Drug General Information (ID: D0308)
  Drug Name
Cevimeline
  Drug Type Small molecule
  Drug Synonymous
Evoxac; Saligren; Cevimeline [INN]; Cevimeline hydrochloride; Cevimeline hydrochloride [USAN]; Cevimeline hydrochloride hemihydrate; Cevimeline hydrochloride hydrate; AF 102B; AF102B; Fks 508; AF-102B; Cevimeline (INN); Cevimeline HCl 1/2H2O; Cevimeline hydrochloride (USAN); Cevimeline hydrochloride hydrate (JAN); Cevimeline.HCl; Evoxac (TN); FKS-508; SND-5008; SNI-2011; SNK-508; Saligren (TN); SND 5008, AF-102B, FKS-508; Cis-2-Methylspiro(1,3-oxathiolane-5,3')quinuclidine hydrochloride hydrate (2:2:1); (+-)-cis-2-Methylspiro(1,3-oxathiolane-5,3'-quinuclidine) hydrochloride, hemihydrate; (+/-)-cis-2-methylspiro(1-azabicyclo[2.2.2]octance-3,5'-(1,3)oxathiolane) hydrochloride hemihydrate; (2R,2'R)-2'-methylspiro[4-azabicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] dihydrochloride hydrate; (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane]; (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] dihydrate hydrochloride; (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] hydrate dihydrochloride; (2R,5R)-2-methylspiro[1,3-oxathiolane-5,3'-1-azabicyclo[2.2.2]octane] hydrate hydrochloride; 2-Methyspiro(1,3-oxathiolane-5,3)quinuclidine
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  Disease Class 4A43: Sjogren syndrome
  Therapeutic Class Parasympathomimetics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C10H17NOS
  InChI 1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3/t8-,10-/m1/s1
  InChIKey WUTYZMFRCNBCHQ-PSASIEDQSA-N
  Canonical SMILES CC1OC2(CN3CCC2CC3)CS1
  External Link
Pubchem ID 83898
CAS Number 107233-08-9
TTD ID D0Q4CS

Drug-Drug Interaction Network
  Sunburst Graph
AM004  Affected intra/extra-hepatic metabolism
AM006  Pharmacodynamic additive effects
AM007  Pharmacodynamic antagonistic effects
BM017  CYP450 enzyme inhibition
BM022  CYP450 enzyme induction
BM024  Competitive inhibition of metabolic enzyme
BM037  Additive cholinergic effects
BM049  Increased risk of atrioventricular block
BM051  Increased risk of bradycardia
BM091  Antagonize the effect of cholinergic agents
  Relation Graph
 Full list of drugs interacting with Cevimeline
      Affected intra/extra-hepatic metabolism
   CYP450 enzyme inhibition Drug Num:  108
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0002
 
Abametapir (topical)
 
