Details of Drug

Drug General Information (ID: D0638)
Drug Name	Fedratinib
Drug Type	Small molecule
Drug Synonymous	TG101348 Click to Show/Hide
Disease Class	2A20: Myeloproliferative neoplasm
Therapeutic Class	Multikinase Inhibitors
Structure
Structure	3D Structure		2D Structure
Formula	C27H36N6O3S
InChI	1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)
InChIKey	JOOXLOJCABQBSG-UHFFFAOYSA-N
Canonical SMILES	CC1=CN=C(N=C1NC2=CC(=CC=C2)S(=O)(=O)NC(C)(C)C)NC3=CC=C(C=C3)OCCN4CCCC4
External Link
	Pubchem ID	16722836
	CAS Number	936091-26-8
	CHEBI ID	91408
	TTD ID	D0G8BM

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM004 Affected intra/extra-hepatic metabolism AM006 Pharmacodynamic additive effects BM017 CYP450 enzyme inhibition BM022 CYP450 enzyme induction BM044 Additive myelosuppressive effects BM050 Increased risk of bleeding BM055 Increased risk of hepatotoxicity
Relation Graph

Full list of drugs interacting with Fedratinib
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 331
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0008		Acalabrutinib	C26H23N7O2	71226662	Major		Inter Info	[1]
D0035		Alfentanil	C21H32N6O3	51263	Major		Inter Info	[2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15]
D0080		Amprenavir	C25H35N3O6S	65016	Major		Inter Info	[16], [17]
D0116		Atazanavir	C38H52N6O7	148192	Major		Inter Info	[16], [17]
D0128		Avanafil	C23H26ClN7O3	9869929	Major		Inter Info	[24]
D0192		Boceprevir	C27H45N5O5	10324367	Major		Inter Info	[16], [17]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Major		Inter Info	[26], [16], [27], [28]
D0202		Brexpiprazole	C25H27N3O2S	11978813	Major		Inter Info	[29]
D0204		Brigatinib	C29H39ClN7O2P	68165256	Major		Inter Info	[26], [16], [30]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Major		Inter Info	[16], [17]
D0336		Cilostazol	C20H27N5O2	2754	Major		Inter Info	[16], [32], [33], [34]
D0342		Cisapride	C23H29ClFN3O4	6917698	Major		Inter Info	[35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45]
D0345		Citalopram	C20H21FN2O	2771	Major		Inter Info	[46], [47], [48]
D0349		Clarithromycin	C38H69NO13	84029	Major		Inter Info	[16], [17]
D0375		Cobicistat	C40H53N7O5S2	25151504	Major		Inter Info	[16], [17]
D0376		Cobimetinib	C21H21F3IN3O2	16222096	Major		Inter Info	[51]
D0386		Conivaptan	C32H26N4O2	151171	Major		Inter Info	[16], [17]
D0436		Deflazacort	C25H31NO6	189821	Major		Inter Info	[16], [57]
D0439		Delavirdine	C22H28N6O3S	5625	Major		Inter Info	[16], [17]
D0559		Eliglustat	C23H36N2O4	23652731	Major		Inter Info	[60], [61]
D0569		Encorafenib	C22H27ClFN7O4S	50922675	Major		Inter Info	[62]
D0577		Entrectinib	C31H34F2N6O2	25141092	Major		Inter Info	[26], [16], [63]
D0629		Everolimus	C53H83NO14	6442177	Major		Inter Info	[64]
D0129		Avapritinib	C26H27FN10	118023034	Major		Inter Info	[16], [65]
D0161		Benzhydrocodone	C25H25NO4	49836084	Major		Inter Info	[66], [67], [68]
D0962		Lurbinectedin	C41H44N4O10S	57327016	Major		Inter Info	[70]
D1242		Pemigatinib	C24H27F2N5O4	86705695	Major		Inter Info	[16], [71]
D1459		Selpercatinib	C29H31N7O3	134436906	Major		Inter Info	[16], [72]
D1538		Tazemetostat	C34H44N4O4	66558664	Major		Inter Info	[73]
D1653		Troleandomycin	C41H67NO15	202225	Major		Inter Info	[16], [17]
D1718		Zanubrutinib	C27H29N5O3	135565884	Major		Inter Info	[52]
D0646		Fentanyl	C22H28N2O	3345	Major		Inter Info	[26], [74], [75], [76], [28], [77], [14]
D0665		Flibanserin	C20H21F3N4O	6918248	Major		Inter Info	[78]
D0692		Fosamprenavir	C25H36N3O9PS	131536	Major		Inter Info	[16], [17]
D0745		Guanfacine	C9H9Cl2N3O	3519	Major		Inter Info	[16], [79]
D0749		Halofantrine	C26H30Cl2F3NO	37393	Major		Inter Info	[80], [81], [82], [83], [84]
D0772		Hydrocodone	C18H21NO3	5284569	Major		Inter Info	[66], [67]
D0789		Idelalisib	C22H18FN7O	11625818	Major		Inter Info	[16], [17]
D0799		Indinavir	C36H47N5O4	5362440	Major		Inter Info	[16], [17]
D0867		Itraconazole	C35H38Cl2N8O4	55283	Major		Inter Info	[16], [17]
D0868		Ivabradine	C27H36N2O5	132999	Major		Inter Info	[16], [87], [88]
D0869		Ivacaftor	C24H28N2O3	16220172	Major		Inter Info	[16], [89], [90], [91], [92]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Major		Inter Info	[16], [17]
D0901		Lemborexant	C22H20F2N4O2	56944144	Major		Inter Info	[26], [96]
D0909		Levacetylmethadol	C23H31NO2	15130	Major		Inter Info	[97], [98]
D0944		Lomitapide	C39H37F6N3O2	9853053	Major		Inter Info	[26], [99], [28]
