Drug General Information (ID: D0457)
  Drug Name
Dexfenfluramine
  Drug Type Small molecule
  Drug Synonymous
DEXFENFLURAN; Dexfenfluramine (INN); Redux (TN); (2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine; (S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine
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  Disease Class 5B80-5B81: Obesity
  Therapeutic Class Appetite Depressants
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C12H16F3N
  InChI 1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
  InChIKey DBGIVFWFUFKIQN-VIFPVBQESA-N
  Canonical SMILES CCNC(C)CC1=CC(=CC=C1)C(F)(F)F
  External Link
Pubchem ID 66265
CAS Number 3239-44-9
CHEBI ID 439329
TTD ID D0F9SG
INTEDE ID DR0466

Drug-Drug Interaction Network
  Sunburst Graph
AM003  Affected organization distribution
AM004  Affected intra/extra-hepatic metabolism
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM014  Interference of cell/tissue uptake
BM017  CYP450 enzyme inhibition
BM038  Additive CNS depression effects
BM041  Additive hypertensive effects
BM046  Additive serotonergic effects
BM050  Increased risk of bleeding
BM064  Increased risk of hypoglycemia
BM069  Increased risk of lowers seizure threshold
BM098  Antagonize the effect of serotonergic agents
BM109  Increased risk of other adverse reactions (Unspecific)
  Relation Graph
 Full list of drugs interacting with Dexfenfluramine
      Affected organization distribution
   Interference of cell/tissue uptake Drug Num:  2
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0829
 
Iobenguane (I-131)
 
C8H10IN3
 
60860 
Major    Inter Info   
[124]
D1821
 
Iobenguane (I-123)
 
C8H10IN3
 
60860 
Moderate    Inter Info   
[23], [167], [319]
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  32
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0220
 
Bupropion
 
C13H18ClNO
 
444 
Major    Inter Info   
[105], [106], [107], [108], [109], [110], [111], [112], [113], [114], [115], [116], [117], [118], [119], [120], [121], [122], [123]
D1533
 
Tamoxifen
 
C26H29NO
 
2733526 
Major    Inter Info   
[214], [215], [216], [217], [218], [219], [220], [221], [222], [223], [224], [225], [226], [227], [228], [229], [230], [231], [232], [233], [234], [235], [236], [237], [238], [239], [240], [241], [242], [243], [244], [245], [246], [247], [248]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Major    Inter Info   
[249], [250], [251]
D0119
 
Atomoxetine
 
C17H21NO
 
54841 
Moderate    Inter Info   
[268], [269], [270]
D0298
 
Celecoxib
 
C17H14F3N3O2S
 
2662 
Moderate    Inter Info   
[283]
D0308
 
Cevimeline
 
C10H17NOS
 
83898 
Moderate    Inter Info   
[284]
D0338
 
Cinacalcet
 
C22H22F3N
 
156419 
Moderate    Inter Info   
[180], [285], [286]
D0356
 
Clobazam
 
C16H13ClN2O2
 
2789 
Moderate    Inter Info   
[287], [288]
D0379
 
Codeine
 
C18H21NO3
 
5284371 
Moderate    Inter Info   
[289], [290], [291], [292], [293], [294], [240], [295], [296], [297], [298], [299], [300]
D0424
 
