Details of Drug

Details of Drug

 Drug General Information (ID: D0309)
  Drug Name
Chamomile
  Drug Type Small molecule
  Drug Synonymous
apigenin; 520-36-5; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; Chamomile; Versulin; Spigenin; Apigenol; 4',5,7-Trihydroxyflavone; Apigenine; C.I. Natural Yellow 1; 5,7,4'-Trihydroxyflavone; Pelargidenon 1449; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone; 2-(p-Hydroxyphenyl)-5,7-dihydroxychromone; UCCF 031; NSC 83244; UNII-7V515PI7F6; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; 5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one; CCRIS 3789; CHEBI:18388; CHEMBL28; EINECS 208-292-3; 4H-1-Benzopyran-4-one, 5,7-di
    Click to Show/Hide
  Therapeutic Class Herbal Products
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C15H10O5
  InChI 1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
  InChIKey KZNIFHPLKGYRTM-UHFFFAOYSA-N
  Canonical SMILES C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O
  External Link
Pubchem ID 5280443
CAS Number 520-36-5
CHEBI ID 18388
TTD ID D00RIX
VARIDT ID DR00822

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM050  Increased risk of bleeding
BM107  Attenuated pharmacological effects (Unspecific)
  Relation Graph
 Full list of drugs interacting with Chamomile
      Pharmacodynamic additive effects
   Increased risk of bleeding Drug Num:  51
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0005
 
Abciximab
 
NA
 
NA
Minor    Inter Info   
[3], [4], [5]
D0017
 
Acetylsalicylic acid
 
C9H8O4
 
2244 
Minor    Inter Info   
[6], [4], [5]
D0047
 
Alteplase
 
NA
 
NA
Minor    Inter Info   
[3], [4], [5]
D0084
 
Anagrelide
 
C10H7Cl2N3O
 
135409400 
Minor    Inter Info   
[3], [4], [5]
D0087
 
Anisindione
 
C16H12O3
 
2197 
Minor    Inter Info   
[6], [4], [5]
D0088
 
Anistreplase
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D0092
 
Antithrombin Alfa
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D0093
 
Antithrombin III human
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D0096
 
Apixaban
 
C25H25N5O4
 
10182969 
Minor    Inter Info   
[3], [4], [5]
D0102
 
Ardeparin
 
C26H42N2O37S5
 
772 
Minor    Inter Info   
[6], [4], [5]
D0104
 
Argatroban
 
C23H36N6O5S
 
92722 
Minor    Inter Info   
[3], [4], [5]
D0176
 
Betrixaban
 
C23H22ClN5O3
 
10275777 
Minor    Inter Info   
[6], [4], [5]
D0189
 
Bivalirudin
 
C98H138N24O33
 
16129704 
Minor    Inter Info   
[3], [4], [5]
D0247
 
Cangrelor
 
C17H25Cl2F3N5O12P3S2
 
9854012 
Minor    Inter Info   
[6], [4], [5]
D0250
 
Caplacizumab
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D0336
 
Cilostazol
 
C20H27N5O2
 
2754 
Minor    Inter Info   
[3], [4], [5]
D0364
 
Clopidogrel
 
C16H16ClNO2S
 
60606 
Minor    Inter Info   
[3], [4], [5]
D0414
 
Dalteparin
 
C26H42N2O37S5
 
772 
Minor    Inter Info   
[3], [4], [5]
D0415
 
Danaparoid
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Minor    Inter Info   
[3], [4], [5]
D0435
 