D0946		Lonafarnib	C27H31Br2ClN4O2	148195	Major		Inter Info	[98]
D0959		Lumateperone	C24H28FN3O	21302490	Major		Inter Info	[100]
D1104		Naloxegol	C34H53NO11	56959087	Major		Inter Info	[16], [102]
D1117		Nefazodone	C25H32ClN5O2	4449	Major		Inter Info	[16], [17]
D1119		Nelfinavir	C32H45N3O4S	64143	Major		Inter Info	[16], [17]
D1124		Neratinib	C30H29ClN6O3	9915743	Major		Inter Info	[103], [26], [104]
D1203		Oxycodone	C18H21NO4	5284603	Major		Inter Info	[26], [16], [106]
D1292		Pimozide	C28H29F2N3O	16362	Major		Inter Info	[26], [108], [38], [109], [110], [111], [112], [113], [28]
D1315		Posaconazole	C37H42F2N8O4	468595	Major		Inter Info	[16], [17]
D1383		Ranolazine	C24H33N3O4	56959	Major		Inter Info	[117]
D1415		Ritonavir	C37H48N6O5S2	392622	Major		Inter Info	[16], [17]
D1444		Saquinavir	C38H50N6O5	441243	Major		Inter Info	[16], [17]
D1460		Selumetinib	C17H15BrClFN4O3	10127622	Major		Inter Info	[122]
D1471		Simeprevir	C38H47N5O7S2	24873435	Major		Inter Info	[26], [123], [28]
D1474		Siponimod	C29H35F3N2O3	44599207	Major		Inter Info	[26], [124]
D1496		Sonidegib	C26H26F3N3O3	24775005	Major		Inter Info	[125]
D1524		Suvorexant	C23H23ClN6O2	24965990	Major		Inter Info	[126]
D1533		Tamoxifen	C26H29NO	2733526	Major		Inter Info	[127], [128], [129], [130], [131], [132], [133], [134], [135], [136], [137], [138], [139], [140], [141], [142], [143], [144], [145], [146], [147], [148], [149], [150], [151], [152], [61], [153], [154], [155], [156], [157], [158], [159], [160]
D1541		Telaprevir	C36H53N7O6	3010818	Major		Inter Info	[16], [17]
D1544		Telithromycin	C43H65N5O10	3002190	Major		Inter Info	[16], [17]
D1574		Thioridazine	C21H26N2S2	5452	Major		Inter Info	[161], [162], [163], [110], [164], [165], [166], [167], [168], [169], [61], [170], [171]
D1660		Tucatinib	C26H24N8O2	51039094	Major		Inter Info	[16], [17]
D1688		Venetoclax	C45H50ClN7O7S	49846579	Major		Inter Info	[26], [16], [175]
D1706		Voriconazole	C16H14F3N5O	71616	Major		Inter Info	[16], [17]
D0002		Abametapir (topical)	C12H12N2	15664	Moderate		Inter Info	[177]
D0006		Abemaciclib	C27H32F2N8	46220502	Moderate		Inter Info	[178]
D0007		Abiraterone	C24H31NO	132971	Moderate		Inter Info	[179], [180], [17]
D0028		Albendazole	C12H15N3O2S	2082	Moderate		Inter Info	[16], [17]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[181]
D0038		Aliskiren	C30H53N3O6	5493444	Moderate		Inter Info	[93], [16], [182], [183]
D0045		Alprazolam	C17H13ClN4	2118	Moderate		Inter Info	[16], [17]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[16], [17]
D0068		Amitriptyline	C20H23N	2160	Moderate		Inter Info	[16], [17]
D0069		Amlodipine	C20H25ClN2O5	2162	Moderate		Inter Info	[93], [26], [16], [184], [185]
D0072		Amoxapine	C17H16ClN3O	2170	Moderate		Inter Info	[16], [17]
D0096		Apixaban	C25H25N5O4	10182969	Moderate		Inter Info	[16], [186], [187]
D0100		Aprepitant	C23H21F7N4O3	135413536	Moderate		Inter Info	[188], [189]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[190]
D0108		Artemether	C16H26O5	68911	Moderate		Inter Info	[191], [119], [17]
D0115		Astemizole	C28H31FN4O	2247	Moderate		Inter Info	[16], [17]
D0119		Atomoxetine	C17H21NO	54841	Moderate		Inter Info	[192], [187], [193]
D0120		Atorvastatin	C33H35FN2O5	60823	Moderate		Inter Info	[194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [38], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [187], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254]
D0133		Axitinib	C22H18N4OS	6450551	Moderate		Inter Info	[16], [255]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Moderate		Inter Info	[16], [17]
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [87], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283]
D0181		Bictegravir	C21H18F3N3O5	90311989	Moderate		Inter Info	[26], [16], [286]
D0193		Bortezomib	C19H25BN4O4	387447	Moderate		Inter Info	[16], [17]
D0212		Bromocriptine	C32H40BrN5O5	31101	Moderate		Inter Info	[16], [17]
D0215		Budesonide	C25H34O6	5281004	Moderate		Inter Info	[258], [26], [16], [287], [288], [289], [261], [290], [291], [272], [292], [293], [294], [295], [274], [275]
D0216		Budesonide (nasal)	C25H34O6	5281004	Moderate		Inter Info	[258], [26], [16]
D0219		Buprenorphine	C29H41NO4	644073	Moderate		Inter Info	[296]
D0230		Cabozantinib	C28H24FN3O5	25102847	Moderate		Inter Info	[297]
D0251		Capmatinib	C23H17FN6O	25145656	Moderate		Inter Info	[299]
D0263		Carisoprodol	C12H24N2O4	2576	Moderate		Inter Info	[16], [17]