Darifenacin
 
C28H30N2O2
 
444031 
Moderate    Inter Info   
[302]
D0007
 
Abiraterone
 
C24H31NO
 
132971 
Moderate    Inter Info   
[303]
D0105
 
Aripiprazole
 
C23H27Cl2N3O2
 
60795 
Moderate    Inter Info   
[304]
D0375
 
Cobicistat
 
C40H53N7O5S2
 
25151504 
Moderate    Inter Info   
[305]
D0409
 
Dacomitinib
 
C24H25ClFN5O2
 
11511120 
Moderate    Inter Info   
[306]
D0534
 
Dronedarone
 
C31H44N2O5S
 
208898 
Moderate    Inter Info   
[307]
D0559
 
Eliglustat
 
C23H36N2O4
 
23652731 
Moderate    Inter Info   
[180], [171], [308]
D0638
 
Fedratinib
 
C27H36N6O3S
 
16722836 
Moderate    Inter Info   
[171], [309]
D0655
 
Fesoterodine
 
C26H37NO3
 
6918558 
Moderate    Inter Info   
[310]
D0724
 
Givosiran
 
C78H139N11O30
 
119058042 
Moderate    Inter Info   
[318]
D1074
 
Mirabegron
 
C21H24N4O2S
 
9865528 
Moderate    Inter Info   
[320]
D1136
 
Nilotinib
 
C28H22F3N7O
 
644241 
Moderate    Inter Info   
[321]
D1302
 
Pitolisant
 
C17H26ClNO
 
9948102 
Moderate    Inter Info   
[171], [240], [328]
D1423
 
Rolapitant
 
C25H26F6N2O2
 
10311306 
Moderate    Inter Info   
[240]
D1687
 
Vemurafenib
 
C23H18ClF2N3O3S
 
42611257 
Moderate    Inter Info   
[329]
D0793
 
Imatinib
 
C29H31N7O
 
5291 
Moderate    Inter Info   
[331]
D1383
 
Ranolazine
 
C24H33N3O4
 
56959 
Moderate    Inter Info   
[335]
D1415
 
Ritonavir
 
C37H48N6O5S2
 
392622 
Moderate    Inter Info   
[336]
D1534
 
Tamsulosin
 
C20H28N2O5S
 
129211 
Moderate    Inter Info   
[337], [338], [339], [240]
D1553
 
Terbinafine
 
C21H25N
 
1549008 
Moderate    Inter Info   
[340], [341], [342], [343]
D1586
 
Timolol (ophthalmic)
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[344], [345], [346]
D0516
 
Donepezil
 
C24H29NO3
 
3152 
Minor    Inter Info   
[347], [240], [348], [349]
D1607
 
Tolterodine
 
C22H31NO
 
443879 
Minor    Inter Info   
[350], [351], [240]
      Pharmacodynamic additive effects
   Additive CNS depression effects Drug Num:  14
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0219
 
Buprenorphine
 
C29H41NO4
 
644073 
Moderate    Inter Info   
[271], [260], [272], [273], [262], [45], [46], [14], [264], [255], [257], [32], [253], [28], [16], [2], [56], [263], [82], [258], [96], [274], [50], [275], [143], [8], [85], [276], [254], [277], [91], [84], [278], [279], [280], [256], [30], [281], [259], [282]
D0226
 
Butorphanol
 
C21H29NO2
 
5361092 
Moderate    Inter Info   
[271], [260], [272], [273], [262], [45], [46], [14], [264], [255], [257], [32], [253], [28], [16], [2], [56], [263], [82], [258], [96], [274], [50], [275], [143], [8], [85], [276], [254], [277], [91], [84], [278], [279], [280], [256], [30], [281], [259], [282]
D0161
 
Benzhydrocodone
 
C25H25NO4
 
49836084 
Moderate    Inter Info   
[271], [260], [272]
D0493
 
Dihydrocodeine
 
C18H23NO3
 
5284543 
Moderate    Inter Info   
[271], [260], [272]
D1169
 
Oliceridine
 
C22H30N2O2S
 
66553195 
Moderate    Inter Info   
[271], [260], [272]
D1208
 
Oxymorphone
 
C17H19NO4
 
5284604 
Moderate    Inter Info   
[271], [260], [272], [273], [262], [45], [46], [14], [264], [255], [257], [32], [253], [28], [16], [2], [56], [263], [82], [258], [96], [274], [50], [275], [143], [8], [85], [276], [254], [277], [91], [84], [278], [279], [280], [256], [30], [281], [259], [282]
D0617
 
Ethanol
 
C2H6O
 
702 
Moderate    Inter Info   
[267], [330], [265]
D0772
 
Hydrocodone
 
C18H21NO3
 
5284569 
Moderate    Inter Info   
[271], [262], [263], [272], [85], [260], [46], [279], [14], [28], [280], [45], [56], [82], [274], [264], [30], [256], [50], [143], [253], [257], [16], [281], [96], [258], [276], [84], [259], [275], [282], [278], [273], [255], [32], [2], [8], [254], [277], [91]
D0776
 
Hydromorphone
 
C17H19NO3
 
5284570 
Moderate    Inter Info   
[271], [262], [263], [272], [85], [260], [46], [279], [14], [28], [280], [45], [56], [82], [274], [264], [30], [256], [50], [143], [253], [257], [16], [281], [96], [258], [276], [84], [259], [275], [282], [278], [273], [255], [32], [2], [8], [254], [277], [91]
D0923
 
