Details of Drug

Details of Drug

 Drug General Information (ID: D0213)
  Drug Name
Bromotheophylline
  Drug Type Small molecule
  Drug Synonymous
8-Bromotheophylline; 10381-75-6; Bromotheophylline; Theophylline, 8-bromo-; 8-Bromo-1,3-dimethyl-1H-purine-2,6(3H,9H)-dione; 8-bromo-1,3-dimethyl-7H-purine-2,6-dione; 1H-Purine-2,6-dione, 8-bromo-3,7-dihydro-1,3-dimethyl-; UNII-FZG87K1MQ6; 8-Bromotheophyline; 8-bromo-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 8-bromo-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione; FZG87K1MQ6; 8-bromo-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione; 8-Bromo-1,3-dimethyl-3,7-dihydro-purine-2,6-dione; CHEMBL316160; MFCD00022664; 8-bromo-1,3-dimethyl-3,7-dihydro-1H-pyrine-2,6-dione; NCGC00167564-01; 1H-Purine-2,6-dione, 8-bromo-3,9-dihydro-1,3-dimethyl-; DSSTox_CID_24768; DSSTox_RID_80459; DSSTox_GSID_44768; CAS-10381-75-6; EINECS 233-846-6; 8-bromo-theophylline; NSC 164940; Oprea1_299436; Oprea1_509676; MLS004754491; SCHEMBL237881; DTXSID7044768; AMMD00018; Tox21_112559; BBL012666; BDBM50045345; CCG-19376; MFCD01848460; NSC164940; STK803299; AKOS000274376; AKOS001283003; Tox21_112559_1; ZINC100005670; AM85456; DB14018; GS-5727; HY-W088152; MCULE-1062341165; NSC-164940; NCGC00167564-03; NCGC00167564-04; SMR002397689; SY023545; DB-040487; B3456; CS-0130336; FT-0636693; Z3068; EN300-17892; 8-bromanyl-1,3-dimethyl-7H-purine-2,6-dione; H10528; AB01300038-01; AB01300038_03; A800812; AF-399/37411012; SR-01000479300; 1H-Purine-2, 8-bromo-3,7-dihydro-1,3-dimethyl-; SR-01000479300-1; W-108837; Q27278353; Z57161790; 8-bromo-1,3-dimethyl-1H-purine-2,6(3H, 7H)-dione; F0807-0406
    Click to Show/Hide
  Therapeutic Class Diuretics
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C7H7BrN4O2
  InChI InChI=1S/C7H7BrN4O2/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h1-2H3,(H,9,10)
  InChIKey SKTFQHRVFFOHTQ-UHFFFAOYSA-N
  Canonical SMILES CN1C2=C(C(=O)N(C1=O)C)NC(=N2)Br
  External Link
Pubchem ID 11808

Drug-Drug Interaction Network
  Sunburst Graph
AM006  Pharmacodynamic additive effects
BM042  Additive hypotensive effects
  Relation Graph
 Full list of drugs interacting with Bromotheophylline
      Pharmacodynamic additive effects
   Additive hypotensive effects Drug Num:  15
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D0156
 
Benazepril
 
C24H28N2O5
 
5362124 
Moderate    Inter Info   
[1], [2], [3]
D0254
 
Captopril
 
C9H15NO3S
 
44093 
Moderate    Inter Info   
[1], [2], [3]
D0567
 
Enalapril
 
C20H28N2O5
 
5388962 
Moderate    Inter Info   
[1], [2], [3]
D0586
 
Epoprostenol
 
C20H32O5
 
5282411 
Moderate    Inter Info   
[4], [5], [6]
D0644
 
Fenoldopam
 
C16H16ClNO3
 
3341 
Moderate    Inter Info   
[7], [8]
D0695
 
Fosinopril
 
C30H46NO7P
 
55891 
Moderate    Inter Info   
[1], [2], [3]
D0792
 
Iloprost
 
C22H32O4
 
5311181 
Moderate    Inter Info   
[4], [5], [6]
D0938
 
Lisinopril
 
C21H31N3O5
 
5362119 
Moderate    Inter Info   
[1], [2], [3]
D1082
 
Moexipril
 
C27H34N2O7
 
91270 
Moderate    Inter Info   
[1], [2], [3]
D1256
 
Perindopril
 
C19H32N2O5
 
107807 
Moderate    Inter Info   
[1], [2], [3]
D1369
 
Quinapril
 
C25H30N2O5
 
54892 
Moderate    Inter Info   
[1], [2], [3]
D1379
 
Ramipril
 
C23H32N2O5
 
5362129 
Moderate    Inter Info   
[1], [2], [3]
D1457
 
Selexipag
 
C26H32N4O4S
 
9913767 
Moderate    Inter Info   
[4], [5], [6]
D1618
 
Trandolapril
 
C24H34N2O5
 
5484727 
Moderate    Inter Info   
[1], [2], [3]
D1625
 
Treprostinil
 
C23H34O5
 
6918140 
Moderate    Inter Info   
[4], [5], [6]
References
1 Murphy BF, Whitworth JA, Kincaid-Smith P "Renal insufficiency with combinations of angiotensin converting enzyme inhibitors and diuretics." Br Med J 288 (1984): 844-5. [PMID: 6322905]
2 Product Information. Lexxel (enalapril-felodipine). Astra Pharmaceuticals, Wayne, PA.
3 Sudoh T, Fujimura A, Shiga T, et al. "Influence of lisinopril on urinary electrolytes excretion after furosemide in healthy subjects." J Clin Pharmacol 33 (1993): 640-3. [PMID: 8396158]
4 Cerner Multum, Inc. "UK Summary of Product Characteristics.".
5 Product Information. Flolan (epoprostenol). Glaxo Wellcome, Research Triangle Park, NC.
6 Product Information. Remodulin (treprostinil). United Therapeutics Corp, Silver Spring, MD.
7 Product Information. Xatral (alfuzosin). Sanofi-Synthelabo Canada Inc, Markham, ON.
8 Product Information. Corlopam (fenoldopam). Neurex, Menlo Park, CA.