Details of Drug

Drug General Information (ID: D0002)
Drug Name	Abametapir (topical)
Drug Type	Small molecule
Drug Synonymous	5,5'-Dimethyl-2,2'-bipyridine; 1762-34-1; 5,5'-Dimethyl-2,2'-dipyridyl; 5,5'-Dimethyl-2,2'-bipyridyl; 6,6'-Bi-3-picoline; 2,2'-BIPYRIDINE, 5,5'-DIMETHYL-; HA-44; 6,6'-Di-3-picolyl; 6,6'-Di-3-picoline; UNII-6UO390AMFB; 5-methyl-2-(5-methylpyridin-2-yl)pyridine; MFCD01740554; 6UO390AMFB; CHEMBL2205807; 5,5'-dimethyl-2,2'-bipyridinyl; 5,5 -Dimethyl-2,2 -bipyridine; Xeglyze; BRN 0123183; Abametapir [USAN:INN]; Xeglyze(Abametapir); Xeglyze (TN); PubChem24353; Abametapir (USAN/INN); ACMC-209eb4; SCHEMBL351152; HA44; 2,2 -Bis-(5-methylpyridyl); DTXSID00170095; ZINC403335; 9238AA; ANW-22814; BDBM50401351; LT0042; s5752; 5,5''-Dimethyl-2,2''-bipyridine; AKOS005257775; CS-W004546; DB11932; MCULE-8581798506; SB17220; 5,5 inverted exclamation marka-Dimethyl-2,2 inverted exclamation marka-dipyridyl; 5,5'-Dimethyl-2,2'-dipyridyl, 98%; AK-63331; DS-15219; SY052805; FT-0689891; D10687; W-108621; Q27265547; 5,5 inverted exclamation mark -Dimethyl-2,2 inverted exclamation mark -bipyridyl Click to Show/Hide
Disease Class	1G00: Pediculosis
Therapeutic Class	Topical Anti-Infectives
Structure
Structure	3D Structure		2D Structure
Formula	C12H12N2
InChI	1S/C12H12N2/c1-9-3-5-11(13-7-9)12-6-4-10(2)8-14-12/h3-8H,1-2H3
InChIKey	PTRATZCAGVBFIQ-UHFFFAOYSA-N
Canonical SMILES	CC1=CN=C(C=C1)C2=NC=C(C=C2)C
External Link
	Pubchem ID	15664
	CAS Number	1762-34-1
	TTD ID	D5IS6V

Drug-Drug Interaction Network
Sunburst Graph		Legend Information AM004 Affected intra/extra-hepatic metabolism BM017 CYP450 enzyme inhibition
Relation Graph

Full list of drugs interacting with Abametapir (topical)
Affected intra/extra-hepatic metabolism
	CYP450 enzyme inhibition					Drug Num: 388
Drug ID		Drug Name	Formula	Pubchem ID	Severity Level		Interaction Detail	REF
D0044		Alpelisib	C19H22F3N5O2S	56649450	Moderate		Inter Info	[1]
D0129		Avapritinib	C26H27FN10	118023034	Moderate		Inter Info	[1]
D0204		Brigatinib	C29H39ClN7O2P	68165256	Moderate		Inter Info	[1]
D0518		Doravirine	C17H11ClF3N5O3	58460047	Moderate		Inter Info	[1]
D0589		Eravacycline	C27H31FN4O8	54726192	Moderate		Inter Info	[1]
D0638		Fedratinib	C27H36N6O3S	16722836	Moderate		Inter Info	[1]
D0683		Fluticasone	C22H27F3O4S	5311101	Moderate		Inter Info	[1]
D0720		Gilteritinib	C29H44N8O3	49803313	Moderate		Inter Info	[1]
D0725		Glasdegib	C21H22N6O	25166913	Moderate		Inter Info	[1]
D0901		Lemborexant	C22H20F2N4O2	56944144	Moderate		Inter Info	[1]
D1169		Oliceridine	C22H30N2O2S	66553195	Moderate		Inter Info	[1]
D1242		Pemigatinib	C24H27F2N5O4	86705695	Moderate		Inter Info	[1]
D1258		Pexidartinib	C20H15ClF3N5	25151352	Moderate		Inter Info	[1]
D1306		Polatuzumab vedotin	NA	NA	Moderate		Inter Info	[1]
D1324		Pralsetinib	C27H32FN9O2	129073603	Moderate		Inter Info	[2]
D1407		Rimegepant	C28H28F2N6O3	51049968	Moderate		Inter Info	[1]
D1409		Ripretinib	C24H21BrFN5O2	71584930	Moderate		Inter Info	[1]
D1432		Rucaparib	C19H18FN3O	9931954	Moderate		Inter Info	[1]
D1459		Selpercatinib	C29H31N7O3	134436906	Moderate		Inter Info	[1]
D1474		Siponimod	C29H35F3N2O3	44599207	Moderate		Inter Info	[1]
D1538		Tazemetostat	C34H44N4O4	66558664	Moderate		Inter Info	[1]
D1653		Troleandomycin	C41H67NO15	202225	Moderate		Inter Info	[1]
