Details of Drug

Details of Drug

 Drug General Information (ID: D0652)
  Drug Name
Ferumoxides
  Drug Type Small molecule
  Drug Synonymous
AMI-25; 119683-68-0; Feridex; Feridex IV; Superparamagnetic iron oxide; UNII-G6N3J05W84; Ferumoxides [USAN:USP:BAN]; CCRIS 6722; HSDB 8072; AC1O5DID; G6N3J05W84; iron(2+); iron(3+); Iron oxide crystal is inverse spinel (X-ray data); Fe(II) and Fe(III) are present (Mossbauer Spectroscopy; Physical form is a colloidal particle of nonstoichiometric
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  Disease Class 2C12: Liver cancer; DB90-DB9Z: Liver disease
  Therapeutic Class Mri Contrast Media
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula Fe3O4
  InChI 1S/3Fe.4O/q+2;2*+3;4*-2
  InChIKey WTFXARWRTYJXII-UHFFFAOYSA-N
  Canonical SMILES [O-2].[O-2].[O-2].[O-2].[Fe+2].[Fe+3].[Fe+3]
  External Link
Pubchem ID 6432052
CAS Number 119683-68-0
TTD ID D08QAC

Drug-Drug Interaction Network
  Sunburst Graph
AM003  Affected organization distribution
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM013  Competitive binding of plasma proteins
BM072  Increased risk of nephrotoxicity
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Ferumoxides
      Affected organization distribution
   Competitive binding of plasma proteins Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0708
 
Gallium chloride Ga-67
 
Cl3Ga
 
73415785 
Moderate    Inter Info   
[4]
      Pharmacodynamic additive effects
   Increased risk of nephrotoxicity Drug Num:  2
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1826
 
Iopanoic acid
 
C11H12I3NO2
 
3735 
Moderate    Inter Info   
[5], [6], [7]
D1915
 
Tyropanoic acid
 
C15H18I3NO3
 
5611 
Moderate    Inter Info   
[5], [6], [7]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1776
 
Dimercaprol
 
C3H8OS2
 
3080 
Major    Inter Info   
[1], [2], [3]
References
1 Desmedt S, Spinewine A, Jadoul M, Henrard S, Wouters D, Dalleur O. Impact of a clinical decision support system for drug dosage in patients with renal failure.?Int J Clin Pharm. 2018;40(5):1225-1233. [PMID: 29785684]
2 Chenoweth MB "Clinical uses of metal-binding drugs." Clin Pharmacol Ther 9 (1968): 365-87. [PMID: 4984845]
3 Product Information. BAL in Oil (dimercaprol). Becton Dickinson, Franklin Lakes, NJ.
4 Product Information. Gallium Citrate Ga-67 (gallium citrate 67 Ga (gallium citrate 67Ga)). Bristol-Myers Squibb, Princeton, NJ.
5 Product Information. Ultravist (iopromide). Berlex, Richmond, CA.
6 Product Information. Visipaque (iodixanol). Nycomed Inc, Princeton, NJ.
7 Product Information. Omniscan (gadodiamide). Novation, Irving, TX.