D0267		Carvedilol	C24H26N2O4	2585	Moderate		Inter Info	[16], [17]
D0303		Cerivastatin	C26H34FNO5	446156	Moderate		Inter Info	[194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [38], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [187], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254]
D0308		Cevimeline	C10H17NOS	83898	Moderate		Inter Info	[300]
D0313		Chloramphenicol	C11H12Cl2N2O5	5959	Moderate		Inter Info	[16], [301], [302]
D0320		Chloroquine	C18H26ClN3	2719	Moderate		Inter Info	[26]
D0323		Chlorpheniramine	C16H19ClN2	2725	Moderate		Inter Info	[16], [17]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[16], [17]
D0337		Cimetidine	C10H16N6S	2756	Moderate		Inter Info	[16], [301], [302]
D0338		Cinacalcet	C22H22F3N	156419	Moderate		Inter Info	[16], [17]
D0356		Clobazam	C16H13ClN2O2	2789	Moderate		Inter Info	[303]
D0361		Clomipramine	C19H23ClN2	2801	Moderate		Inter Info	[16], [17]
D0362		Clonazepam	C15H10ClN3O3	2802	Moderate		Inter Info	[16], [17]
D0364		Clopidogrel	C16H16ClNO2S	60606	Moderate		Inter Info	[305], [306], [307], [308], [309], [310], [311], [312], [313], [314], [315], [316], [317], [318], [319], [320], [321], [322], [323]
D0365		Clorazepic acid	C16H11ClN2O3	2809	Moderate		Inter Info	[191], [119], [17]
D0379		Codeine	C18H21NO3	5284371	Moderate		Inter Info	[324], [325], [326], [327], [328], [329], [61], [330], [331], [332], [333], [334], [335]
D0387		Conjugated estrogens	C18H21NaO5S	45357473	Moderate		Inter Info	[16], [17]
D0402		Cyclosporine	C62H111N11O12	5284373	Moderate		Inter Info	[16], [17]
D0408		Daclatasvir	C40H50N8O6	25154714	Moderate		Inter Info	[26], [16], [336]
D0424		Darifenacin	C28H30N2O2	444031	Moderate		Inter Info	[337], [187]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[338]
D0446		Desipramine	C18H22N2	2995	Moderate		Inter Info	[16], [17]
D0452		Deutetrabenazine	C19H27NO3	73437646	Moderate		Inter Info	[16], [17]
D0454		Dexamethasone (nasal)	C22H29FO5	5743	Moderate		Inter Info	[261], [262], [276]
D0455		Dexamethasone (ophthalmic)	C22H29FO5	5743	Moderate		Inter Info	[261], [262], [276]
D0457		Dexfenfluramine	C12H16F3N	66265	Moderate		Inter Info	[16], [17]
D0466		Dextromethorphan	C18H25NO	5360696	Moderate		Inter Info	[26], [16], [343], [107], [187], [344]
D0467		Dextropropoxyphene	C22H29NO2	10100	Moderate		Inter Info	[191], [119], [17]
D0493		Dihydrocodeine	C18H23NO3	5284543	Moderate		Inter Info	[191], [119], [17]
D0494		Dihydroergotamine	C33H37N5O5	10531	Moderate		Inter Info	[345], [346], [347], [348], [349], [38], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368]
D0508		Disopyramide	C21H29N3O	3114	Moderate		Inter Info	[16], [17]
D0511		Docetaxel	C43H53NO14	148124	Moderate		Inter Info	[369], [26], [16], [370], [371], [372], [373], [374], [375]
D0513		Dofetilide	C19H27N3O5S2	71329	Moderate		Inter Info	[376]
D0525		Doxepin	C19H21NO	667477	Moderate		Inter Info	[16], [17]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[16], [17]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Moderate		Inter Info	[191], [119], [17]
D0534		Dronedarone	C31H44N2O5S	208898	Moderate		Inter Info	[377]
D0539		Duloxetine	C18H19NOS	60835	Moderate		Inter Info	[378], [379]
D0543		Duvelisib	C22H17ClN6O	50905713	Moderate		Inter Info	[380]
D0557		Eletriptan	C22H26N2O2S	77993	Moderate		Inter Info	[381]
D0592		Ergometrine	C19H23N3O2	443884	Moderate		Inter Info	[351], [353], [364]
D0593		Ergotamine	C33H35N5O5	8223	Moderate		Inter Info	[345], [346], [347], [348], [349], [38], [350], [351], [352], [353], [354], [355], [356], [357], [358], [359], [360], [361], [362], [363], [364], [365], [366], [367], [368]
D0599		Escitalopram	C20H21FN2O	146570	Moderate		Inter Info	[93], [26], [16], [383], [384], [385], [386], [387], [388], [389], [390], [391], [392]
D0603		Esomeprazole	C17H19N3O3S	9568614	Moderate		Inter Info	[16], [17]
D0604		Estazolam	C16H11ClN4	3261	Moderate		Inter Info	[16], [17]
D0605		Esterified estrogens	NA	NA	Moderate		Inter Info	[16], [17]
D0606		Estradiol	C18H24O2	5757	Moderate		Inter Info	[16], [17]
D0607		Estradiol (topical)	C18H24O2	5757	Moderate		Inter Info	[191], [119], [17]
D0609		Estrone	C18H22O2	5870	Moderate		Inter Info	[16], [17]
D0610		Estrone sulfate	C18H22O5S	3001028	Moderate		Inter Info	[191], [119], [17]
D0611		Estrone sulfate (topical)	C18H22O5S	3001028	Moderate		Inter Info	[191], [119], [17]