Levorphanol
 
C17H23NO
 
5359272 
Moderate    Inter Info   
[271], [260], [272], [273], [262], [45], [46], [14], [264], [255], [257], [32], [253], [28], [16], [2], [56], [263], [82], [258], [96], [274], [50], [275], [143], [8], [85], [276], [254], [277], [91], [84], [278], [279], [280], [256], [30], [281], [259], [282]
D1017
 
Methadone
 
C21H27NO
 
4095 
Moderate    Inter Info   
[271], [262], [263], [272], [85], [260], [46], [279], [14], [28], [280], [45], [56], [82], [274], [264], [30], [256], [50], [143], [253], [257], [16], [281], [96], [258], [276], [84], [259], [275], [282], [278], [273], [255], [32], [2], [8], [254], [277], [91]
D1089
 
Morphine
 
C17H19NO3
 
5288826 
Moderate    Inter Info   
[271], [260], [272], [273], [262], [45], [46], [14], [264], [255], [257], [32], [253], [28], [16], [2], [56], [263], [82], [258], [96], [274], [50], [275], [143], [8], [85], [276], [254], [277], [91], [84], [278], [279], [280], [256], [30], [281], [259], [282]
D1100
 
Nalbuphine
 
C21H27NO4
 
5311304 
Moderate    Inter Info   
[271], [260], [272], [273], [262], [45], [46], [14], [264], [255], [257], [32], [253], [28], [16], [2], [56], [263], [82], [258], [96], [274], [50], [275], [143], [8], [85], [276], [254], [277], [91], [84], [278], [279], [280], [256], [30], [281], [259], [282]
D1203
 
Oxycodone
 
C18H21NO4
 
5284603 
Moderate    Inter Info   
[271], [260], [272], [273], [262], [45], [46], [14], [264], [255], [257], [32], [253], [28], [16], [2], [56], [263], [82], [258], [96], [274], [50], [275], [143], [8], [85], [276], [254], [277], [91], [84], [278], [279], [280], [256], [30], [281], [259], [282]
   Additive hypertensive effects Drug Num:  4
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0074
 
Amphetamine
 
C9H13N
 
3007 
Major    Inter Info   
[100], [101], [102]
D0465
 
Dextroamphetamine
 
C9H13N
 
5826 
Major    Inter Info   
[100], [101], [102]
D0937
 
Lisdexamfetamine
 
C15H25N3O
 
11597698 
Major    Inter Info   
[100], [101], [102]
D1464
 
Sibutramine
 
C17H26ClN
 
5210 
Major    Inter Info   
[100], [101], [102]
   Additive serotonergic effects Drug Num:  63
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0035
 
Alfentanil
 
C21H32N6O3
 
51263 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0041
 
Almotriptan
 
C17H25N3O2S
 
123606 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0068
 
Amitriptyline
 
C20H23N
 
2160 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0072
 
Amoxapine
 
C17H16ClN3O
 
2170 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0222
 
Buspirone
 
C21H31N5O2
 
2477 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0398
 
Cyclobenzaprine
 
C20H21N
 
2895 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0446
 
Desipramine
 
C18H22N2
 
2995 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0361
 
Clomipramine
 
C19H23ClN2
 
2801 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0451
 
Desvenlafaxine
 
C16H25NO2
 
125017 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0853
 
Isocarboxazid
 
C12H13N3O2
 
3759 
Major    Inter Info   
[130], [131], [132], [133], [134], [135], [136], [137], [8], [11], [138], [139], [140], [141], [142], [17], [19], [143], [144], [145], [146], [147], [148], [149], [150], [151], [45], [47], [49], [50], [54], [152], [153], [154], [62], [63], [64], [65], [155], [75], [77], [78], [156], [157], [158], [159], [160], [161], [91], [162], [163], [164], [165], [166]
D0897
 
Lasmiditan
 
C19H18F3N3O2
 
11610526 
Major    Inter Info   
[167], [168], [169]
D0920
 
Levomilnacipran
 
C15H22N2O
 
6917779 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0940
 
Lithium carbonate
 
CLi2O3
 
11125 
Major    Inter Info   
[170], [9], [50]
D1036
 
Methylene blue
 
C16H18ClN3S
 
6099 
Major    Inter Info   
[7], [171], [172], [173], [174], [175], [176], [177], [178], [179]
D1066
 
Milnacipran
 
C15H22N2O
 
65833 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [180], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1385
 