D1663		Ubrogepant	C29H26F3N5O3	68748835	Moderate		Inter Info	[1]
D1666		Upadacitinib	C17H19F3N6O	58557659	Moderate		Inter Info	[1]
D1709		Voxelotor	C19H19N3O3	71602803	Moderate		Inter Info	[1]
D1718		Zanubrutinib	C27H29N5O3	135565884	Moderate		Inter Info	[1]
D0007		Abiraterone	C24H31NO	132971	Moderate		Inter Info	[1]
D0008		Acalabrutinib	C26H23N7O2	71226662	Moderate		Inter Info	[1]
D0028		Albendazole	C12H15N3O2S	2082	Moderate		Inter Info	[1]
D0035		Alfentanil	C21H32N6O3	51263	Moderate		Inter Info	[1]
D0036		Alfuzosin	C19H27N5O4	2092	Moderate		Inter Info	[1]
D0038		Aliskiren	C30H53N3O6	5493444	Moderate		Inter Info	[1]
D0041		Almotriptan	C17H25N3O2S	123606	Moderate		Inter Info	[1]
D0043		Alosetron	C17H18N4O	2099	Moderate		Inter Info	[1]
D0045		Alprazolam	C17H13ClN4	2118	Moderate		Inter Info	[1]
D0066		Amiodarone	C25H29I2NO3	2157	Moderate		Inter Info	[1]
D0068		Amitriptyline	C20H23N	2160	Moderate		Inter Info	[1]
D0069		Amlodipine	C20H25ClN2O5	2162	Moderate		Inter Info	[1]
D0080		Amprenavir	C25H35N3O6S	65016	Moderate		Inter Info	[1]
D0084		Anagrelide	C10H7Cl2N3O	135409400	Moderate		Inter Info	[1]
D0096		Apixaban	C25H25N5O4	10182969	Moderate		Inter Info	[1]
D0099		Apremilast	C22H24N2O7S	11561674	Moderate		Inter Info	[1]
D0100		Aprepitant	C23H21F7N4O3	135413536	Moderate		Inter Info	[1]
D0105		Aripiprazole	C23H27Cl2N3O2	60795	Moderate		Inter Info	[1]
D0106		Armodafinil	C15H15NO2S	9690109	Moderate		Inter Info	[1]
D0108		Artemether	C16H26O5	68911	Moderate		Inter Info	[1]
D0112		Asenapine	C17H16ClNO	3036780	Moderate		Inter Info	[1]
D0115		Astemizole	C28H31FN4O	2247	Moderate		Inter Info	[1]
D0116		Atazanavir	C38H52N6O7	148192	Moderate		Inter Info	[1]
D0120		Atorvastatin	C33H35FN2O5	60823	Moderate		Inter Info	[1]
D0128		Avanafil	C23H26ClN7O3	9869929	Moderate		Inter Info	[1]
D0133		Axitinib	C22H18N4OS	6450551	Moderate		Inter Info	[1]
D0149		Bedaquiline	C32H31BrN2O2	5388906	Moderate		Inter Info	[1]
D0153		Belinostat	C15H14N2O4S	6918638	Moderate		Inter Info	[1]
D0157		Bendamustine	C16H21Cl2N3O2	65628	Moderate		Inter Info	[1]
D0165		Benzphetamine	C17H21N	5311017	Moderate		Inter Info	[1]
D0172		Betamethasone	C22H29FO5	9782	Moderate		Inter Info	[1]
D0178		Bexarotene	C24H28O2	82146	Moderate		Inter Info	[1]
D0181		Bictegravir	C21H18F3N3O5	90311989	Moderate		Inter Info	[1]
D0192		Boceprevir	C27H45N5O5	10324367	Moderate		Inter Info	[1]
D0193		Bortezomib	C19H25BN4O4	387447	Moderate		Inter Info	[1]
D0194		Bosentan	C27H29N5O6S	104865	Moderate		Inter Info	[1]
D0195		Bosutinib	C26H29Cl2N5O3	5328940	Moderate		Inter Info	[1]
D0199		Brentuximab vedotin	NA	NA	Moderate		Inter Info	[1]
D0202		Brexpiprazole	C25H27N3O2S	11978813	Moderate		Inter Info	[1]
D0212		Bromocriptine	C32H40BrN5O5	31101	Moderate		Inter Info	[1]
D0215		Budesonide	C25H34O6	5281004	Moderate		Inter Info	[1]
D0218		Bupivacaine	C18H28N2O	2474	Moderate		Inter Info	[1]
D0219		Buprenorphine	C29H41NO4	644073	Moderate		Inter Info	[1]
D0220		Bupropion	C13H18ClNO	444	Moderate		Inter Info	[1]
D0222		Buspirone	C21H31N5O2	2477	Moderate		Inter Info	[1]
D0227		Cabazitaxel	C45H57NO14	9854073	Moderate		Inter Info	[1]
D0230		Cabozantinib	C28H24FN3O5	25102847	Moderate		Inter Info	[1]
D0231		Caffeine	C8H10N4O2	2519	Moderate		Inter Info	[1]
D0251		Capmatinib	C23H17FN6O	25145656	Moderate		Inter Info	[1]
