Details of Drug

Details of Drug

 Drug General Information (ID: D0334)
  Drug Name
Ciclesonide (nasal)
  Drug Type Small molecule
  Drug Synonymous
Alvesco; Omnair; Omnaris; Osonase; Osonide; Alvesco HFA; Ciclesonide [INN]; Omnaris HFA; RPR 251526; Alvesco (TN); BTR-15; BTR-15K; BY-9010; BYK-20426; KS-1165; Omnaris (TN); Omniair (TN); TBN-15; B-9207-015; Ciclesonide (JAN/USAN/INN); (R)-11beta,16alpha,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclohexanecarboxaldehyde, 21-isobutyrate
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  Disease Class CB40-CB7Z: Respiratory system disease; CA23: Asthma
  Therapeutic Class Antiallergic Agents
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C32H44O7
  InChI 1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1
  InChIKey LUKZNWIVRBCLON-GXOBDPJESA-N
  Canonical SMILES CC(C)C(=O)OCC(=O)C12C(CC3C1(CC(C4C3CCC5=CC(=O)C=CC45C)O)C)OC(O2)C6CCCCC6
  External Link
Pubchem ID 6918155
CAS Number 126544-47-6
CHEBI ID 31397
TTD ID D0K7HU
INTEDE ID DR0319
VARIDT ID DR01408

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
BM017  CYP450 enzyme inhibition
  Relation Graph
 Full list of drugs interacting with Ciclesonide (nasal)
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  27
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0080
 
Amprenavir
 
C25H35N3O6S
 
65016 
Moderate    Inter Info   
[1], [2], [3]
D0116
 
Atazanavir
 
C38H52N6O7
 
148192 
Moderate    Inter Info   
[1], [2], [3]
D0192
 
Boceprevir
 
C27H45N5O5
 
10324367 
Moderate    Inter Info   
[1], [2], [3]
D0302
 
Ceritinib
 
C28H36ClN5O3S
 
57379345 
Moderate    Inter Info   
[1], [2], [3]
D0375
 
Cobicistat
 
C40H53N7O5S2
 
25151504 
Moderate    Inter Info   
[1], [2], [3]
D0789
 
Idelalisib
 
C22H18FN7O
 
11625818 
Moderate    Inter Info   
[1], [2], [3]
D0946
 
Lonafarnib
 
C27H31Br2ClN4O2
 
148195 
Moderate    Inter Info   
[1], [2], [3]
D1505
 
Stiripentol
 
C14H18O3
 
5311454 
Moderate    Inter Info   
[1], [2], [3]
D1541
 
Telaprevir
 
C36H53N7O6
 
3010818 
Moderate    Inter Info   
[1], [2], [3]
D1653
 
Troleandomycin
 
C41H67NO15
 
202225 
Moderate    Inter Info   
[1], [2], [3]
D1660
 
Tucatinib
 
C26H24N8O2
 
51039094 
Moderate    Inter Info   
[1], [2], [3]
D0349
 
Clarithromycin
 
C38H69NO13
 
84029 
Moderate    Inter Info   
[1], [2], [3]
D0386
 
Conivaptan
 
C32H26N4O2
 
151171 
Moderate    Inter Info   
[1], [2], [3]
D0426
 
Darunavir
 
C27H37N3O7S
 
213039 
Moderate    Inter Info   
[1], [2], [3]
D0439
 
Delavirdine
 
C22H28N6O3S
 
5625 
Moderate    Inter Info   
[1], [2], [3]
D0692
 
Fosamprenavir
 
C25H36N3O9PS
 
131536 
Moderate    Inter Info   
[1], [2], [3]
D0799
 
Indinavir
 
C36H47N5O4
 
5362440 
Moderate    Inter Info   
[1], [2], [3]
D0867
 
Itraconazole
 
C35H38Cl2N8O4
 
55283 
Moderate    Inter Info   
[1], [2], [3]
D0880
 
Ketoconazole
 
C26H28Cl2N4O4
 
456201 
Moderate    Inter Info   
[1], [2], [3]
D1057
 
Miconazole
 
C18H14Cl4N2O
 
4189 
Moderate    Inter Info   
[1], [2], [3]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Moderate    Inter Info   
[1], [2], [3]
D1119
 
Nelfinavir
 
C32H45N3O4S
 
64143 
Moderate    Inter Info   
[1], [2], [3]
D1315
 
Posaconazole
 
C37H42F2N8O4
 
468595 
Moderate    Inter Info   
[1], [2], [3]
D1415
 
Ritonavir
 
C37H48N6O5S2
 
392622 
Moderate    Inter Info   
[1], [2], [3]
D1444
 
Saquinavir
 
C38H50N6O5
 
441243 
Moderate    Inter Info   
[1], [2], [3]
D1544
 
Telithromycin
 
C43H65N5O10
 
3002190 
Moderate    Inter Info   
[1], [2], [3]
D1706
 
Voriconazole
 
C16H14F3N5O
 
71616 
Moderate    Inter Info   
[1], [2], [3]
References
1 Agencia Espaola de Medicamentos y Productos Sanitarios Healthcare "Centro de informacion online de medicamentos de la AEMPS - CIMA.".
2 EMEA. European Medicines Agency "EPARs. European Union Public Assessment Reports.".
3 Product Information. Alvesco (ciclesonide). Nycomed USA, Florham Park, NJ.