   
[7]
D0699
 
Fostamatinib
 
C23H26FN6O9P
 
11671467 
Moderate    Inter Info   
[8]
D0896
 
Larotrectinib
 
C21H22F2N6O2
 
46188928 
Moderate    Inter Info   
[12], [13], [14]
D0899
 
Lefamulin
 
C28H45NO5S
 
25185057 
Moderate    Inter Info   
[15], [16], [17]
D1444
 
Saquinavir
 
C38H50N6O5
 
441243 
Moderate    Inter Info   
[18], [19]
D1459
 
Selpercatinib
 
C29H31N7O3
 
134436906 
Moderate    Inter Info   
[13], [20]
D0667
 
Fluconazole
 
C13H12F2N6O
 
3365 
Moderate    Inter Info   
[25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Moderate    Inter Info   
[43], [44]
D0867
 
Itraconazole
 
C35H38Cl2N8O4
 
55283 
Moderate    Inter Info   
[45], [12], [46], [47], [48], [49], [50], [51], [52]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Moderate    Inter Info   
[53]
D1119
 
Nelfinavir
 
C32H45N3O4S
 
64143 
Moderate    Inter Info   
[54]
D1706
 
Voriconazole
 
C16H14F3N5O
 
71616 
Moderate    Inter Info   
[12], [13], [55]
   CYP450 enzyme induction Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1493
 
Somapacitan
 
C54H95N13O20S2
 
129894493 
Moderate    Inter Info   
[12], [13], [21]
D1495
 
Somatrem
 
C43H72N14O14
 
5487805 
Moderate    Inter Info   
[12], [13], [22], [21]
D1494
 
Somatotropin
 
NA
 
NA
Moderate    Inter Info   
[12], [13], [21]
   Competitive inhibition of metabolic enzyme Drug Num:  3
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1549
 
Temsirolimus
 
C56H87NO16
 
6918289 
Moderate    Inter Info   
[23], [24]
D1476
 
Sirolimus
 
C51H79NO13
 
5284616 
Moderate    Inter Info   
[23], [24]
D1526
 
Tacrolimus
 
C44H69NO12
 
445643 
Moderate    Inter Info   
[23], [24]
      Pharmacodynamic additive effects
   Increased risk of hypoglycemia Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0723
 
Ginseng
 
C42H66O17
 
420552 
Moderate    Inter Info   
[9], [10], [11]
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