Details of Drug

Drug General Information (ID: D0500)
Drug Name	Dimethyl sulfoxide
Drug Type	Small molecule
Drug Synonymous	Rimso-50 Click to Show/Hide
Disease Class	FA20: Rheumatoid arthritis
Therapeutic Class	Genitourinary Tract Agents
Structure
Structure	3D Structure		2D Structure
Formula	C2H6OS
InChI	1S/C2H6OS/c1-4(2)3/h1-2H3
InChIKey	IAZDPXIOMUYVGZ-UHFFFAOYSA-N
Canonical SMILES	CS(=O)C
External Link
	Pubchem ID	679
	CAS Number	67-68-5
	CHEBI ID	28262
	TTD ID	D08HVE
	VARIDT ID	DR01178

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM004 Affected intra/extra-hepatic metabolism AM006 Pharmacodynamic additive effects BM018 Non-CYP450 enzyme inhibition BM074 Increased risk of peripheral neuropathy
Relation Graph

Full list of drugs interacting with Dimethyl sulfoxide
Affected intra/extra-hepatic metabolism
	Non-CYP450 enzyme inhibition					Drug Num: 1
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D1520		Sulindac	C20H17FO3S	1548887	Moderate		Inter Info	[1], [2], [3], [4], [5]
Pharmacodynamic additive effects

References
1	Cerner Multum, Inc. "Australian Product Information.".
2	Product Information. Clinoril (sulindac). Merck & Co, Inc, West Point, PA.
3	Reinstein L, Mahon R, Russso GL "Peripheral neuropathy after concomitant dimethyl sulfoxide use and sulindac therapy." Arch Phys Med Rehabil 63 (1982): 581-4. [PMID: 6291491]
4	Swanson BN, Boppana Vk, Vlasses PH, Rotmensch HH, Ferguson RK "Dimethyl sulfoxide inhibits bioactivation of sulindac." J Lab Clin Med 102 (1983): 95-101. [PMID: 6854139]
5	Swanson BN, Ferguson RK, Raskin NH, Wolf BA "Peripheral neuropathy after concomitant administration of dimethyl sulfoxide and sulindac." Arthritis Rheum 26 (1983): 791-3. [PMID: 6305373]