C12H12N2
 
15664 
Moderate    Inter Info   
[3]
D0007
 
Abiraterone
 
C24H31NO
 
132971 
Moderate    Inter Info   
[4]
D0066
 
Amiodarone
 
C25H29I2NO3
 
2157 
Moderate    Inter Info   
[4]
D0069
 
Amlodipine
 
C20H25ClN2O5
 
2162 
Moderate    Inter Info   
[4]
D0080
 
Amprenavir
 
C25H35N3O6S
 
65016 
Moderate    Inter Info   
[4]
D0100
 
Aprepitant
 
C23H21F7N4O3
 
135413536 
Moderate    Inter Info   
[11], [12]
D0116
 
Atazanavir
 
C38H52N6O7
 
148192 
Moderate    Inter Info   
[4]
D0171
 
Berotralstat
 
C30H26F4N6O
 
137528262 
Moderate    Inter Info   
[13]
D0180
 
Bicalutamide
 
C18H14F4N2O4S
 
2375 
Moderate    Inter Info   
[4]
D0192
 
Boceprevir
 
C27H45N5O5
 
10324367 
Moderate    Inter Info   
[4]
D0220
 
Bupropion
 
C13H18ClNO
 
444 
Moderate    Inter Info   
[4]
D0298
 
Celecoxib
 
C17H14F3N3O2S
 
2662 
Moderate    Inter Info   
[4]
D0313
 
Chloramphenicol
 
C11H12Cl2N2O5
 
5959 
Moderate    Inter Info   
[4]
D0320
 
Chloroquine
 
C18H26ClN3
 
2719 
Moderate    Inter Info   
[4]
D0324
 
Chlorpromazine
 
C17H19ClN2S
 
2726 
Moderate    Inter Info   
[4]
D0337
 
Cimetidine
 
C10H16N6S
 
2756 
Moderate    Inter Info   
[4]
D0338
 
Cinacalcet
 
C22H22F3N
 
156419 
Moderate    Inter Info   
[4]
D0341
 
Ciprofloxacin
 
C17H18FN3O3
 
2764 
Moderate    Inter Info   
[4]
D0345
 
Citalopram
 
C20H21FN2O
 
2771 
Moderate    Inter Info   
[4]
D0349
 
Clarithromycin
 
C38H69NO13
 
84029 
Moderate    Inter Info   
[4]
D0356
 
Clobazam
 
C16H13ClN2O2
 
2789 
Moderate    Inter Info   
[4]
D0367
 
Clotrimazole
 
C22H17ClN2
 
2812 
Moderate    Inter Info   
[4]
D0375
 
Cobicistat
 
C40H53N7O5S2
 
25151504 
Moderate    Inter Info   
[4]
D0386
 
Conivaptan
 
C32H26N4O2
 
151171 
Moderate    Inter Info   
[15]
D0393
 
Crizotinib
 
C21H22Cl2FN5O
 
11626560 
Moderate    Inter Info   
[4]
D0409
 
Dacomitinib
 
C24H25ClFN5O2
 
11511120 
Moderate    Inter Info   
[4]
D0413
 
Dalfopristin
 
C34H50N4O9S
 
6323289 
Moderate    Inter Info   
[4]
D0416
 
Danazol
 
C22H27NO2
 
28417 
Moderate    Inter Info   
[4]
D0426
 
Darunavir
 
C27H37N3O7S
 
213039 
Moderate    Inter Info   
[4]
D0428
 
Dasatinib
 
C22H26ClN7O2S
 
3062316 
Moderate    Inter Info   
[16]
D0439
 
Delavirdine
 
C22H28N6O3S
 
5625 
Moderate    Inter Info   
[4]
D0457
 
Dexfenfluramine
 
C12H16F3N
 
66265 
Moderate    Inter Info   
[4]
D0467
 
Dextropropoxyphene
 
C22H29NO2
 
10100 
Moderate    Inter Info   
[4]
D0497
 
Diltiazem
 
C22H26N2O4S
 
39186 
Moderate    Inter Info   
[4]
D0502
 
Diphenhydramine
 
C17H21NO
 
3100 
Moderate    Inter Info   
[4]
D0525
 
Doxepin
 
C19H21NO
 
667477 
Moderate    Inter Info   
[4]
D0543
 
Duvelisib
 
C22H17ClN6O
 
50905713 
Moderate    Inter Info   