D0612		Eszopiclone	C17H17ClN6O3	969472	Moderate		Inter Info	[393], [394], [395], [16], [38], [396], [397]
D0619		Ethinylestradiol	C20H24O2	5991	Moderate		Inter Info	[191], [119], [17]
D0626		Etonogestrel	C22H28O2	6917715	Moderate		Inter Info	[16], [17]
D0627		Etoposide	C29H32O13	36462	Moderate		Inter Info	[16], [17]
D0571		Enfortumab vedotin	NA	NA	Moderate		Inter Info	[16], [398], [399], [400]
D0684		Fluticasone (nasal)	C22H27F3O4S	5311101	Moderate		Inter Info	[26], [86], [401]
D0896		Larotrectinib	C21H22F2N6O2	46188928	Moderate		Inter Info	[26], [16], [402]
D1324		Pralsetinib	C27H32FN9O2	129073603	Moderate		Inter Info	[403]
D1409		Ripretinib	C24H21BrFN5O2	71584930	Moderate		Inter Info	[26], [407]
D1663		Ubrogepant	C29H26F3N5O3	68748835	Moderate		Inter Info	[409]
D1666		Upadacitinib	C17H19F3N6O	58557659	Moderate		Inter Info	[410]
D1709		Voxelotor	C19H19N3O3	71602803	Moderate		Inter Info	[16], [17]
D0640		Felodipine	C18H19Cl2NO4	3333	Moderate		Inter Info	[16], [17]
D0641		Fenfluramine	C12H16F3N	3337	Moderate		Inter Info	[16], [17]
D0642		Fenofibrate	C20H21ClO4	3339	Moderate		Inter Info	[16], [17]
D0655		Fesoterodine	C26H37NO3	6918558	Moderate		Inter Info	[411]
D0664		Flecainide	C17H20F6N2O3	3356	Moderate		Inter Info	[16], [17]
D0667		Fluconazole	C13H12F2N6O	3365	Moderate		Inter Info	[16], [301], [17]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [87], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283]
D0672		Flunisolide	C24H31FO6	82153	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [87], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283]
D0673		Flunisolide (nasal)	C24H31FO6	82153	Moderate		Inter Info	[261], [262], [276]
D0674		Fluorometholone (ophthalmic)	C22H29FO4	9878	Moderate		Inter Info	[261], [262], [276]
D0676		Fluoxetine	C17H18F3NO	3386	Moderate		Inter Info	[16], [17]
D0678		Fluphenazine	C22H26F3N3OS	3372	Moderate		Inter Info	[16], [17]
D0679		Flurazepam	C21H23ClFN3O	3393	Moderate		Inter Info	[16], [17]
D0687		Fluvoxamine	C15H21F3N2O2	5324346	Moderate		Inter Info	[16], [301], [17]
D0707		Galantamine	C17H21NO3	9651	Moderate		Inter Info	[16], [17]
D0713		Gefitinib	C22H24ClFN4O3	123631	Moderate		Inter Info	[412], [413]
D0720		Gilteritinib	C29H44N8O3	49803313	Moderate		Inter Info	[16], [414]
D0725		Glasdegib	C21H22N6O	25166913	Moderate		Inter Info	[415]
D0738		Granisetron	C18H24N4O	5284566	Moderate		Inter Info	[16], [17]
D0750		Haloperidol	C21H23ClFNO2	3559	Moderate		Inter Info	[16], [17]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [87], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283]
D0774		Hydrocortisone (ophthalmic)	C21H30O5	5754	Moderate		Inter Info	[261], [262], [276]
D0778		Hydroxyamphetamine (ophthalmic)	C9H13NO	3651	Moderate		Inter Info	[191], [119], [17]
D0779		Hydroxychloroquine	C18H26ClN3O	3652	Moderate		Inter Info	[26]
D0791		Iloperidone	C24H27FN2O4	71360	Moderate		Inter Info	[16], [17]
D0793		Imatinib	C29H31N7O	5291	Moderate		Inter Info	[422]
D0795		Imipramine	C19H24N2	3696	Moderate		Inter Info	[16], [17]
D0852		Isavuconazonium	C35H35F2N8O5S+	6918606	Moderate		Inter Info	[427]
D0858		Isoniazid	C6H7N3O	3767	Moderate		Inter Info	[16], [301], [302]
D0865		Isradipine	C19H21N3O5	3784	Moderate		Inter Info	[16], [17]
D0866		Istradefylline	C20H24N4O4	5311037	Moderate		Inter Info	[302]
D0873		Ixabepilone	C27H42N2O5S	6445540	Moderate		Inter Info	[428]
D0892		Lansoprazole	C16H14F3N3O2S	3883	Moderate		Inter Info	[16], [17]
D0907		Letrozole	C17H11N5	3902	Moderate		Inter Info	[16], [17]
D0911		Levamlodipine	C20H25ClN2O5	9822750	Moderate		Inter Info	[93], [26], [16], [184], [185]
D0916		Levobupivacaine	C18H28N2O	92253	Moderate		Inter Info	[16], [429]
D0922		Levonorgestrel	C21H28O2	13109	Moderate		Inter Info	[16], [17]
D0950		Loratadine	C22H23ClN2O2	3957	Moderate		Inter Info	[16], [17]
D0955		Loteprednol (ophthalmic)	C21H27ClO5	9865442	Moderate		Inter Info	[261], [262], [276]
D0956		Lovastatin	C24H36O5	53232	Moderate		Inter Info	[194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [38], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [187], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254]
D0966		Macitentan	C19H20Br2N6O4S	16004692	Moderate		Inter Info	[430]
D0979		Maprotiline	C20H23N	4011	Moderate		Inter Info	[16], [17]
D0980		Maraviroc	C29H41F2N5O	3002977	Moderate		Inter Info	[431]
D0987		Meclizine	C25H27ClN2	4034	Moderate		Inter Info	[16], [17]
D0990		Medroxyprogesterone acetate	C24H34O4	6279	Moderate		Inter Info	[191], [119], [17]