Rasagiline
 
C12H13N
 
3052776 
Major    Inter Info   
[130], [131], [132], [133], [134], [135], [136], [137], [8], [11], [138], [139], [140], [141], [142], [17], [19], [143], [144], [145], [146], [147], [148], [149], [150], [151], [45], [47], [49], [50], [54], [152], [153], [154], [62], [63], [64], [65], [155], [75], [77], [78], [156], [157], [158], [159], [160], [161], [91], [162], [163], [164], [165], [166]
D1437
 
Safinamide
 
C17H19FN2O2
 
131682 
Major    Inter Info   
[130], [131], [132], [133], [134], [135], [136], [137], [8], [11], [138], [139], [140], [141], [142], [17], [19], [143], [144], [145], [146], [147], [148], [149], [150], [151], [45], [47], [49], [50], [54], [152], [153], [154], [62], [63], [64], [65], [155], [75], [77], [78], [156], [157], [158], [159], [160], [161], [91], [162], [163], [164], [165], [166]
D1502
 
St. John's Wort
 
NA
 
NA
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1535
 
Tapentadol
 
C14H23NO
 
9838022 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1696
 
Vilazodone
 
C26H27N5O2
 
6918314 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1708
 
Vortioxetine
 
C18H22N2S
 
9966051 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0466
 
Dextromethorphan
 
C18H25NO
 
5360696 
Major    Inter Info   
[1], [2], [4], [5], [6], [8], [9], [10], [11], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [31], [32], [33], [34], [35], [37], [38], [39], [40], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [67], [68], [69], [70], [71], [72], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0494
 
Dihydroergotamine
 
C33H37N5O5
 
10531 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0514
 
Dolasetron
 
C19H20N2O3
 
3033818 
Major    Inter Info   
[105], [180], [171], [206], [207], [208], [209]
D0525
 
Doxepin
 
C19H21NO
 
667477 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0526
 
Doxepin (topical)
 
C19H21NO
 
667477 
Major    Inter Info   
[10], [58], [60]
D0539
 
Duloxetine
 
C18H19NOS
 
60835 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0557
 
Eletriptan
 
C22H26N2O2S
 
77993 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0593
 
Ergotamine
 
C33H35N5O5
 
8223 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0646
 
Fentanyl
 
C22H28N2O
 
3345 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0702
 
Frovatriptan
 
C14H17N3O
 
77992 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0738
 
Granisetron
 
C18H24N4O
 
5284566 
Major    Inter Info   
[105], [180], [171], [206], [207], [208], [209]
D0795
 
Imipramine
 
C19H24N2
 
3696 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D0933
 
Linezolid
 
C16H20FN3O4
 
441401 
Major    Inter Info   
[4], [5], [7], [171], [210], [13], [22], [211], [26], [27], [35], [40], [212], [45], [50], [51], [52], [213], [54], [57], [81], [87], [90], [91], [92], [93], [95], [99], [178]
D0979
 
Maprotiline
 
C20H23N
 
4011 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1001
 
Meperidine
 
C15H21NO2
 
4058 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1075
 
Mirtazapine
 
C17H19N3
 
4205 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1110
 
Naratriptan
 
C17H25N3O2S
 
4440 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1158
 
Nortriptyline
 
C19H21N
 
4543 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1181
 
Ondansetron
 
C18H19N3O
 
4595 
Major    Inter Info   
[105], [180], [171], [206], [207], [208], [209]
D1216
 
Palonosetron
 
C19H24N2O
 
6337614 
Major    Inter Info   
[105], [180], [171], [206], [207], [208], [209]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1247
 
Pentazocine
 
C19H27NO
 
441278 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1263
 
Phenelzine
 
C8H12N2
 
3675 
Major    Inter Info   
[130], [131], [132], [133], [134], [135], [136], [137], [8], [11], [138], [139], [140], [141], [142], [17], [19], [143], [144], [145], [146], [147], [148], [149], [150], [151], [45], [47], [49], [50], [54], [152], [153], [154], [62], [63], [64], [65], [155], [75], [77], [78], [156], [157], [158], [159], [160], [161], [91], [162], [163], [164], [165], [166]
D1345
 
Procarbazine
 
C12H19N3O
 
4915 
Major    Inter Info   
[130], [131], [132], [133], [134], [135], [136], [137], [8], [11], [138], [139], [140], [141], [142], [17], [19], [143], [144], [145], [146], [147], [148], [149], [150], [151], [45], [47], [49], [50], [54], [152], [153], [154], [62], [63], [64], [65], [155], [75], [77], [78], [156], [157], [158], [159], [160], [161], [91], [162], [163], [164], [165], [166]
D1361
 