Defibrotide
 
C20H21N4O6P
 
135565962 
Minor    Inter Info   
[3], [4], [5]
D0481
 
Dicoumarol
 
C19H12O6
 
54676038 
Minor    Inter Info   
[6], [4], [5]
D0506
 
Dipyridamole
 
C24H40N8O4
 
3108 
Minor    Inter Info   
[3], [4], [5]
D0537
 
Drotrecogin alfa
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D0551
 
Edoxaban
 
C24H30ClN7O4S
 
10280735 
Minor    Inter Info   
[3], [4], [5]
D0574
 
Enoxaparin
 
C26H42N2O37S5
 
772 
Minor    Inter Info   
[3], [4], [5]
D0586
 
Epoprostenol
 
C20H32O5
 
5282411 
Minor    Inter Info   
[3], [4], [5]
D0588
 
Eptifibatide
 
C35H49N11O9S2
 
448812 
Minor    Inter Info   
[3], [4], [5]
D0690
 
Fondaparinux
 
C31H53N3O49S8
 
5282448 
Minor    Inter Info   
[3], [4], [5]
D0753
 
Heparin
 
C26H42N2O37S5
 
772 
Minor    Inter Info   
[3], [4], [5]
D0784
 
Ibritumomab tiuxetan
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D0792
 
Iloprost
 
C22H32O4
 
5311181 
Minor    Inter Info   
[3], [4], [5]
D0904
 
Lepirudin
 
C287H440N80O111S6
 
118856773 
Minor    Inter Info   
[6], [4], [5]
D1305
 
Plicamycin
 
C52H76O24
 
163659 
Minor    Inter Info   
[6], [4], [5]
D1328
 
Prasugrel
 
C20H20FNO3S
 
6918456 
Minor    Inter Info   
[3], [4], [5]
D1395
 
Reteplase
 
NA
 
NA
Minor    Inter Info   
[3], [4], [5]
D1417
 
Rivaroxaban
 
C19H18ClN3O5S
 
9875401 
Minor    Inter Info   
[3], [4], [5]
D1434
 
Ruxolitinib
 
C17H18N6
 
25126798 
Minor    Inter Info   
[3], [4], [5]
D1506
 
Streptokinase
 
C11H19NO2
 
9815560 
Minor    Inter Info   
[6], [4], [5]
D1518
 
Sulfinpyrazone
 
C23H20N2O3S
 
5342 
Minor    Inter Info   
[6], [4], [5]
D1550
 
Tenecteplase
 
NA
 
NA
Minor    Inter Info   
[3], [4], [5]
D1579
 
Ticagrelor
 
C23H28F2N6O4S
 
9871419 
Minor    Inter Info   
[3], [4], [5]
D1581
 
Ticlopidine
 
C14H14ClNS
 
5472 
Minor    Inter Info   
[6], [4], [5]
D1588
 
Tinzaparin
 
C26H42N2O37S5
 
772 
Minor    Inter Info   
[6], [4], [5]
D1593
 
Tirofiban
 
C22H36N2O5S
 
60947 
Minor    Inter Info   
[3], [4], [5]
D1613
 
Tositumomab
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D1614
 
Tositumomab (I-131)
 
NA
 
NA
Minor    Inter Info   
[6], [4], [5]
D1625
 
Treprostinil
 
C23H34O5
 
6918140 
Minor    Inter Info   
[3], [4], [5]
D1669
 
Urokinase
 
NA
 
NA
Minor    Inter Info   
[3], [4], [5]
D1705
 
Vorapaxar
 
C29H33FN2O4
 
10077130 
Minor    Inter Info   
[3], [4], [5]
D1711
 
Warfarin
 
C19H16O4
 
54678486 
Minor    Inter Info   
[3], [4], [5]
      Pharmacodynamic antagonistic effects
   Attenuated pharmacological effects (Unspecific) Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1691
 
Verteporfin
 
C82H84N8O16
 
11980904 
Moderate    Inter Info   
[1], [2]
References
1 Product Information. Visudyne (verteporfin) Valeant Pharmaceuticals, Costa Mesa, CA.
2 Product Information. Xatral (alfuzosin). Sanofi-Synthelabo Canada Inc, Markham, ON.
3 Heck AM, DeWitt BA, Lukes AL "Potential interactions between alternative therapies and warfarin." Am J Health Syst Pharm 57 (2000): 1221-7 quiz 1228-30. [PMID: 10902065]
4 Lambert JP, Cormier J "Potential interaction between warfarin and boldo-fenugreek." Pharmacotherapy 21 (2001): 509-12. [PMID: 11310527]
5 Miller LG "Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions." Arch Intern Med 158 (1998): 2200-11. [PMID: 9818800]
6 Heck AM, DeWitt BA, Lukes AL "Potential interactions between alternative therapies and warfarin." Am J Health Syst Pharm 57 (2000): 1221-7 quiz 1228-30. [PMID: 10902065]