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[16], [17]
D0993		Megestrol acetate	C24H32O4	11683	Moderate		Inter Info	[191], [119], [17]
D1010		Mesoridazine	C21H26N2OS2	4078	Moderate		Inter Info	[16], [17]
D1012		Metamfetamine	C10H15N	10836	Moderate		Inter Info	[191], [119], [17]
D1017		Methadone	C21H27NO	4095	Moderate		Inter Info	[432], [433], [434], [435], [436], [437], [438], [439]
D1026		Methotrimeprazine	C19H24N2OS	72287	Moderate		Inter Info	[16], [17]
D1037		Methylergometrine	C20H25N3O2	8226	Moderate		Inter Info	[351], [353], [364]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [87], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283]
D1043		Methysergide	C21H27N3O2	9681	Moderate		Inter Info	[351], [353], [364]
D1046		Metoclopramide	C14H22ClN3O2	4168	Moderate		Inter Info	[16], [17]
D1049		Metoprolol	C15H25NO3	4171	Moderate		Inter Info	[16], [17]
D1054		Mexiletine	C11H17NO	4178	Moderate		Inter Info	[16], [17]
D1060		Midazolam	C18H13ClFN3	4192	Moderate		Inter Info	[16], [17]
D1061		Midodrine	C12H18N2O4	4195	Moderate		Inter Info	[16], [17]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[440], [441]
D1101		Naldemedine	C32H34N4O6	54732242	Moderate		Inter Info	[16], [442]
D1114		Nebivolol	C22H25F2NO4	71301	Moderate		Inter Info	[16], [17]
D1130		Nicardipine	C26H29N3O6	4474	Moderate		Inter Info	[16], [17]
D1134		Nifedipine	C17H18N2O6	4485	Moderate		Inter Info	[16], [17]
D1136		Nilotinib	C28H22F3N7O	644241	Moderate		Inter Info	[446]
D1138		Nimodipine	C21H26N2O7	4497	Moderate		Inter Info	[16], [17]
D1143		Nitisinone	C14H10F3NO5	115355	Moderate		Inter Info	[93], [26], [16]
D1154		Norethisterone	C20H26O2	6230	Moderate		Inter Info	[191], [119], [17]
D1157		Norgestrel	C21H28O2	13109	Moderate		Inter Info	[16], [17]
D1158		Nortriptyline	C19H21N	4543	Moderate		Inter Info	[16], [17]
D1167		Olaparib	C24H23FN4O3	23725625	Moderate		Inter Info	[26], [16], [448]
D1179		Omeprazole	C17H19N3O3S	4594	Moderate		Inter Info	[16], [17]
D1189		Osilodrostat	C13H10FN3	44139752	Moderate		Inter Info	[16], [301], [17]
D1202		Oxybutynin	C22H31NO3	4634	Moderate		Inter Info	[16], [17]
D1212		Paclitaxel	C47H51NO14	36314	Moderate		Inter Info	[449], [450], [26], [451], [452], [453], [454], [373]
D1213		Paclitaxel (protein-bound)	C47H51NO14	36314	Moderate		Inter Info	[449], [450], [26]
D1214		Palbociclib	C24H29N7O2	5330286	Moderate		Inter Info	[16], [455]
D1222		Pantoprazole	C16H15F2N3O4S	4679	Moderate		Inter Info	[16], [17]
D1226		Paricalcitol	C27H44O3	5281104	Moderate		Inter Info	[16], [17]
D1232		Pazopanib	C21H23N7O2S	10113978	Moderate		Inter Info	[456]
D1257		Perphenazine	C21H26ClN3OS	4748	Moderate		Inter Info	[16], [17]
D1299		Pirfenidone	C12H11NO	40632	Moderate		Inter Info	[16], [459], [61]
D1306		Polatuzumab vedotin	NA	NA	Moderate		Inter Info	[460]
D1312		Pomalidomide	C13H11N3O4	134780	Moderate		Inter Info	[16], [17]
D1330		Praziquantel	C19H24N2O2	4891	Moderate		Inter Info	[16], [17]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [87], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283]
D1333		Prednisolone (ophthalmic)	C21H28O5	5755	Moderate		Inter Info	[261], [262], [276]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [87], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283]
D1348		Progesterone	C21H30O2	5994	Moderate		Inter Info	[16], [17]
D1349		Progesterone (topical)	C21H30O2	5994	Moderate		Inter Info	[191], [119], [17]
D1350		Proguanil	C11H16ClN5	6178111	Moderate		Inter Info	[16], [17]
D1352		Promethazine	C17H20N2S	4927	Moderate		Inter Info	[16], [17]
D1353		Propafenone	C21H27NO3	4932	Moderate		Inter Info	[461], [462]
D1357		Propranolol	C16H21NO2	4946	Moderate		Inter Info	[16], [17]
D1361		Protriptyline	C19H21N	4976	Moderate		Inter Info	[16], [17]
D1367		Quazepam	C17H11ClF4N2S	4999	Moderate		Inter Info	[16], [17]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[463], [464], [465], [466], [467], [468], [469], [470], [471]
D1371		Quinidine	C20H24N2O2	441074	Moderate		Inter Info	[16], [17]
D1372		Quinine	C20H24N2O2	3034034	Moderate		Inter Info	[26], [16], [472], [473], [474], [475], [476], [477], [478], [479], [480]
D1373		Rabeprazole	C18H21N3O3S	5029	Moderate		Inter Info	[16], [17]
D1378		Ramelteon	C16H21NO2	208902	Moderate		Inter Info	[16], [17]
D1392		Repaglinide	C27H36N2O4	65981	Moderate		Inter Info	[481], [482], [483], [484], [485], [486], [487]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[26], [488], [16], [489]