D0255		Carbamazepine	C15H12N2O	2554	Moderate		Inter Info	[1]
D0262		Cariprazine	C21H32Cl2N4O	11154555	Moderate		Inter Info	[1]
D0302		Ceritinib	C28H36ClN5O3S	57379345	Moderate		Inter Info	[1]
D0303		Cerivastatin	C26H34FNO5	446156	Moderate		Inter Info	[1]
D0308		Cevimeline	C10H17NOS	83898	Moderate		Inter Info	[1]
D0317		Chlordiazepoxide	C16H14ClN3O	2712	Moderate		Inter Info	[1]
D0324		Chlorpromazine	C17H19ClN2S	2726	Moderate		Inter Info	[1]
D0333		Ciclesonide	C32H44O7	6918155	Moderate		Inter Info	[1]
D0336		Cilostazol	C20H27N5O2	2754	Moderate		Inter Info	[1]
D0338		Cinacalcet	C22H22F3N	156419	Moderate		Inter Info	[1]
D0342		Cisapride	C23H29ClFN3O4	6917698	Moderate		Inter Info	[1]
D0345		Citalopram	C20H21FN2O	2771	Moderate		Inter Info	[1]
D0349		Clarithromycin	C38H69NO13	84029	Moderate		Inter Info	[1]
D0354		Clindamycin	C18H33ClN2O5S	446598	Moderate		Inter Info	[1]
D0356		Clobazam	C16H13ClN2O2	2789	Moderate		Inter Info	[1]
D0361		Clomipramine	C19H23ClN2	2801	Moderate		Inter Info	[1]
D0362		Clonazepam	C15H10ClN3O3	2802	Moderate		Inter Info	[1]
D0365		Clorazepic acid	C16H11ClN2O3	2809	Moderate		Inter Info	[1]
D0370		Clozapine	C18H19ClN4	135398737	Moderate		Inter Info	[1]
D0375		Cobicistat	C40H53N7O5S2	25151504	Moderate		Inter Info	[1]
D0376		Cobimetinib	C21H21F3IN3O2	16222096	Moderate		Inter Info	[1]
D0378		Cocaine (topical)	C17H21NO4	446220	Moderate		Inter Info	[1]
D0379		Codeine	C18H21NO3	5284371	Moderate		Inter Info	[1]
D0380		Colchicine	C22H25NO6	6167	Moderate		Inter Info	[1]
D0386		Conivaptan	C32H26N4O2	151171	Moderate		Inter Info	[1]
D0387		Conjugated estrogens	C18H21NaO5S	45357473	Moderate		Inter Info	[1]
D0393		Crizotinib	C21H22Cl2FN5O	11626560	Moderate		Inter Info	[1]
D0398		Cyclobenzaprine	C20H21N	2895	Moderate		Inter Info	[1]
D0400		Cyclophosphamide	C7H15Cl2N2O2P	2907	Moderate		Inter Info	[1]
D0402		Cyclosporine	C62H111N11O12	5284373	Moderate		Inter Info	[1]
D0406		Dabrafenib	C23H20F3N5O2S2	44462760	Moderate		Inter Info	[1]
D0408		Daclatasvir	C40H50N8O6	25154714	Moderate		Inter Info	[1]
D0419		Dapsone	C12H12N2O2S	2955	Moderate		Inter Info	[1]
D0424		Darifenacin	C28H30N2O2	444031	Moderate		Inter Info	[1]
D0426		Darunavir	C27H37N3O7S	213039	Moderate		Inter Info	[1]
D0428		Dasatinib	C22H26ClN7O2S	3062316	Moderate		Inter Info	[1]
D0436		Deflazacort	C25H31NO6	189821	Moderate		Inter Info	[1]
D0439		Delavirdine	C22H28N6O3S	5625	Moderate		Inter Info	[1]
D0446		Desipramine	C18H22N2	2995	Moderate		Inter Info	[1]
D0453		Dexamethasone	C22H29FO5	5743	Moderate		Inter Info	[1]
D0458		Dexlansoprazole	C16H14F3N3O2S	9578005	Moderate		Inter Info	[1]
D0466		Dextromethorphan	C18H25NO	5360696	Moderate		Inter Info	[1]
D0473		Diazepam	C16H13ClN2O	3016	Moderate		Inter Info	[1]
D0476		Diclofenac	C14H11Cl2NO2	3033	Moderate		Inter Info	[1]
D0493		Dihydrocodeine	C18H23NO3	5284543	Moderate		Inter Info	[1]
D0494		Dihydroergotamine	C33H37N5O5	10531	Moderate		Inter Info	[1]
D0497		Diltiazem	C22H26N2O4S	39186	Moderate		Inter Info	[1]
D0508		Disopyramide	C21H29N3O	3114	Moderate		Inter Info	[1]
D0511		Docetaxel	C43H53NO14	148124	Moderate		Inter Info	[1]
D0513		Dofetilide	C19H27N3O5S2	71329	Moderate		Inter Info	[1]
D0514		Dolasetron	C19H20N2O3	3033818	Moderate		Inter Info	[1]
D0516		Donepezil	C24H29NO3	3152	Moderate		Inter Info	[1]