Protriptyline
 
C19H21N
 
4976 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1390
 
Remifentanil
 
C20H28N2O5
 
60815 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1419
 
Rizatriptan
 
C15H19N5
 
5078 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1455
 
Selegiline
 
C13H17N
 
26757 
Major    Inter Info   
[130], [131], [132], [133], [134], [135], [136], [137], [8], [11], [138], [139], [140], [141], [142], [17], [19], [143], [144], [145], [146], [147], [148], [149], [150], [151], [45], [47], [49], [50], [54], [152], [153], [154], [62], [63], [64], [65], [155], [75], [77], [78], [156], [157], [158], [159], [160], [161], [91], [162], [163], [164], [165], [166]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1512
 
Sufentanil
 
C22H30N2O2S
 
41693 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1521
 
Sumatriptan
 
C14H21N3O2S
 
5358 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1620
 
Tranylcypromine
 
C9H11N
 
19493 
Major    Inter Info   
[144], [150], [151]
D1624
 
Trazodone
 
C19H22ClN5O
 
5533 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1647
 
Trimipramine
 
C20H26N2
 
5584 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1689
 
Venlafaxine
 
C17H27NO2
 
5656 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1728
 
Zolmitriptan
 
C16H21N3O2
 
60857 
Major    Inter Info   
[1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17], [18], [19], [20], [21], [22], [23], [24], [25], [26], [27], [28], [29], [30], [31], [32], [33], [34], [35], [36], [37], [38], [39], [40], [41], [42], [43], [44], [45], [46], [47], [48], [49], [50], [51], [52], [53], [54], [55], [56], [57], [58], [59], [60], [61], [62], [63], [64], [65], [66], [67], [68], [69], [70], [71], [72], [73], [74], [75], [76], [77], [78], [79], [80], [81], [82], [83], [84], [85], [86], [87], [88], [89], [90], [91], [92], [93], [94], [95], [96], [97], [98], [99]
D1211
 
Ozanimod
 
C23H24N4O3
 
52938427 
Moderate    Inter Info   
[130], [131], [132], [133], [134], [135], [136], [137], [8], [9], [10], [11], [138], [139], [140], [141], [142], [17], [322], [19], [143], [144], [145], [146], [147], [148], [149], [323], [150], [151], [45], [47], [49], [50], [54], [58], [152], [153], [154], [60], [61], [62], [63], [64], [65], [67], [68], [69], [155], [70], [74], [75], [76], [77], [78], [324], [79], [80], [156], [86], [157], [158], [159], [160], [161], [91], [325], [162], [163], [164], [165], [166]
   Increased risk of bleeding Drug Num:  72
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1221
 
Panobinostat
 
C21H23N3O2
 
6918837 
Major    Inter Info   
[181], [182], [183], [184], [180], [171], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [199], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0005
 
Abciximab
 
NA
 
NA
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0047
 
Alteplase
 
NA
 
NA
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0084
 
Anagrelide
 
C10H7Cl2N3O
 
135409400 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0104
 
Argatroban
 
C23H36N6O5S
 
92722 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0189
 
Bivalirudin
 
C98H138N24O33
 
16129704 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0336
 
Cilostazol
 
C20H27N5O2
 
2754 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0364
 
Clopidogrel
 
C16H16ClNO2S
 
60606 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0092
 
Antithrombin Alfa
 
NA
 
NA
Moderate    Inter Info   
[184], [200], [201]
D0093
 
Antithrombin III human
 
NA
 
NA
Moderate    Inter Info   
[184], [200], [201]
D0096
 
Apixaban
 
C25H25N5O4
 
10182969 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0129
 
Avapritinib
 
C26H27FN10
 
118023034 
Moderate    Inter Info   
[184], [200], [201]
D0176
 
Betrixaban
 
C23H22ClN5O3
 
10275777 
Moderate    Inter Info   
[184], [200], [201]
D0187
 
Bismuth subsalicylate
 
C7H6BiO4
 
16682734 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0230
 
Cabozantinib
 
C28H24FN3O5
 
25102847 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0247
 
Cangrelor
 
C17H25Cl2F3N5O12P3S2
 
9854012 
Moderate    Inter Info   
[184], [200], [201]
D0250
 
Caplacizumab
 
NA
 
NA
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0331
 
Choline salicylate
 
C12H19NO4
 
54686350 
Moderate    Inter Info   
[184], [200], [201]
D0414
 
Dalteparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[181], [182], [183], [189], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [79], [200], [201], [203], [204]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0435
 