D1407		Rimegepant	C28H28F2N6O3	51049968	Moderate		Inter Info	[490]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[16], [17]
D1422		Roflumilast	C17H14Cl2F2N2O3	449193	Moderate		Inter Info	[16], [17]
D1424		Romidepsin	C24H36N4O6S2	5352062	Moderate		Inter Info	[16], [17]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[16], [301], [302]
D1449		Saxagliptin	C18H25N3O2	11243969	Moderate		Inter Info	[16], [491]
D1465		Sildenafil	C22H30N6O4S	135398744	Moderate		Inter Info	[493], [494], [495], [496]
D1473		Simvastatin	C25H38O5	54454	Moderate		Inter Info	[194], [195], [196], [197], [198], [199], [200], [201], [202], [203], [204], [205], [206], [38], [207], [208], [209], [210], [211], [212], [213], [214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [187], [241], [242], [243], [244], [245], [246], [247], [248], [249], [250], [251], [252], [253], [254]
D1476		Sirolimus	C51H79NO13	5284616	Moderate		Inter Info	[26], [16], [497], [498], [499], [187], [500]
D1491		Solifenacin	C23H26N2O2	154059	Moderate		Inter Info	[501]
D1505		Stiripentol	C14H18O3	5311454	Moderate		Inter Info	[16], [301], [17]
D1522		Sunitinib	C22H27FN4O2	5329102	Moderate		Inter Info	[16], [17]
D1526		Tacrolimus	C44H69NO12	445643	Moderate		Inter Info	[26], [16], [497], [498], [499], [187], [500]
D1527		Tadalafil	C22H19N3O4	110635	Moderate		Inter Info	[503]
D1534		Tamsulosin	C20H28N2O5S	129211	Moderate		Inter Info	[504], [505], [506], [61]
D1536		Tasimelteon	C15H19NO2	10220503	Moderate		Inter Info	[507]
D1549		Temsirolimus	C56H87NO16	6918289	Moderate		Inter Info	[509]
D1551		Teniposide	C32H32O13S	452548	Moderate		Inter Info	[16], [17]
D1555		Terfenadine	C32H41NO2	5405	Moderate		Inter Info	[16], [17]
D1559		Testosterone (topical)	C19H28O2	6013	Moderate		Inter Info	[191], [119], [17]
D1560		Tetrabenazine	C19H27NO3	6018	Moderate		Inter Info	[16], [17]
D1581		Ticlopidine	C14H14ClNS	5472	Moderate		Inter Info	[16], [17]
D1585		Timolol	C13H24N4O3S	33624	Moderate		Inter Info	[16], [17]
D1586		Timolol (ophthalmic)	C13H24N4O3S	33624	Moderate		Inter Info	[511], [512], [513]
D1587		Tinidazole	C8H13N3O4S	5479	Moderate		Inter Info	[16], [17]
D1603		Tolbutamide	C12H18N2O3S	5505	Moderate		Inter Info	[16], [17]
D1608		Tolvaptan	C26H25ClN2O3	216237	Moderate		Inter Info	[516]
D1612		Toremifene	C26H28ClNO	3005573	Moderate		Inter Info	[517]
D1616		Tramadol	C16H25NO2	33741	Moderate		Inter Info	[16], [17]
D1624		Trazodone	C19H22ClN5O	5533	Moderate		Inter Info	[16], [17]
D1626		Tretinoin	C20H28O2	444795	Moderate		Inter Info	[16], [17]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[256], [257], [258], [259], [260], [261], [87], [262], [263], [264], [265], [266], [267], [268], [269], [270], [271], [272], [273], [274], [275], [276], [277], [278], [279], [280], [281], [282], [283]
D1630		Triamcinolone (ophthalmic)	C21H27FO6	31307	Moderate		Inter Info	[261], [262], [276]
D1632		Triazolam	C17H12Cl2N4	5556	Moderate		Inter Info	[16], [17]
D1673		Valbenazine	C24H38N2O4	24795069	Moderate		Inter Info	[16], [17]
D1674		Valdecoxib	C16H14N2O3S	119607	Moderate		Inter Info	[16], [17]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[526], [187]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[26], [16], [527]
D1697		Vinblastine	C46H58N4O9	13342	Moderate		Inter Info	[16], [17]
D1698		Vincristine	C46H56N4O10	5978	Moderate		Inter Info	[16], [17]
D1699		Vincristine (liposome)	C46H56N4O10	5978	Moderate		Inter Info	[191], [119], [17]
D1700		Vinorelbine	C45H54N4O8	5311497	Moderate		Inter Info	[16], [17]
D1708		Vortioxetine	C18H22N2S	9966051	Moderate		Inter Info	[16], [17]
D1721		Zileuton	C11H12N2O2S	60490	Moderate		Inter Info	[16], [17]
D1730		Zonisamide	C8H8N2O3S	5734	Moderate		Inter Info	[528], [529]
D0341		Ciprofloxacin	C17H18FN3O3	2764	Minor		Inter Info	[16], [301], [302]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Minor		Inter Info	[530]
D0413		Dalfopristin	C34H50N4O9S	6323289	Minor		Inter Info	[191], [119], [302]
D0426		Darunavir	C27H37N3O7S	213039	Minor		Inter Info	[16], [17]
D0497		Diltiazem	C22H26N2O4S	39186	Minor		Inter Info	[16], [301], [302]
D0516		Donepezil	C24H29NO3	3152	Minor		Inter Info	[531], [61], [532], [533]
D0597		Erythromycin	C37H67NO13	12560	Minor		Inter Info	[16], [301], [302]
D0171		Berotralstat	C30H26F4N6O	137528262	Minor		Inter Info	[16], [301], [302]