D0524		Doxazosin	C23H25N5O5	3157	Moderate		Inter Info	[1]
D0527		Doxercalciferol	C28H44O2	5281107	Moderate		Inter Info	[1]
D0528		Doxorubicin	C27H29NO11	31703	Moderate		Inter Info	[1]
D0529		Doxorubicin (liposomal)	C27H29NO11	31703	Moderate		Inter Info	[1]
D0533		Dronabinol	C21H30O2	16078	Moderate		Inter Info	[1]
D0534		Dronedarone	C31H44N2O5S	208898	Moderate		Inter Info	[1]
D0535		Droperidol	C22H22FN3O2	3168	Moderate		Inter Info	[1]
D0536		Drospirenone	C24H30O3	68873	Moderate		Inter Info	[1]
D0539		Duloxetine	C18H19NOS	60835	Moderate		Inter Info	[1]
D0542		Dutasteride	C27H30F6N2O2	6918296	Moderate		Inter Info	[1]
D0554		Efavirenz	C14H9ClF3NO2	64139	Moderate		Inter Info	[1]
D0557		Eletriptan	C22H26N2O2S	77993	Moderate		Inter Info	[1]
D0559		Eliglustat	C23H36N2O4	23652731	Moderate		Inter Info	[1]
D0578		Enzalutamide	C21H16F4N4O2S	15951529	Moderate		Inter Info	[1]
D0585		Eplerenone	C24H30O6	443872	Moderate		Inter Info	[1]
D0592		Ergometrine	C19H23N3O2	443884	Moderate		Inter Info	[1]
D0593		Ergotamine	C33H35N5O5	8223	Moderate		Inter Info	[1]
D0595		Erlotinib	C22H23N3O4	176870	Moderate		Inter Info	[1]
D0597		Erythromycin	C37H67NO13	12560	Moderate		Inter Info	[1]
D0599		Escitalopram	C20H21FN2O	146570	Moderate		Inter Info	[1]
D0603		Esomeprazole	C17H19N3O3S	9568614	Moderate		Inter Info	[1]
D0604		Estazolam	C16H11ClN4	3261	Moderate		Inter Info	[1]
D0605		Esterified estrogens	NA	NA	Moderate		Inter Info	[1]
D0606		Estradiol	C18H24O2	5757	Moderate		Inter Info	[1]
D0607		Estradiol (topical)	C18H24O2	5757	Moderate		Inter Info	[1]
D0609		Estrone	C18H22O2	5870	Moderate		Inter Info	[1]
D0610		Estrone sulfate	C18H22O5S	3001028	Moderate		Inter Info	[1]
D0611		Estrone sulfate (topical)	C18H22O5S	3001028	Moderate		Inter Info	[1]
D0612		Eszopiclone	C17H17ClN6O3	969472	Moderate		Inter Info	[1]
D0619		Ethinylestradiol	C20H24O2	5991	Moderate		Inter Info	[1]
D0620		Ethosuximide	C7H11NO2	3291	Moderate		Inter Info	[1]
D0626		Etonogestrel	C22H28O2	6917715	Moderate		Inter Info	[1]
D0627		Etoposide	C29H32O13	36462	Moderate		Inter Info	[1]
D0628		Etravirine	C20H15BrN6O	193962	Moderate		Inter Info	[1]
D0629		Everolimus	C53H83NO14	6442177	Moderate		Inter Info	[1]
D0630		Exemestane	C20H24O2	60198	Moderate		Inter Info	[1]
D0640		Felodipine	C18H19Cl2NO4	3333	Moderate		Inter Info	[1]
D0646		Fentanyl	C22H28N2O	3345	Moderate		Inter Info	[1]
D0655		Fesoterodine	C26H37NO3	6918558	Moderate		Inter Info	[1]
D0660		Finasteride	C23H36N2O2	57363	Moderate		Inter Info	[1]
D0665		Flibanserin	C20H21F3N4O	6918248	Moderate		Inter Info	[1]
D0671		Fludrocortisone	C21H29FO5	31378	Moderate		Inter Info	[1]
D0679		Flurazepam	C21H23ClFN3O	3393	Moderate		Inter Info	[1]
D0682		Flutamide	C11H11F3N2O3	3397	Moderate		Inter Info	[1]
D0686		Fluvastatin	C24H26FNO4	446155	Moderate		Inter Info	[1]
D0692		Fosamprenavir	C25H36N3O9PS	131536	Moderate		Inter Info	[1]
D0693		Fosaprepitant	C23H22F7N4O6P	135413538	Moderate		Inter Info	[1]
D0702		Frovatriptan	C14H17N3O	77992	Moderate		Inter Info	[1]
D0713		Gefitinib	C22H24ClFN4O3	123631	Moderate		Inter Info	[1]
D0730		Glyburide	C23H28ClN3O5S	3488	Moderate		Inter Info	[1]
D0738		Granisetron	C18H24N4O	5284566	Moderate		Inter Info	[1]
D0745		Guanfacine	C9H9Cl2N3O	3519	Moderate		Inter Info	[1]
D0749		Halofantrine	C26H30Cl2F3NO	37393	Moderate		Inter Info	[1]