Defibrotide
 
C20H21N4O6P
 
135565962 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0447
 
Desirudin
 
C287H440N80O110S6
 
16129703 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0551
 
Edoxaban
 
C24H30ClN7O4S
 
10280735 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0574
 
Enoxaparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[181], [182], [183], [189], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [79], [200], [201], [203], [204]
D0586
 
Epoprostenol
 
C20H32O5
 
5282411 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0785
 
Ibrutinib
 
C25H24N6O2
 
24821094 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0805
 
Inotersen
 
C230H318N69O121P19S19
 
121492004 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1313
 
Ponatinib
 
C29H27F3N6O
 
24826799 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1328
 
Prasugrel
 
C20H20FNO3S
 
6918456 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1380
 
Ramucirumab
 
NA
 
NA
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1387
 
Regorafenib
 
C21H15ClF4N4O3
 
11167602 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1417
 
Rivaroxaban
 
C19H18ClN3O5S
 
9875401 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1434
 
Ruxolitinib
 
C17H18N6
 
25126798 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1538
 
Tazemetostat
 
C34H44N4O4
 
66558664 
Moderate    Inter Info   
[184], [200], [201]
D1579
 
Ticagrelor
 
C23H28F2N6O4S
 
9871419 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1623
 
Trastuzumab emtansine
 
NA
 
NA
Moderate    Inter Info   
[184], [200], [201]
D1705
 
Vorapaxar
 
C29H33FN2O4
 
10077130 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1718
 
Zanubrutinib
 
C27H29N5O3
 
135565884 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0476
 
Diclofenac
 
C14H11Cl2NO2
 
3033 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0489
 
Diflunisal
 
C13H8F2O3
 
3059 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0506
 
Dipyridamole
 
C24H40N8O4
 
3108 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0537
 
Drotrecogin alfa
 
NA
 
NA
Moderate    Inter Info   
[184], [200], [201]
D0588
 
Eptifibatide
 
C35H49N11O9S2
 
448812 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0624
 
Etodolac
 
C17H21NO3
 
3308 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0645
 
Fenoprofen
 
C15H14O3
 
3342 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0680
 
Flurbiprofen
 
C15H13FO2
 
3394 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0690
 
Fondaparinux
 
C31H53N3O49S8
 
5282448 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0753
 
Heparin
 
C26H42N2O37S5
 
772 
Moderate    Inter Info   
[181], [182], [183], [189], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [79], [200], [201], [203], [204]
D0784
 
Ibritumomab tiuxetan
 
NA
 
NA
Moderate    Inter Info   
[184], [200], [201]
D0786
 
Ibuprofen
 
C13H18O2
 
3672 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0792
 
Iloprost
 
C22H32O4
 
5311181 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0800
 
Indomethacin
 
C19H16ClNO4
 
3715 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0881
 
Ketoprofen
 
C16H14O3
 
3825 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0882
 
Ketorolac
 
C15H13NO3
 
3826 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0904
 
Lepirudin
 
C287H440N80O111S6
 
118856773 
Moderate    Inter Info   
[184], [200], [201]
D0988
 
Meclofenamic acid
 
C14H11Cl2NO2
 
4037 
Moderate    Inter Info   
[184], [200], [201]
D0991
 
Mefenamic acid
 
C15H15NO2
 
4044 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D0995
 
Meloxicam
 
C14H13N3O4S2
 
54677470 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1097
 
Nabumetone
 
C15H16O2
 
4409 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1109
 
Naproxen
 
C14H14O3
 
156391 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1196
 
Oxaprozin
 
C18H15NO3
 
4614 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1300
 
Piroxicam
 
C15H13N3O4S
 
54676228 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1395
 
Reteplase
 
NA
 
NA
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1520
 
Sulindac
 
C20H17FO3S
 
1548887 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1550
 
Tenecteplase
 
NA
 
NA
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1581
 
Ticlopidine
 
C14H14ClNS
 
5472 
Moderate    Inter Info   
[184], [200], [201]
D1593
 
Tirofiban
 
C22H36N2O5S
 
60947 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1606
 
Tolmetin
 
C15H15NO3
 
5509 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1614
 
Tositumomab (I-131)
 