D0425		Darolutamide	C19H19ClN6O2	67171867	Minor		Inter Info	[534]
D0696		Fosnetupitant	C31H35F6N4O5P	71544786	Minor		Inter Info	[191], [119], [302]
D0797		Indacaterol	C24H28N2O3	6918554	Minor		Inter Info	[535]
D0906		Letermovir	C29H28F4N4O4	45138674	Minor		Inter Info	[16], [301], [302]
D1074		Mirabegron	C21H24N4O2S	9865528	Minor		Inter Info	[536]
D1127		Netupitant	C30H32F6N4O	6451149	Minor		Inter Info	[191], [119], [302]
D1291		Pimecrolimus (topical)	C43H68ClNO11	6509979	Minor		Inter Info	[537]
D1394		Retapamulin (topical)	C30H47NO4S	6918462	Minor		Inter Info	[538]
D1398		Ribociclib	C23H30N8O	44631912	Minor		Inter Info	[26], [16], [539]
D1428		Ropivacaine	C17H26N2O	175805	Minor		Inter Info	[540], [541], [542], [543], [544], [545], [546]
D1434		Ruxolitinib	C17H18N6	25126798	Minor		Inter Info	[16], [547]
D1690		Verapamil	C27H38N2O4	2520	Minor		Inter Info	[16], [301], [302]
D1726		Ziprasidone	C21H21ClN4OS	60854	Minor		Inter Info	[548], [549], [550], [551]
	CYP450 enzyme induction					Drug Num: 29
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0095		Apalutamide	C21H15F4N5O2S	24872560	Major		Inter Info	[16], [17]
D0194		Bosentan	C27H29N5O6S	104865	Major		Inter Info	[16], [17]
D0255		Carbamazepine	C15H12N2O	2554	Major		Inter Info	[16], [17]
D0300		Cenobamate	C10H10ClN5O2	11962412	Major		Inter Info	[16], [17]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Major		Inter Info	[16], [17]
D0453		Dexamethasone	C22H29FO5	5743	Major		Inter Info	[16], [17]
D0554		Efavirenz	C14H9ClF3NO2	64139	Major		Inter Info	[16], [17]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Major		Inter Info	[16], [17]
D0628		Etravirine	C20H15BrN6O	193962	Major		Inter Info	[16], [17]
D0697		Fosphenytoin	C16H15N2O6P	56339	Major		Inter Info	[16], [17]
D0953		Lorlatinib	C21H19FN6O2	71731823	Major		Inter Info	[16], [17]
D1078		Mitotane	C14H10Cl4	4211	Major		Inter Info	[16], [17]
D1081		Modafinil	C15H15NO2S	4236	Major		Inter Info	[16], [17]
D1099		Nafcillin	C21H22N2O5S	8982	Major		Inter Info	[16], [17]
D1265		Phenobarbital	C12H12N2O3	4763	Major		Inter Info	[16], [17]
D1283		Phenytoin	C15H12N2O2	1775	Major		Inter Info	[16], [17]
D1340		Primidone	C12H14N2O2	4909	Major		Inter Info	[16], [17]
D1399		Rifabutin	C46H62N4O11	135398743	Major		Inter Info	[16], [17]
D1400		Rifampicin	C43H58N4O12	135398735	Major		Inter Info	[119], [120], [17]
D1401		Rifapentine	C47H64N4O12	135403821	Major		Inter Info	[16], [17]
D1502		St. John's Wort	NA	NA	Major		Inter Info	[16], [17]
D0178		Bexarotene	C24H28O2	82146	Moderate		Inter Info	[16], [284], [285]
D1493		Somapacitan	C54H95N13O20S2	129894493	Moderate		Inter Info	[26], [16], [408]
D1128		Nevirapine	C15H14N4O	4463	Moderate		Inter Info	[26], [16], [444], [445]
D1494		Somatotropin	NA	NA	Moderate		Inter Info	[26], [16], [408]
D1495		Somatrem	C43H72N14O14	5487805	Moderate		Inter Info	[26], [16], [502], [408]
D1546		Telotristat ethyl	C27H26ClF3N6O3	25181577	Moderate		Inter Info	[16], [508]
D1615		Trabectedin	C39H43N3O11S	108150	Moderate		Inter Info	[16], [518]
D1652		Troglitazone	C24H27NO5S	5591	Moderate		Inter Info	[519], [520], [521], [522], [523], [524], [525]
Pharmacodynamic additive effects
	Additive myelosuppressive effects					Drug Num: 2
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0370		Clozapine	C18H19ClN4	135398737	Major		Inter Info	[16], [49], [50]
D0433		Deferiprone	C7H9NO2	2972	Major		Inter Info	[26], [54], [55]
	Increased risk of bleeding					Drug Num: 45
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0102		Ardeparin	C26H42N2O37S5	772	Major		Inter Info	[18], [19], [20]
D0104		Argatroban	C23H36N6O5S	92722	Major		Inter Info	[21], [22], [23]
D0176		Betrixaban	C23H22ClN5O3	10275777	Major		Inter Info	[25]
D0189		Bivalirudin	C98H138N24O33	16129704	Major		Inter Info	[21], [22], [23]
D0250		Caplacizumab	NA	NA	Major		Inter Info	[26], [16], [31]
D0414		Dalteparin	C26H42N2O37S5	772	Major		Inter Info	[18], [19], [20]
D0415		Danaparoid	NA	NA	Major		Inter Info	[18], [19], [20]
D0432		Deferasirox	C21H15N3O4	214348	Major		Inter Info	[52], [53]
D0435		Defibrotide	C20H21N4O6P	135565962	Major		Inter Info	[16], [56]
D0447		Desirudin	C287H440N80O110S6	16129703	Major		Inter Info	[21], [22], [23]
D0537		Drotrecogin alfa	NA	NA	Major		Inter Info	[58]
D0551		Edoxaban	C24H30ClN7O4S	10280735	Major		Inter Info	[59]
D0574		Enoxaparin	C26H42N2O37S5	772	Major		Inter Info	[18], [19], [20]