[4]
D0559
 
Eliglustat
 
C23H36N2O4
 
23652731 
Moderate    Inter Info   
[4]
D0577
 
Entrectinib
 
C31H34F2N6O2
 
25141092 
Moderate    Inter Info   
[4]
D0597
 
Erythromycin
 
C37H67NO13
 
12560 
Moderate    Inter Info   
[4]
D0599
 
Escitalopram
 
C20H21FN2O
 
146570 
Moderate    Inter Info   
[4]
D0638
 
Fedratinib
 
C27H36N6O3S
 
16722836 
Moderate    Inter Info   
[4]
D0641
 
Fenfluramine
 
C12H16F3N
 
3337 
Moderate    Inter Info   
[4]
D0667
 
Fluconazole
 
C13H12F2N6O
 
3365 
Moderate    Inter Info   
[4]
D0676
 
Fluoxetine
 
C17H18F3NO
 
3386 
Moderate    Inter Info   
[4]
D0678
 
Fluphenazine
 
C22H26F3N3OS
 
3372 
Moderate    Inter Info   
[4]
D0692
 
Fosamprenavir
 
C25H36N3O9PS
 
131536 
Moderate    Inter Info   
[4]
D0693
 
Fosaprepitant
 
C23H22F7N4O6P
 
135413538 
Moderate    Inter Info   
[11], [12]
D0696
 
Fosnetupitant
 
C31H35F6N4O5P
 
71544786 
Moderate    Inter Info   
[4]
D0713
 
Gefitinib
 
C22H24ClFN4O3
 
123631 
Moderate    Inter Info   
[4]
D0724
 
Givosiran
 
C78H139N11O30
 
119058042 
Moderate    Inter Info   
[4]
D0735
 
Goldenseal
 
NA
 
NA
Moderate    Inter Info   
[4]
D0749
 
Halofantrine
 
C26H30Cl2F3NO
 
37393 
Moderate    Inter Info   
[4]
D0750
 
Haloperidol
 
C21H23ClFNO2
 
3559 
Moderate    Inter Info   
[4]
D0779
 
Hydroxychloroquine
 
C18H26ClN3O
 
3652 
Moderate    Inter Info   
[4]
D0789
 
Idelalisib
 
C22H18FN7O
 
11625818 
Moderate    Inter Info   
[4]
D0793
 
Imatinib
 
C29H31N7O
 
5291 
Moderate    Inter Info   
[4]
D0799
 
Indinavir
 
C36H47N5O4
 
5362440 
Moderate    Inter Info   
[4]
D0852
 
Isavuconazonium
 
C35H35F2N8O5S+
 
6918606 
Moderate    Inter Info   
[4]
D0858
 
Isoniazid
 
C6H7N3O
 
3767 
Moderate    Inter Info   
[4]
D0867
 
Itraconazole
 
C35H38Cl2N8O4
 
55283 
Moderate    Inter Info   
[4]
D0869
 
Ivacaftor
 
C24H28N2O3
 
16220172 
Moderate    Inter Info   
[20]
D0880
 
Ketoconazole
 
C26H28Cl2N4O4
 
456201 
Moderate    Inter Info   
[4]
D0894
 
Lapatinib
 
C29H26ClFN4O4S
 
208908 
Moderate    Inter Info   
[21]
D0899
 
Lefamulin
 
C28H45NO5S
 
25185057 
Moderate    Inter Info   
[23]
D0906
 
Letermovir
 
C29H28F4N4O4
 
45138674 
Moderate    Inter Info   
[4]
D0911
 
Levamlodipine
 
C20H25ClN2O5
 
9822750 
Moderate    Inter Info   
[4]
D0946
 
Lonafarnib
 
C27H31Br2ClN4O2
 
148195 
Moderate    Inter Info   
[4]
D0952
 
Lorcaserin
 
C11H14ClN
 
11658860 
Moderate    Inter Info   
[4]
D0960
 
Lumefantrine
 
C30H32Cl3NO
 
6437380 
Moderate    Inter Info   
[4]
D1017
 
Methadone
 
C21H27NO
 
4095 
Moderate    Inter Info   
[4]
D1026
 
Methotrimeprazine
 
C19H24N2OS
 
72287 
Moderate    Inter Info   
[4]
D1074
 
Mirabegron
 
C21H24N4O2S
 
9865528 
Moderate    Inter Info   