D0750		Haloperidol	C21H23ClFNO2	3559	Moderate		Inter Info	[1]
D0772		Hydrocodone	C18H21NO3	5284569	Moderate		Inter Info	[1]
D0773		Hydrocortisone	C21H30O5	5754	Moderate		Inter Info	[1]
D0789		Idelalisib	C22H18FN7O	11625818	Moderate		Inter Info	[1]
D0790		Ifosfamide	C7H15Cl2N2O2P	3690	Moderate		Inter Info	[1]
D0791		Iloperidone	C24H27FN2O4	71360	Moderate		Inter Info	[1]
D0793		Imatinib	C29H31N7O	5291	Moderate		Inter Info	[1]
D0795		Imipramine	C19H24N2	3696	Moderate		Inter Info	[1]
D0797		Indacaterol	C24H28N2O3	6918554	Moderate		Inter Info	[1]
D0799		Indinavir	C36H47N5O4	5362440	Moderate		Inter Info	[1]
D0845		Irinotecan	C33H38N4O6	60838	Moderate		Inter Info	[1]
D0846		Irinotecan (liposomal)	C33H38N4O6	60838	Moderate		Inter Info	[1]
D0852		Isavuconazonium	C35H35F2N8O5S+	6918606	Moderate		Inter Info	[1]
D0863		Isotretinoin	C20H28O2	5282379	Moderate		Inter Info	[1]
D0865		Isradipine	C19H21N3O5	3784	Moderate		Inter Info	[1]
D0866		Istradefylline	C20H24N4O4	5311037	Moderate		Inter Info	[1]
D0867		Itraconazole	C35H38Cl2N8O4	55283	Moderate		Inter Info	[1]
D0868		Ivabradine	C27H36N2O5	132999	Moderate		Inter Info	[1]
D0869		Ivacaftor	C24H28N2O3	16220172	Moderate		Inter Info	[1]
D0870		Ivermectin	C48H74O14	6321424	Moderate		Inter Info	[1]
D0873		Ixabepilone	C27H42N2O5S	6445540	Moderate		Inter Info	[1]
D0874		Ixazomib	C14H19BCl2N2O4	25183872	Moderate		Inter Info	[1]
D0879		Ketamine	C13H16ClNO	3821	Moderate		Inter Info	[1]
D0880		Ketoconazole	C26H28Cl2N4O4	456201	Moderate		Inter Info	[1]
D0892		Lansoprazole	C16H14F3N3O2S	3883	Moderate		Inter Info	[1]
D0894		Lapatinib	C29H26ClFN4O4S	208908	Moderate		Inter Info	[1]
D0907		Letrozole	C17H11N5	3902	Moderate		Inter Info	[1]
D0909		Levacetylmethadol	C23H31NO2	15130	Moderate		Inter Info	[1]
D0916		Levobupivacaine	C18H28N2O	92253	Moderate		Inter Info	[1]
D0922		Levonorgestrel	C21H28O2	13109	Moderate		Inter Info	[1]
D0927		Lidocaine	C14H22N2O	3676	Moderate		Inter Info	[1]
D0930		Linagliptin	C25H28N8O2	10096344	Moderate		Inter Info	[1]
D0944		Lomitapide	C39H37F6N3O2	9853053	Moderate		Inter Info	[1]
D0946		Lonafarnib	C27H31Br2ClN4O2	148195	Moderate		Inter Info	[1]
D0950		Loratadine	C22H23ClN2O2	3957	Moderate		Inter Info	[1]
D0954		Losartan	C22H23ClN6O	3961	Moderate		Inter Info	[1]
D0956		Lovastatin	C24H36O5	53232	Moderate		Inter Info	[1]
D0959		Lumateperone	C24H28FN3O	21302490	Moderate		Inter Info	[1]
D0961		Lurasidone	C28H36N4O2S	213046	Moderate		Inter Info	[1]
D0966		Macitentan	C19H20Br2N6O4S	16004692	Moderate		Inter Info	[1]
D0980		Maraviroc	C29H41F2N5O	3002977	Moderate		Inter Info	[1]
D0990		Medroxyprogesterone acetate	C24H34O4	6279	Moderate		Inter Info	[1]
D0992		Mefloquine	C17H16F6N2O	4046	Moderate		Inter Info	[1]
D0993		Megestrol acetate	C24H32O4	11683	Moderate		Inter Info	[1]
D0994		Melatonin	C13H16N2O2	896	Moderate		Inter Info	[1]
D0995		Meloxicam	C14H13N3O4S2	54677470	Moderate		Inter Info	[1]
D1001		Meperidine	C15H21NO2	4058	Moderate		Inter Info	[1]
D1003		Mephenytoin	C12H14N2O2	4060	Moderate		Inter Info	[1]
D1017		Methadone	C21H27NO	4095	Moderate		Inter Info	[1]
D1037		Methylergometrine	C20H25N3O2	8226	Moderate		Inter Info	[1]
D1041		Methylprednisolone	C22H30O5	6741	Moderate		Inter Info	[1]
D1054		Mexiletine	C11H17NO	4178	Moderate		Inter Info	[1]