D0805		Inotersen	C230H318N69O121P19S19	121492004	Major		Inter Info	[16], [52], [69]
D0690		Fondaparinux	C31H53N3O49S8	5282448	Major		Inter Info	[18], [19], [20]
D0784		Ibritumomab tiuxetan	NA	NA	Major		Inter Info	[85]
D0785		Ibrutinib	C25H24N6O2	24821094	Major		Inter Info	[86]
D0904		Lepirudin	C287H440N80O111S6	118856773	Major		Inter Info	[21], [22], [23]
D1174		Omacetaxine mepesuccinate	C29H39NO9	285033	Major		Inter Info	[52], [105]
D1221		Panobinostat	C21H23N3O2	6918837	Major		Inter Info	[26], [16], [107]
D1313		Ponatinib	C29H27F3N6O	24826799	Major		Inter Info	[114]
D1328		Prasugrel	C20H20FNO3S	6918456	Major		Inter Info	[16], [115]
D1380		Ramucirumab	NA	NA	Major		Inter Info	[116]
D1387		Regorafenib	C21H15ClF4N4O3	11167602	Major		Inter Info	[16], [87], [118]
D1417		Rivaroxaban	C19H18ClN3O5S	9875401	Major		Inter Info	[121]
D1588		Tinzaparin	C26H42N2O37S5	772	Major		Inter Info	[18], [19], [20]
D1592		Tipranavir	C31H33F3N2O5S	54682461	Major		Inter Info	[172]
D1613		Tositumomab	NA	NA	Major		Inter Info	[173], [174]
D1614		Tositumomab (I-131)	NA	NA	Major		Inter Info	[173], [174]
D1705		Vorapaxar	C29H33FN2O4	10077130	Major		Inter Info	[176]
D1769		Deoxycholic acid	C24H40O4	222528	Moderate		Inter Info	[52], [339]
D0451		Desvenlafaxine	C16H25NO2	125017	Moderate		Inter Info	[340], [341], [342]
D0752		Hemin	C34H32FeN4O4	26945	Moderate		Inter Info	[416]
D1815		Icosapent	C20H30O2	446284	Moderate		Inter Info	[16], [417], [418]
D0792		Iloprost	C22H32O4	5311181	Moderate		Inter Info	[419], [420], [421]
D0920		Levomilnacipran	C15H22N2O	6917779	Moderate		Inter Info	[340], [341], [342]
D1139		Nintedanib	C31H33N5O4	135423438	Moderate		Inter Info	[447]
D1178		Omega-3 fatty acids	C60H92O6	56842239	Moderate		Inter Info	[16], [417], [418]
D1229		Paroxetine	C19H20FNO3	43815	Moderate		Inter Info	[340], [341], [342]
D1249		Pentosan polysulfate	C10H18O21S4	37720	Moderate		Inter Info	[52], [457]
D1251		Pentoxifylline	C13H18N4O3	4740	Moderate		Inter Info	[93], [458]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[340], [341], [342]
D1464		Sibutramine	C17H26ClN	5210	Moderate		Inter Info	[492]
D1579		Ticagrelor	C23H28F2N6O4S	9871419	Moderate		Inter Info	[16], [510]
D1625		Treprostinil	C23H34O5	6918140	Moderate		Inter Info	[419], [420], [421]
	Increased risk of hepatotoxicity					Drug Num: 13
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1258		Pexidartinib	C20H15ClF3N5	25151352	Major		Inter Info	[16], [17]
D0900		Leflunomide	C12H9F3N2O2	3899	Major		Inter Info	[93], [94], [95]
D1073		Mipomersen	C230H324N67O122P19S19	118984467	Major		Inter Info	[101]
D1556		Teriflunomide	C12H9F3N2O2	54684141	Major		Inter Info	[93], [94], [95]
D0248		Cannabidiol	C21H30O2	644019	Moderate		Inter Info	[16], [298]
D0357		Clofarabine	C10H11ClFN5O3	119182	Moderate		Inter Info	[304]
D0584		Epirubicin	C27H29NO11	41867	Moderate		Inter Info	[26], [16], [382]
D1389		Remdesivir	C27H35N6O8P	121304016	Moderate		Inter Info	[26], [16], [404], [405], [406]
D0826		Interferon beta-1a	NA	NA	Moderate		Inter Info	[423], [424], [425], [426]
D0827		Interferon beta-1b	NA	NA	Moderate		Inter Info	[423], [424], [425], [426]
D1106		Naltrexone	C20H23NO4	5360515	Moderate		Inter Info	[443]
D1239		Peginterferon beta-1a	NA	NA	Moderate		Inter Info	[423], [424], [425], [426]
D1589		Tioguanine	C5H5N5S	2723601	Moderate		Inter Info	[514], [515]

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362	Product Information. Migranal (dihydroergotamine nasal). Novartis Pharmaceuticals, East Hanover, NJ.
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409	Product Information. Ubrelvy (ubrogepant). Allergan Inc, Irvine, CA.
410	Product Information. Rinvoq (upadacitinib). AbbVie US LLC, North Chicago, IL.
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442	Product Information. Symproic (naldemedine). Shionogi USA Inc, Florham Park, NJ.
443	Product Information. ReVia (naltrexone). DuPont Pharmaceuticals, Wilmington, DE.
444	Product Information. Viramune (nevirapine). Boehringer-Ingelheim, Ridgefield, CT.
445	Product Information. Viramune XR (nevirapine). Boehringer Ingelheim, Ridgefield, CT.
446	Product Information. Tasigna (nilotinib). Novartis Pharmaceuticals, East Hanover, NJ.
447	Product Information. Ofev (nintedanib). Boehringer Ingelheim, Ridgefield, CT.
448	Product Information. Lynparza (olaparib). Astra-Zeneca Pharmaceuticals, Wilmington, DE.
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