[4]
D1117
 
Nefazodone
 
C25H32ClN5O2
 
4449 
Moderate    Inter Info   
[4]
D1119
 
Nelfinavir
 
C32H45N3O4S
 
64143 
Moderate    Inter Info   
[4]
D1127
 
Netupitant
 
C30H32F6N4O
 
6451149 
Moderate    Inter Info   
[4]
D1136
 
Nilotinib
 
C28H22F3N7O
 
644241 
Moderate    Inter Info   
[4]
D1189
 
Osilodrostat
 
C13H10FN3
 
44139752 
Moderate    Inter Info   
[4]
D1194
 
Oxamniquine
 
C14H21N3O3
 
4612 
Moderate    Inter Info   
[4]
D1221
 
Panobinostat
 
C21H23N3O2
 
6918837 
Moderate    Inter Info   
[4]
D1229
 
Paroxetine
 
C19H20FNO3
 
43815 
Moderate    Inter Info   
[4]
D1232
 
Pazopanib
 
C21H23N7O2S
 
10113978 
Moderate    Inter Info   
[4]
D1257
 
Perphenazine
 
C21H26ClN3OS
 
4748 
Moderate    Inter Info   
[4]
D1315
 
Posaconazole
 
C37H42F2N8O4
 
468595 
Moderate    Inter Info   
[4]
D1339
 
Primaquine
 
C15H21N3O
 
4908 
Moderate    Inter Info   
[4]
D1352
 
Promethazine
 
C17H20N2S
 
4927 
Moderate    Inter Info   
[4]
D1353
 
Propafenone
 
C21H27NO3
 
4932 
Moderate    Inter Info   
[4]
D1372
 
Quinine
 
C20H24N2O2
 
3034034 
Moderate    Inter Info   
[4]
D1383
 
Ranolazine
 
C24H33N3O4
 
56959 
Moderate    Inter Info   
[4]
D1398
 
Ribociclib
 
C23H30N8O
 
44631912 
Moderate    Inter Info   
[4]
D1415
 
Ritonavir
 
C37H48N6O5S2
 
392622 
Moderate    Inter Info   
[4]
D1432
 
Rucaparib
 
C19H18FN3O
 
9931954 
Moderate    Inter Info   
[4]
D1444
 
Saquinavir
 
C38H50N6O5
 
441243 
Moderate    Inter Info   
[4]
D1459
 
Selpercatinib
 
C29H31N7O3
 
134436906 
Moderate    Inter Info   
[4]
D1461
 
Sertraline
 
C17H17Cl2N
 
68617 
Moderate    Inter Info   
[4]
D1505
 
Stiripentol
 
C14H18O3
 
5311454 
Moderate    Inter Info   
[4]
D1541
 
Telaprevir
 
C36H53N7O6
 
3010818 
Moderate    Inter Info   
[4]
D1544
 
Telithromycin
 
C43H65N5O10
 
3002190 
Moderate    Inter Info   
[27], [28]
D1553
 
Terbinafine
 
C21H25N
 
1549008 
Moderate    Inter Info   
[4]
D1574
 
Thioridazine
 
C21H26N2S2
 
5452 
Moderate    Inter Info   
[4]
D1581
 
Ticlopidine
 
C14H14ClNS
 
5472 
Moderate    Inter Info   
[4]
D1653
 
Troleandomycin
 
C41H67NO15
 
202225 
Moderate    Inter Info   
[4]
D1690
 
Verapamil
 
C27H38N2O4
 
2520 
Moderate    Inter Info   
[4]
D1706
 
Voriconazole
 
C16H14F3N5O
 
71616 
Moderate    Inter Info   
[1], [29], [31]
D1709
 
Voxelotor
 
C19H19N3O3
 
71602803 
Moderate    Inter Info   
[4]
D1714
 
Zafirlukast
 
C31H33N3O6S
 
5717 
Moderate    Inter Info   
[4]
D0402
 
Cyclosporine
 
C62H111N11O12
 
5284373 
Moderate    Inter Info   
[4]
D0687
 
Fluvoxamine
 
C15H21F3N2O2
 
5324346 
Moderate    Inter Info   
[4]
   CYP450 enzyme induction Drug Num:  49
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0545
 