NA
 
NA
Moderate    Inter Info   
[184], [200], [201]
D1625
 
Treprostinil
 
C23H34O5
 
6918140 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
D1711
 
Warfarin
 
C19H16O4
 
54678486 
Moderate    Inter Info   
[181], [182], [183], [184], [180], [9], [185], [186], [187], [188], [189], [190], [191], [192], [193], [194], [195], [196], [197], [198], [60], [61], [62], [64], [65], [68], [69], [74], [75], [76], [77], [78], [79], [200], [201], [202], [203], [204], [205]
   Increased risk of hypoglycemia Drug Num:  34
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0009
 
Acarbose
 
C25H43NO18
 
41774 
Moderate    Inter Info   
[265], [266], [267]
D0325
 
Chlorpropamide
 
C10H13ClN2O3S
 
2727 
Moderate    Inter Info   
[265], [266], [267]
D0029
 
Albiglutide
 
C148H224N40O45
 
145994868 
Moderate    Inter Info   
[265], [266], [267]
D0042
 
Alogliptin
 
C18H21N5O2
 
11450633 
Moderate    Inter Info   
[265], [266], [267]
D0245
 
Canagliflozin
 
C24H25FO5S
 
24812758 
Moderate    Inter Info   
[265], [266], [267]
D0565
 
Empagliflozin
 
C23H27ClO7
 
11949646 
Moderate    Inter Info   
[265], [266], [267]
D0808
 
Insulin aspart (aspart)
 
C256H381N65O79S6
 
118984445 
Moderate    Inter Info   
[265], [266], [267]
D0809
 
Insulin degludec
 
C274H411N65O81S6
 
118984462 
Moderate    Inter Info   
[265], [266], [267]
D0810
 
Insulin detemir
 
C267H402N64O76S6
 
16137271 
Moderate    Inter Info   
[265], [266], [267]
D0812
 
Insulin glulisine
 
C258H384N64O78S6
 
16136701 
Moderate    Inter Info   
[265], [266], [267]
D0930
 
Linagliptin
 
C25H28N8O2
 
10096344 
Moderate    Inter Info   
[265], [266], [267]
D0936
 
Liraglutide
 
C172H265N43O51
 
16134956 
Moderate    Inter Info   
[265], [266], [267]
D0941
 
Lixisenatide
 
C215H347N61O65S
 
90472060 
Moderate    Inter Info   
[265], [266], [267]
D1326
 
Pramlintide
 
C171H267N51O53S2
 
70691388 
Moderate    Inter Info   
[265], [266], [267]
D1449
 
Saxagliptin
 
C18H25N3O2
 
11243969 
Moderate    Inter Info   
[265], [266], [267]
D1477
 
Sitagliptin
 
C16H15F6N5O
 
4369359 
Moderate    Inter Info   
[265], [266], [267]
D0727
 
Glimepiride
 
C24H34N4O5S
 
3476 
Moderate    Inter Info   
[265], [266], [267]
D0728
 
Glipizide
 
C21H27N5O4S
 
3478 
Moderate    Inter Info   
[265], [266], [267]
D0730
 
Glyburide
 
C23H28ClN3O5S
 
3488 
Moderate    Inter Info   
[265], [266], [267]
D0811
 
Insulin glargine
 
C267H404N72O78S6
 
118984454 
Moderate    Inter Info   
[265], [266], [267]
D0814
 
Insulin human (inhalation, rapid acting)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[265], [266], [267]
D0815
 
Insulin human (isophane)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[265], [266], [267]
D0816
 
Insulin human (regular)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[265], [266], [267]
D0817
 
Insulin human (zinc extended)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[265], [266], [267]
D0818
 
Insulin human (zinc)
 
C257H383N65O77S6
 
118984375 
Moderate    Inter Info   
[265], [266], [267]
D0819
 
Insulin lispro
 
C257H389N65O77S6
 
16132438 
Moderate    Inter Info   
[265], [266], [267]
D1015
 
Metformin
 
C4H11N5
 
4091 
Moderate    Inter Info   
[265], [266], [267]
D1064
 
Miglitol
 
C8H17NO5
 
441314 
Moderate    Inter Info   
[265], [266], [267]
D1112
 
Nateglinide
 
C19H27NO3
 
5311309 
Moderate    Inter Info   
[265], [266], [267]
D1294
 
Pioglitazone
 
C19H20N2O3S
 
4829 
Moderate    Inter Info   
[265], [266], [267]
D1392
 
Repaglinide
 
C27H36N2O4
 
65981 
Moderate    Inter Info   
[265], [266], [267]
D1429
 
Rosiglitazone
 
C18H19N3O3S
 
77999 
Moderate    Inter Info   
[265], [266], [267]
D1601
 
Tolazamide
 
C14H21N3O3S
 
5503 
Moderate    Inter Info   
[265], [266], [267]
D1603
 
Tolbutamide
 
C12H18N2O3S
 
5505 
Moderate    Inter Info   
[265], [266], [267]
   Increased risk of lowers seizure threshold Drug Num:  9
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0833
 
