Details of Drug

Details of Drug

 Drug General Information (ID: D0131)
  Drug Name
Avibactam
  Drug Type Small molecule
  Drug Synonymous
Avibactam; Avibactam free acid; NXL104; AVE-1330A free acid; 1192500-31-4; Avibactam (free acid); UNII-7352665165; CHEMBL1689063; CHEBI:85984; [(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] hydrogen sulfate; 396731-14-9; (2S,5R)-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octane-2-carboxamide; (1R,2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl hydrogen sulfate; Avibactam [USAN:INN]; Nxl-104 free acid; SCHEMBL1666807; GTPL10761; AMY24028; AVI; ZINC9302239; BDBM50339145; CS-0593; DB09060; 1,6-Diazabicyclo(3.2.1)octane-2-carboxamide, 7-oxo-6-(sulfooxy)-, (1R,2S,5R)-rel-; HY-14879; E80372; Q15410251; UNII-06MFO7817I component NDCUAPJVLWFHHB-UHNVWZDZSA-N; trans-7-oxo-6-(sulfooxy)-1,6-diazabicyclo[3.2.1]octan-2-carboxamide; SULFURIC ACID, MONO[(1R,2S,5R)-2-(AMINOCARBONYL)-7-OXO-1,6-DIAZABICYCLO[3.2.1]OCT-6-YL] ESTER
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  Therapeutic Class Cephalosporins/Beta-Lactamase Inhibitors
  Structure Could Not Find 2D Structure
3D Structure 2D Structure
  Formula C7H11N3O6S
  InChI InChI=1S/C7H11N3O6S/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15/h4-5H,1-3H2,(H2,8,11)(H,13,14,15)/t4-,5+/m1/s1
  InChIKey NDCUAPJVLWFHHB-UHNVWZDZSA-N
  Canonical SMILES C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)O)C(=O)N
  External Link
Pubchem ID 9835049
INTEDE ID DR2138

Drug-Drug Interaction Network
  Sunburst Graph
AM005  Affected excretion pathways
BM028  Competitive inhibition of renal tubular secretion
  Relation Graph
 Full list of drugs interacting with Avibactam
      Affected excretion pathways
   Competitive inhibition of renal tubular secretion Drug Num:  1
Drug ID
 
Drug Name
 Formula Pubchem ID Severity Level Interaction Detail REF
D1341
 
Probenecid
 
C13H19NO4S
 
4911 
Moderate    Inter Info   
[1]
References
1 Product Information. Avycaz (avibactam-cefTAZidime). Forest Pharmaceuticals, St. Louis, MO.