Echinacea
 
NA
 
NA
Moderate    Inter Info   
[1], [17]
D1546
 
Telotristat ethyl
 
C27H26ClF3N6O3
 
25181577 
Moderate    Inter Info   
[29], [30]
D0061
 
Aminoglutethimide
 
C13H16N2O2
 
2145 
Minor    Inter Info   
[4]
D0071
 
Amobarbital
 
C11H18N2O3
 
2164 
Minor    Inter Info   
[4]
D0095
 
Apalutamide
 
C21H15F4N5O2S
 
24872560 
Minor    Inter Info   
[4]
D0106
 
Armodafinil
 
C15H15NO2S
 
9690109 
Minor    Inter Info   
[32], [33], [34], [35], [36]
D0178
 
Bexarotene
 
C24H28O2
 
82146 
Minor    Inter Info   
[4]
D0194
 
Bosentan
 
C27H29N5O6S
 
104865 
Minor    Inter Info   
[4]
D0224
 
Butabarbital
 
C10H16N2O3
 
2479 
Minor    Inter Info   
[4]
D0225
 
Butalbital
 
C11H16N2O3
 
2481 
Minor    Inter Info   
[4]
D0255
 
Carbamazepine
 
C15H12N2O
 
2554 
Minor    Inter Info   
[4]
D0300
 
Cenobamate
 
C10H10ClN5O2
 
11962412 
Minor    Inter Info   
[4]
D0406
 
Dabrafenib
 
C23H20F3N5O2S2
 
44462760 
Minor    Inter Info   
[4]
D0432
 
Deferasirox
 
C21H15N3O4
 
214348 
Minor    Inter Info   
[4]
D0453
 
Dexamethasone
 
C22H29FO5
 
5743 
Minor    Inter Info   
[4]
D0554
 
Efavirenz
 
C14H9ClF3NO2
 
64139 
Minor    Inter Info   
[4]
D0555
 
Elagolix
 
C32H30F5N3O5
 
11250647 
Minor    Inter Info   
[4]
D0578
 
Enzalutamide
 
C21H16F4N4O2S
 
15951529 
Minor    Inter Info   
[4]
D0601
 
Eslicarbazepine
 
C15H14N2O2
 
9881504 
Minor    Inter Info   
[4]
D0628
 
Etravirine
 
C20H15BrN6O
 
193962 
Minor    Inter Info   
[4]
D0639
 
Felbamate
 
C11H14N2O4
 
3331 
Minor    Inter Info   
[4]
D0697
 
Fosphenytoin
 
C16H15N2O6P
 
56339 
Minor    Inter Info   
[4]
D0741
 
Griseofulvin
 
C17H17ClO6
 
441140 
Minor    Inter Info   
[4]
D0872
 
Ivosidenib
 
C28H22ClF3N6O3
 
71657455 
Minor    Inter Info   
[4]
D0901
 
Lemborexant
 
C22H20F2N4O2
 
56944144 
Minor    Inter Info   
[4]
D0953
 
Lorlatinib
 
C21H19FN6O2
 
71731823 
Minor    Inter Info   
[4]
D1040
 
Methylphenobarbital
 
C13H14N2O3
 
8271 
Minor    Inter Info   
[4]
D1078
 
Mitotane
 
C14H10Cl4
 
4211 
Minor    Inter Info   
[4]
D1081
 
Modafinil
 
C15H15NO2S
 
4236 
Minor    Inter Info   
[32], [33], [34], [35], [36]
D1099
 
Nafcillin
 
C21H22N2O5S
 
8982 
Minor    Inter Info   
[4]
D1128
 
Nevirapine
 
C15H14N4O
 
4463 
Minor    Inter Info   
[4]
D1198
 
Oxcarbazepine
 
C15H12N2O2
 
34312 
Minor    Inter Info   
[4]
D1248
 
Pentobarbital
 
C11H18N2O3
 
4737 
Minor    Inter Info   
[4]
D1258
 
Pexidartinib
 
C20H15ClF3N5
 
25151352 
Minor    Inter Info   
[4]
D1265
 
Phenobarbital
 
C12H12N2O3
 
4763 
Minor    Inter Info   
[4]
D1274
 
Phenylbutazone
 
C19H20N2O2
 
4781 
Minor    Inter Info   
[4]
D1283
 
Phenytoin
 
C15H12N2O2
 
1775 
Minor    Inter Info   
[4]
D1340
 
Primidone
 
C12H14N2O2
 
4909 
Minor    Inter Info   
[4]
D1399
 
Rifabutin
 
C46H62N4O11
 
135398743 
Minor    Inter Info   
[4]
D1400
 
Rifampicin
 
C43H58N4O12
 
135398735 
Minor    Inter Info   
[4]
D1401
 
Rifapentine
 
C47H64N4O12
 
135403821 
Minor    Inter Info   
[4]
D1453
 
Secobarbital
 
C12H18N2O3
 
5193 