D1060		Midazolam	C18H13ClFN3	4192	Moderate		Inter Info	[1]
D1062		Midostaurin	C35H30N4O4	9829523	Moderate		Inter Info	[1]
D1063		Mifepristone	C29H35NO2	55245	Moderate		Inter Info	[1]
D1074		Mirabegron	C21H24N4O2S	9865528	Moderate		Inter Info	[1]
D1075		Mirtazapine	C17H19N3	4205	Moderate		Inter Info	[1]
D1081		Modafinil	C15H15NO2S	4236	Moderate		Inter Info	[1]
D1087		Montelukast	C35H36ClNO3S	5281040	Moderate		Inter Info	[1]
D1097		Nabumetone	C15H16O2	4409	Moderate		Inter Info	[1]
D1101		Naldemedine	C32H34N4O6	54732242	Moderate		Inter Info	[1]
D1104		Naloxegol	C34H53NO11	56959087	Moderate		Inter Info	[1]
D1109		Naproxen	C14H14O3	156391	Moderate		Inter Info	[1]
D1112		Nateglinide	C19H27NO3	5311309	Moderate		Inter Info	[1]
D1117		Nefazodone	C25H32ClN5O2	4449	Moderate		Inter Info	[1]
D1119		Nelfinavir	C32H45N3O4S	64143	Moderate		Inter Info	[1]
D1127		Netupitant	C30H32F6N4O	6451149	Moderate		Inter Info	[1]
D1128		Nevirapine	C15H14N4O	4463	Moderate		Inter Info	[1]
D1130		Nicardipine	C26H29N3O6	4474	Moderate		Inter Info	[1]
D1133		Nicotine	C10H14N2	89594	Moderate		Inter Info	[1]
D1134		Nifedipine	C17H18N2O6	4485	Moderate		Inter Info	[1]
D1136		Nilotinib	C28H22F3N7O	644241	Moderate		Inter Info	[1]
D1139		Nintedanib	C31H33N5O4	135423438	Moderate		Inter Info	[1]
D1141		Nisoldipine	C20H24N2O6	4499	Moderate		Inter Info	[1]
D1143		Nitisinone	C14H10F3NO5	115355	Moderate		Inter Info	[1]
D1154		Norethisterone	C20H26O2	6230	Moderate		Inter Info	[1]
D1157		Norgestrel	C21H28O2	13109	Moderate		Inter Info	[1]
D1166		Olanzapine	C17H20N4S	135398745	Moderate		Inter Info	[1]
D1167		Olaparib	C24H23FN4O3	23725625	Moderate		Inter Info	[1]
D1179		Omeprazole	C17H19N3O3S	4594	Moderate		Inter Info	[1]
D1181		Ondansetron	C18H19N3O	4595	Moderate		Inter Info	[1]
D1189		Osilodrostat	C13H10FN3	44139752	Moderate		Inter Info	[1]
D1190		Osimertinib	C28H33N7O2	71496458	Moderate		Inter Info	[1]
D1202		Oxybutynin	C22H31NO3	4634	Moderate		Inter Info	[1]
D1203		Oxycodone	C18H21NO4	5284603	Moderate		Inter Info	[1]
D1212		Paclitaxel	C47H51NO14	36314	Moderate		Inter Info	[1]
D1213		Paclitaxel (protein-bound)	C47H51NO14	36314	Moderate		Inter Info	[1]
D1214		Palbociclib	C24H29N7O2	5330286	Moderate		Inter Info	[1]
D1221		Panobinostat	C21H23N3O2	6918837	Moderate		Inter Info	[1]
D1222		Pantoprazole	C16H15F2N3O4S	4679	Moderate		Inter Info	[1]
D1226		Paricalcitol	C27H44O3	5281104	Moderate		Inter Info	[1]
D1232		Pazopanib	C21H23N7O2S	10113978	Moderate		Inter Info	[1]
D1251		Pentoxifylline	C13H18N4O3	4740	Moderate		Inter Info	[1]
D1291		Pimecrolimus (topical)	C43H68ClNO11	6509979	Moderate		Inter Info	[1]
D1292		Pimozide	C28H29F2N3O	16362	Moderate		Inter Info	[1]
D1294		Pioglitazone	C19H20N2O3S	4829	Moderate		Inter Info	[1]
D1299		Pirfenidone	C12H11NO	40632	Moderate		Inter Info	[1]
D1312		Pomalidomide	C13H11N3O4	134780	Moderate		Inter Info	[1]
D1313		Ponatinib	C29H27F3N6O	24826799	Moderate		Inter Info	[1]
D1330		Praziquantel	C19H24N2O2	4891	Moderate		Inter Info	[1]
D1332		Prednisolone	C21H28O5	5755	Moderate		Inter Info	[1]
D1334		Prednisone	C21H26O5	5865	Moderate		Inter Info	[1]
D1336		Pretomanid	C14H12F3N3O5	456199	Moderate		Inter Info	[1]
D1348		Progesterone	C21H30O2	5994	Moderate		Inter Info	[1]
D1349		Progesterone (topical)	C21H30O2	5994	Moderate		Inter Info	[1]
D1353		Propafenone	C21H27NO3	4932	Moderate		Inter Info	[1]