Iohexol
 
C19H26I3N3O9
 
3730 
Major    Inter Info   
[125], [126], [127], [128], [129]
D0834
 
Iopamidol
 
C17H22I3N3O8
 
65492 
Major    Inter Info   
[125], [126], [127], [128], [129]
D1616
 
Tramadol
 
C16H25NO2
 
33741 
Major    Inter Info   
[8], [9], [15], [16], [252], [253], [254], [255], [256], [257], [258], [259], [45], [46], [50], [260], [62], [64], [65], [72], [75], [77], [261], [78], [262], [91], [263], [264]
D0722
 
Ginkgo biloba
 
NA
 
NA
Moderate    Inter Info   
[311], [312], [49], [313], [314], [315], [316], [317]
D1287
 
Picosulfuric acid
 
C18H15NO8S2
 
5243 
Moderate    Inter Info   
[326], [327], [171]
D1308
 
Polyethylene glycol (3350 with electrolytes)
 
C2H6O2
 
174 
Moderate    Inter Info   
[326], [327], [171]
D1488
 
Sodium sulfate
 
Na2O4S
 
24436 
Moderate    Inter Info   
[326], [327], [171]
D0678
 
Fluphenazine
 
C22H26F3N3OS
 
3372 
Moderate    Inter Info   
[180], [171]
D0932
 
Lindane
 
C6H6Cl6
 
727 
Moderate    Inter Info   
[332], [333], [334]
   Increased risk of other adverse reactions (Unspecific) Drug Num:  8
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0165
 
Benzphetamine
 
C17H21N
 
5311017 
Major    Inter Info   
[71], [103], [104]
D0952
 
Lorcaserin
 
C11H14ClN
 
11658860 
Major    Inter Info   
[71], [103], [104]
D1012
 
Metamfetamine
 
C10H15N
 
10836 
Major    Inter Info   
[71], [103], [104]
D1262
 
Phendimetrazine
 
C12H17NO
 
30487 
Major    Inter Info   
[71], [103], [104]
D0486
 
Diethylpropion
 
C13H19NO
 
7029 
Major    Inter Info   
[71], [103], [104]
D0641
 
Fenfluramine
 
C12H16F3N
 
3337 
Major    Inter Info   
[71], [103], [104]
D1270
 
Phentermine
 
C10H15N
 
4771 
Major    Inter Info   
[71], [103], [104]
D1281
 
Phenylpropanolamine
 
C9H13NO
 
26934 
Major    Inter Info   
[71], [103], [104]
      Pharmacodynamic antagonistic effects
   Antagonize the effect of serotonergic agents Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0403
 
Cyproheptadine
 
C21H21N
 
2913 
Moderate    Inter Info   
[38], [91], [301]
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304 Product Information. Abilify (aripiprazole). Bristol-Myers Squibb, Princeton, NJ.
305 Product Information. Stribild (cobicistat/elvitegravir/emtricitabine/tenofov). Gilead Sciences, Foster City, CA.
306 Product Information. Vizimpro (dacomitinib). Pfizer U.S. Pharmaceuticals Group, New York, NY.
307 Product Information. Multaq (dronedarone). sanofi-aventis , Bridgewater, NJ.
308 Product Information. Cerdelga (eliglustat). Genzyme Corporation, Cambridge, MA.
309 Product Information. Inrebic (fedratinib). Celgene Corporation, Summit, NJ.
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329 Product Information. Zelboraf (vemurafenib). Genentech, South San Francisco, CA.
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334 Product Information. Kwell (lindane). Reed and Carnrick, Jersey City, NJ.
335 Product Information. Ranexa (ranolazine). Calmoseptine Inc, Huntington Beach, CA.
336 Product Information. Norvir (ritonavir). Abbott Pharmaceutical, Abbott Park, IL.
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351 Product Information. Detrol (tolterodine). Pharmacia and Upjohn, Kalamazoo, MI.