Minor    Inter Info   
[4]
D1493
 
Somapacitan
 
C54H95N13O20S2
 
129894493 
Minor    Inter Info   
[4]
D1495
 
Somatrem
 
C43H72N14O14
 
5487805 
Minor    Inter Info   
[4]
D1518
 
Sulfinpyrazone
 
C23H20N2O3S
 
5342 
Minor    Inter Info   
[4]
D1538
 
Tazemetostat
 
C34H44N4O4
 
66558664 
Minor    Inter Info   
[4]
D1652
 
Troglitazone
 
C24H27NO5S
 
5591 
Minor    Inter Info   
[4]
D1687
 
Vemurafenib
 
C23H18ClF2N3O3S
 
42611257 
Minor    Inter Info   
[4]
D1494
 
Somatotropin
 
NA
 
NA
Minor    Inter Info   
[4]
   Competitive inhibition of metabolic enzyme Drug Num:  2
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1526
 
Tacrolimus
 
C44H69NO12
 
445643 
Moderate    Inter Info   
[25], [26]
D1549
 
Temsirolimus
 
C56H87NO16
 
6918289 
Moderate    Inter Info   
[25], [26]
      Pharmacodynamic additive effects
   Additive cholinergic effects Drug Num:  1
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0054
 
Amifampridine
 
C5H7N3
 
5918 
Moderate    Inter Info   
[9], [10]
   Increased risk of atrioventricular block Drug Num:  14
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0010
 
Acebutolol
 
C18H28N2O4
 
1978 
Moderate    Inter Info   
[4]
D0117
 
Atenolol
 
C14H22N2O3
 
2249 
Moderate    Inter Info   
[4]
D0173
 
Betaxolol
 
C18H29NO3
 
2369 
Moderate    Inter Info   
[4]
D0188
 
Bisoprolol
 
C18H31NO4
 
2405 
Moderate    Inter Info   
[4]
D0265
 
Carteolol
 
C16H24N2O3
 
2583 
Moderate    Inter Info   
[4]
D0267
 
Carvedilol
 
C24H26N2O4
 
2585 
Moderate    Inter Info   
[4]
D0602
 
Esmolol
 
C16H25NO4
 
59768 
Moderate    Inter Info   
[4]
D1049
 
Metoprolol
 
C15H25NO3
 
4171 
Moderate    Inter Info   
[4]
D1098
 
Nadolol
 
C17H27NO4
 
39147 
Moderate    Inter Info   
[4]
D1244
 
Penbutolol
 
C18H29NO2
 
37464 
Moderate    Inter Info   
[4]
D1293
 
Pindolol
 
C14H20N2O2
 
4828 
Moderate    Inter Info   
[4]
D1357
 
Propranolol
 
C16H21NO2
 
4946 
Moderate    Inter Info   
[4]
D1498
 
Sotalol
 
C12H20N2O3S
 
5253 
Moderate    Inter Info   
[4]
D1585
 
Timolol
 
C13H24N4O3S
 
33624 
Moderate    Inter Info   
[4]
   Increased risk of bradycardia Drug Num:  6
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D1474
 
Siponimod
 
C29H35F3N2O3
 
44599207 
Major    Inter Info   
[1], [2]
D0031
 
Alectinib
 
C30H34N4O2
 
49806720 
Moderate    Inter Info   
[7], [8]
D0204
 
Brigatinib
 
C29H39ClN7O2P
 
68165256 
Moderate    Inter Info   
[14]
D0661
 
Fingolimod
 
C19H33NO2
 
107970 
Moderate    Inter Info   
[18], [19]
D0897
 
Lasmiditan
 
C19H18F3N3O2
 
11610526 
Moderate    Inter Info   
[22]
D1211
 
Ozanimod
 
C23H24N4O3
 
52938427 
Moderate    Inter Info   
[24]
      Pharmacodynamic antagonistic effects
   Antagonize the effect of cholinergic agents Drug Num:  37
Drug ID
 
Drug Name
Formula Pubchem ID Severity Level Interaction Detail REF
D0019
 
Aclidinium
 
C26H30NO4S2+
 
11434515 
Moderate    Inter Info   
[5], [6]
D0123
 
Atropine
 
C17H23NO3
 
174174 
Moderate    Inter Info   
[5], [6]
D0124
 
Atropine (ophthalmic)
 