D1356		Propofol	C12H18O	4943	Moderate		Inter Info	[1]
D1357		Propranolol	C16H21NO2	4946	Moderate		Inter Info	[1]
D1367		Quazepam	C17H11ClF4N2S	4999	Moderate		Inter Info	[1]
D1368		Quetiapine	C21H25N3O2S	5002	Moderate		Inter Info	[1]
D1370		Quinestrol	C25H32O2	9046	Moderate		Inter Info	[1]
D1371		Quinidine	C20H24N2O2	441074	Moderate		Inter Info	[1]
D1372		Quinine	C20H24N2O2	3034034	Moderate		Inter Info	[1]
D1373		Rabeprazole	C18H21N3O3S	5029	Moderate		Inter Info	[1]
D1378		Ramelteon	C16H21NO2	208902	Moderate		Inter Info	[1]
D1385		Rasagiline	C12H13N	3052776	Moderate		Inter Info	[1]
D1387		Regorafenib	C21H15ClF4N4O3	11167602	Moderate		Inter Info	[1]
D1392		Repaglinide	C27H36N2O4	65981	Moderate		Inter Info	[1]
D1394		Retapamulin (topical)	C30H47NO4S	6918462	Moderate		Inter Info	[1]
D1398		Ribociclib	C23H30N8O	44631912	Moderate		Inter Info	[1]
D1399		Rifabutin	C46H62N4O11	135398743	Moderate		Inter Info	[1]
D1404		Rilpivirine	C22H18N6	6451164	Moderate		Inter Info	[1]
D1405		Riluzole	C8H5F3N2OS	5070	Moderate		Inter Info	[1]
D1413		Risperidone	C23H27FN4O2	5073	Moderate		Inter Info	[1]
D1415		Ritonavir	C37H48N6O5S2	392622	Moderate		Inter Info	[1]
D1417		Rivaroxaban	C19H18ClN3O5S	9875401	Moderate		Inter Info	[1]
D1422		Roflumilast	C17H14Cl2F2N2O3	449193	Moderate		Inter Info	[1]
D1423		Rolapitant	C25H26F6N2O2	10311306	Moderate		Inter Info	[1]
D1424		Romidepsin	C24H36N4O6S2	5352062	Moderate		Inter Info	[1]
D1427		Ropinirole	C16H24N2O	5095	Moderate		Inter Info	[1]
D1428		Ropivacaine	C17H26N2O	175805	Moderate		Inter Info	[1]
D1434		Ruxolitinib	C17H18N6	25126798	Moderate		Inter Info	[1]
D1440		Salmeterol	C25H37NO4	5152	Moderate		Inter Info	[1]
D1444		Saquinavir	C38H50N6O5	441243	Moderate		Inter Info	[1]
D1449		Saxagliptin	C18H25N3O2	11243969	Moderate		Inter Info	[1]
D1455		Selegiline	C13H17N	26757	Moderate		Inter Info	[1]
D1457		Selexipag	C26H32N4O4S	9913767	Moderate		Inter Info	[1]
D1461		Sertraline	C17H17Cl2N	68617	Moderate		Inter Info	[1]
D1464		Sibutramine	C17H26ClN	5210	Moderate		Inter Info	[1]
D1465		Sildenafil	C22H30N6O4S	135398744	Moderate		Inter Info	[1]
D1466		Silodosin	C25H32F3N3O4	5312125	Moderate		Inter Info	[1]
D1473		Simvastatin	C25H38O5	54454	Moderate		Inter Info	[1]
D1476		Sirolimus	C51H79NO13	5284616	Moderate		Inter Info	[1]
D1491		Solifenacin	C23H26N2O2	154059	Moderate		Inter Info	[1]
D1496		Sonidegib	C26H26F3N3O3	24775005	Moderate		Inter Info	[1]
D1512		Sufentanil	C22H30N2O2S	41693	Moderate		Inter Info	[1]
D1522		Sunitinib	C22H27FN4O2	5329102	Moderate		Inter Info	[1]
D1524		Suvorexant	C23H23ClN6O2	24965990	Moderate		Inter Info	[1]
D1525		Tacrine	C13H14N2	1935	Moderate		Inter Info	[1]
D1526		Tacrolimus	C44H69NO12	445643	Moderate		Inter Info	[1]
D1527		Tadalafil	C22H19N3O4	110635	Moderate		Inter Info	[1]
D1533		Tamoxifen	C26H29NO	2733526	Moderate		Inter Info	[1]
D1534		Tamsulosin	C20H28N2O5S	129211	Moderate		Inter Info	[1]
D1536		Tasimelteon	C15H19NO2	10220503	Moderate		Inter Info	[1]
D1541		Telaprevir	C36H53N7O6	3010818	Moderate		Inter Info	[1]
D1544		Telithromycin	C43H65N5O10	3002190	Moderate		Inter Info	[1]
D1549		Temsirolimus	C56H87NO16	6918289	Moderate		Inter Info	[1]
D1551		Teniposide	C32H32O13S	452548	Moderate		Inter Info	[1]
D1553		Terbinafine	C21H25N	1549008	Moderate		Inter Info	[1]