C17H23NO3
 
174174 
Moderate    Inter Info   
[5], [6]
D0154
 
Belladonna
 
C34H42N2O4
 
265028 
Moderate    Inter Info   
[5], [6]
D0160
 
Benzatropine
 
C21H25NO
 
1201549 
Moderate    Inter Info   
[5], [6]
D0183
 
Biperiden
 
C21H29NO
 
2381 
Moderate    Inter Info   
[5], [6]
D0353
 
Clidinium
 
C22H26NO3+
 
2784 
Moderate    Inter Info   
[5], [6]
D0370
 
Clozapine
 
C18H19ClN4
 
135398737 
Moderate    Inter Info   
[5], [6]
D0397
 
Cyclizine
 
C18H22N2
 
6726 
Moderate    Inter Info   
[5], [6]
D0399
 
Cyclopentolate (ophthalmic)
 
C17H25NO3
 
2905 
Moderate    Inter Info   
[5], [6]
D0424
 
Darifenacin
 
C28H30N2O2
 
444031 
Moderate    Inter Info   
[5], [6]
D0482
 
Dicyclomine
 
C19H35NO2
 
3042 
Moderate    Inter Info   
[5], [6]
D0498
 
Dimenhydrinate
 
C24H28ClN5O3
 
10660 
Moderate    Inter Info   
[5], [6]
D0508
 
Disopyramide
 
C21H29N3O
 
3114 
Moderate    Inter Info   
[5], [6]
D0662
 
Flavoxate
 
C24H25NO4
 
3354 
Moderate    Inter Info   
[5], [6]
D0733
 
Glycopyrronium
 
C19H28NO3+
 
3494 
Moderate    Inter Info   
[5], [6]
D0734
 
Glycopyrronium (topical)
 
C19H28NO3+
 
3494 
Moderate    Inter Info   
[5], [6]
D0760
 
Homatropine (ophthalmic)
 
C16H21NO3
 
5282593 
Moderate    Inter Info   
[5], [6]
D0782
 
Hyoscyamine
 
C17H23NO3
 
154417 
Moderate    Inter Info   
[5], [6]
D0842
 
Ipratropium
 
C20H30NO3+
 
657309 
Moderate    Inter Info   
[5], [6]
D0987
 
Meclizine
 
C25H27ClN2
 
4034 
Moderate    Inter Info   
[5], [6]
D1000
 
Mepenzolate
 
C21H26NO3+
 
4057 
Moderate    Inter Info   
[5], [6]
D1031
 
Methscopolamine
 
C18H24NO4+
 
71183 
Moderate    Inter Info   
[5], [6]
D1202
 
Oxybutynin
 
C22H31NO3
 
4634 
Moderate    Inter Info   
[5], [6]
D1343
 
Procainamide
 
C13H21N3O
 
4913 
Moderate    Inter Info   
[5], [6]
D1347
 
Procyclidine
 
C19H29NO
 
4919 
Moderate    Inter Info   
[5], [6]
D1354
 
Propantheline
 
C23H30NO3+
 
4934 
Moderate    Inter Info   
[5], [6]
D1371
 
Quinidine
 
C20H24N2O2
 
441074 
Moderate    Inter Info   
[5], [6]
D1396
 
Revefenacin
 
C35H43N5O4
 
11753673 
Moderate    Inter Info   
[5], [6]
D1450
 
Scopolamine
 
C17H21NO4
 
3000322 
Moderate    Inter Info   
[5], [6]
D1451
 
Scopolamine (ophthalmic)
 
C17H21NO4
 
3000322 
Moderate    Inter Info   
[5], [6]
D1491
 
Solifenacin
 
C23H26N2O2
 
154059 
Moderate    Inter Info   
[5], [6]
D1590
 
Tiotropium
 
C19H22NO4S2+
 
5487427 
Moderate    Inter Info   
[5], [6]
D1607
 
Tolterodine
 
C22H31NO
 
443879 
Moderate    Inter Info   
[5], [6]
D1641
 
Trihexyphenidyl
 
C20H31NO
 
5572 
Moderate    Inter Info   
[5], [6]
D1655
 
Tropicamide (ophthalmic)
 
C17H20N2O2
 
5593 
Moderate    Inter Info   
[5], [6]
D1656
 
Trospium
 
C25H30NO3+
 
5284632 
Moderate    Inter Info   
[5], [6]
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