D1555		Terfenadine	C32H41NO2	5405	Moderate		Inter Info	[1]
D1558		Testosterone	C19H28O2	6013	Moderate		Inter Info	[1]
D1559		Testosterone (topical)	C19H28O2	6013	Moderate		Inter Info	[1]
D1570		Theophylline	C7H8N4O2	2153	Moderate		Inter Info	[1]
D1571		Thiabendazole	C10H7N3S	5430	Moderate		Inter Info	[1]
D1575		Thiotepa	C6H12N3PS	5453	Moderate		Inter Info	[1]
D1578		Tiagabine	C20H25NO2S2	60648	Moderate		Inter Info	[1]
D1579		Ticagrelor	C23H28F2N6O4S	9871419	Moderate		Inter Info	[1]
D1587		Tinidazole	C8H13N3O4S	5479	Moderate		Inter Info	[1]
D1592		Tipranavir	C31H33F3N2O5S	54682461	Moderate		Inter Info	[1]
D1596		Tizanidine	C9H8ClN5S	5487	Moderate		Inter Info	[1]
D1600		Tofacitinib	C16H20N6O	9926791	Moderate		Inter Info	[1]
D1607		Tolterodine	C22H31NO	443879	Moderate		Inter Info	[1]
D1608		Tolvaptan	C26H25ClN2O3	216237	Moderate		Inter Info	[1]
D1612		Toremifene	C26H28ClNO	3005573	Moderate		Inter Info	[1]
D1615		Trabectedin	C39H43N3O11S	108150	Moderate		Inter Info	[1]
D1616		Tramadol	C16H25NO2	33741	Moderate		Inter Info	[1]
D1623		Trastuzumab emtansine	NA	NA	Moderate		Inter Info	[1]
D1624		Trazodone	C19H22ClN5O	5533	Moderate		Inter Info	[1]
D1626		Tretinoin	C20H28O2	444795	Moderate		Inter Info	[1]
D1628		Triamcinolone	C21H27FO6	31307	Moderate		Inter Info	[1]
D1631		Triamterene	C12H11N7	5546	Moderate		Inter Info	[1]
D1632		Triazolam	C17H12Cl2N4	5556	Moderate		Inter Info	[1]
D1652		Troglitazone	C24H27NO5S	5591	Moderate		Inter Info	[1]
D1660		Tucatinib	C26H24N8O2	51039094	Moderate		Inter Info	[1]
D1664		Ulipristal	C28H35NO3	13559281	Moderate		Inter Info	[1]
D1673		Valbenazine	C24H38N2O4	24795069	Moderate		Inter Info	[1]
D1674		Valdecoxib	C16H14N2O3S	119607	Moderate		Inter Info	[1]
D1682		Vardenafil	C23H32N6O4S	135400189	Moderate		Inter Info	[1]
D1686		Velpatasvir	C49H54N8O8	67683363	Moderate		Inter Info	[1]
D1687		Vemurafenib	C23H18ClF2N3O3S	42611257	Moderate		Inter Info	[1]
D1688		Venetoclax	C45H50ClN7O7S	49846579	Moderate		Inter Info	[1]
D1689		Venlafaxine	C17H27NO2	5656	Moderate		Inter Info	[1]
D1690		Verapamil	C27H38N2O4	2520	Moderate		Inter Info	[1]
D1695		Vilanterol	C24H33Cl2NO5	10184665	Moderate		Inter Info	[1]
D1696		Vilazodone	C26H27N5O2	6918314	Moderate		Inter Info	[1]
D1697		Vinblastine	C46H58N4O9	13342	Moderate		Inter Info	[1]
D1698		Vincristine	C46H56N4O10	5978	Moderate		Inter Info	[1]
D1699		Vincristine (liposome)	C46H56N4O10	5978	Moderate		Inter Info	[1]
D1700		Vinorelbine	C45H54N4O8	5311497	Moderate		Inter Info	[1]
D1705		Vorapaxar	C29H33FN2O4	10077130	Moderate		Inter Info	[1]
D1706		Voriconazole	C16H14F3N5O	71616	Moderate		Inter Info	[1]
D1711		Warfarin	C19H16O4	54678486	Moderate		Inter Info	[1]
D1716		Zaleplon	C17H15N5O	5719	Moderate		Inter Info	[1]
D1721		Zileuton	C11H12N2O2S	60490	Moderate		Inter Info	[1]
D1726		Ziprasidone	C21H21ClN4OS	60854	Moderate		Inter Info	[1]
D1728		Zolmitriptan	C16H21N3O2	60857	Moderate		Inter Info	[1]
D1729		Zolpidem	C19H21N3O	5732	Moderate		Inter Info	[1]
D1730		Zonisamide	C8H8N2O3S	5734	Moderate		Inter Info	[1]

References
1	Product Information. Xeglyze (abametapir topical). Dr. Reddy's Laboratories Inc, Upper Saddle River, NJ.
2	Product Information. Gavreto (pralsetinib). Blueprint Medicines Corporation, Cambridge, MA.

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